Magnetic resonance imaging of sacroiliitis in early seronegative spondylarthropathy. Abnormalities correlated to clinical and laboratory findings

ABSTRACT Objective: To report on a case of malignant hyperthermia in a child after a magnetic resonance imaging of the skull was performed using sevoflurane anesthesia. Case description: A 3-year-old boy admitted to the pediatric intensive care unit after presenting clinical and laboratory findings consistent with unspecified viral meningoencephalitis. While the patient was sedated, a magnetic resonance imaging of the skul was performed using propofol followed by the administration of sevoflurane through a laryngeal mask in order to continue anesthesia. Approximately three hours after the start of the procedure, the patient presented persistent tachycardia, tachypnea, generalized muscular stiffness and hyperthermia. With a diagnostic hypothesis of malignant hyperthermia, dantrolene was then administered, which immediately induced muscle stiffness, tachycardia, tachypnea and reduced body temperature. Comments: Malignant hyperthermia is a rare pharmacogenetic syndrome characterized by a severe hypermetabolic reaction after the administration of halogenated inhalational anesthetics or depolarizing muscle relaxants such as succinylcholine, or both. Although it is a potentially fatal disease, the rapid administration of continued doses dantrolene has drastically reduced the morbidity and mortality of the disease.

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249. Evaluation of 99 Radiologically-proven Osteomyelitis Cases

Open Forum Infectious Diseases ◽

10.1093/ofid/ofab466.451 ◽

2021 ◽

Vol 8 (Supplement_1) ◽

pp. S232-S232

Author(s):

Olcay Buse Kenanoğlu ◽

Gunel Quliyeva ◽

Tansu Yamazhan ◽

Bilgin Arda ◽

Meltem Taşbakan ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Clinical Response ◽

Clinical Laboratory ◽

Clinical Signs ◽

Surgical Debridement ◽

Purulent Discharge ◽

Resonance Imaging ◽

Duration Of Treatment ◽

Laboratory Findings

Abstract Background Herein we aimed to evaluate osteomyelitis cases in our setting. Methods We evaluated the hospital records of patients with osteomyelitis between January 2013 and December 2020 retrospectively. Osteomyelitis was confirmed by direct radiography or magnetic resonance imaging or pathology. Demographic features, risk factors, clinical/laboratory findings, treatment response and mortality rates were evaluated. Clinical response was defined as (resolution of clinical signs including fever and purulent discharge and other symptoms) and/or negative culture at the end of antimicrobial therapy. Results Patients were 33 female, aged 29–85 years (mean 59±12.6). Fourty nine of the patients were diabetic foot infection, 30 were spondylodiscitis, eight were primary, seven were post-traumatic, and five were post-surgical osteomyelitis. Overall 62 patients had diabetes mellitus and 16 patients had chronic renal failure. Peripheral arterial disease, neuropathy, diabetic retinopathy and venous insufficiency rate in the DM subgroup is shown in table. Fever was present in 24.2% of the cohort. İncreasing of CRP was in 95,9%, erythrocyte sedimentation rate in 83,9%, and leukocytosis in 37.3%. The radiological findings of osteomyelitis were detected via magnetic resonance imaging in 73 patients. Etiology in biopsy cultures were elucidated in 59.5% and the most common pathogen was S. aureus (30%) Table1. The most common empirical treatment regimens were tigecycline in 27 patients, ampicillin/sulbactam in 19 patients and ceftriaxone+teicoplanin in 12 cases. Duration of treatment was 36,2±17.3 days (range 6-104 days). Overall, clinical response was obtained in 91.9%. Fifty patients were performed surgical procedure + antibacterial treatment, clinical response was 96% (p:0.091). Surgical debridement could be performed in 22 patients, clinical response was obtained in all (p:0.193). Thirteen patients developed recurrence within one year. Sixty-seven patients received oral consecutive treatment after discharge. In hospital mortality rate was 2/99 (2,02%). Conclusion Despite surgical debridement and/or developed antimicrobial treatment, approximately 1/5 of osteomyelitis cases required further treatment Further interventions seem to be needed to reach better outcomes. Disclosures All Authors: No reported disclosures

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Magnetic resonance imaging and diffusion‐weighted imaging in methylmalonic acidemia

Acta Radiologica ◽

10.1080/02841850510020888 ◽

2005 ◽

Vol 46 (1) ◽

pp. 101-103 ◽

Cited By ~ 14

Author(s):

A. Yeşildağ ◽

A. Ayata ◽

B. Baykal ◽

M. Koroglu ◽

H. Yıldız ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Diffusion Weighted Imaging ◽

Methylmalonic Acidemia ◽

Resonance Imaging ◽

Laboratory Findings ◽

Diffusion Weighted ◽

Magnetic Resonance Imaging Mri ◽

The Brain ◽

And Diffusion

Methylmalonic acidemia (MMA) is an inborn disorder of amino acid metabolism, often presenting with neurological symptoms. We present the results of magnetic resonance imaging (MRI) and diffusion‐weighted imaging (DWI) of the brain in a 16‐month‐old male patient with classic neurological and laboratory findings for MMA. MRI demonstrated the hyperintensity within globi pallidi both on T2‐weighted image and DWI during the acute episode of metabolic acidosis.

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Magnetic Resonance Imaging Evaluation of Monostotic Fibrous Dysplasia of the Tibia

Journal of the American Podiatric Medical Association ◽

10.7547/87507315-91-6-306 ◽

2001 ◽

Vol 91 (6) ◽

pp. 306-310 ◽

Cited By ~ 3

Author(s):

Jeffrey C. Karr ◽

James A. Black ◽

Joshua M. Bernard

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Fibrous Dysplasia ◽

Clinical Presentation ◽

Bone Biopsy ◽

Disease Process ◽

Resonance Imaging ◽

Imaging Studies ◽

Imaging Evaluation ◽

Laboratory Findings

The authors present a case report documenting the evaluation of monostotic fibrous dysplasia by magnetic resonance imaging. This type of evaluation demonstrates specificity for this disease process when combined with other imaging studies, laboratory findings, and clinical presentation. This technique is extremely useful in the identification of a no-touch lesion, allowing avoidance of an unnecessary bone biopsy. (J Am Podiatr Med Assoc 91(6): 306-310, 2001)

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Diffusion-weighted Magnetic Resonance Imaging in the Early Diagnosis of Neonatal Adrenoleukodystrophy

Journal of Clinical Imaging Science ◽

10.4103/2156-7514.78530 ◽

2011 ◽

Vol 1 ◽

pp. 20 ◽

Cited By ~ 2

Author(s):

R Nuri Sener ◽

Mehmet H Atalar

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Diffusion Mri ◽

Resonance Imaging ◽

Baby Girl ◽

Laboratory Findings ◽

Neonatal Adrenoleukodystrophy ◽

First Case ◽

Weighted Magnetic Resonance Imaging ◽

Magnetic Resonance Imaging Mri

A newborn baby girl developed seizures right after birth. On the fourth day, the baby was examined using diffusion sequence magnetic resonance imaging (MRI) and diagnosed to have neonatal adrenoleukodystrophy. Laboratory findings confirmed the diagnosis. This is the first case of neonatal adrenoleukodystrophy (NALD) where diffusion MRI sequence helped in the diagnosis. We find association of NALD with seizures at birth is an extremely rare occurrence, and so far, only one case has been mentioned in the literature.

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A Boy with Limping and Hip Pain

Iranian Journal of Pediatrics ◽

10.5812/ijp.117882 ◽

2021 ◽

Vol In Press (In Press) ◽

Author(s):

Kosar Asna Ashari ◽

Mohamedreza Abdosalehi ◽

Fatemeh Tahghighi

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Gluteus Maximus ◽

Hip Pain ◽

Joint Effusion ◽

Past Medical History ◽

Resonance Imaging ◽

Laboratory Findings ◽

Magnetic Resonance Imaging Mri ◽

Joint Laboratory

: We presented a 5-year-old boy with fever, limping, and hip pain for six days. There was no abnormal past medical history. He kept his left leg immobile and slightly flexed, and externally rotated in the hip joint. Laboratory findings showed leukocytosis and elevated ESR and CRP. Hip sonography was normal. Hip magnetic resonance imaging (MRI) found no joint effusion but elucidated signs of inflammation in muscles of the periarticular and proximal femoral area (iliopsoas and gluteus maximus), and no collection could be noticed. We provided a thorough discussion on differential diagnoses and approaches to the patient.

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Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids, a mimicker of malignancy: a case report and review of the literature

Journal of Medical Case Reports ◽

10.1186/s13256-021-02814-5 ◽

2021 ◽

Vol 15 (1) ◽

Author(s):

Eric Zhuang ◽

Lisa Shane ◽

Nima Ramezan ◽

Ameera F. Ismail ◽

Nilesh L. Vora

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Primary Lung Cancer ◽

High Dose ◽

Resonance Imaging ◽

Rapid Improvement ◽

Laboratory Findings ◽

Radiographic Findings ◽

Multiple Structures ◽

The Brain

Abstract Background Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids is a clinically and radiographically distinct inflammatory syndrome affecting multiple structures of the brain, including the cerebellum, brainstem, and spinal cord. The clinical presentation can be variable, including ataxia, nystagmus, dysarthria, dysphagia, and other subacute brainstem, cranial nerve, or cerebellar symptoms. These symptoms can be subacute to chronic, episodic, and progressive, making the diagnosis challenging. The hallmark radiographic magnetic resonance imaging findings are gadolinium-enhancing punctate lesions predominantly “peppering” the pons in a perivascular pattern. Case presentation Here, we describe a case and literature review of a 74-year-old Caucasian male who presented with subacute symptoms of ataxia, diplopia, and generalized fatigue. Physical examination was notable for horizontal nystagmus and wide-based gait. Magnetic resonance imaging revealed angiocentric enhancement predominantly in the brainstem and cerebellum, with involvement of the basal ganglia, thalami, and supratentorial white matter. Meanwhile, a screening computed tomography scan demonstrated a right upper lobe mass with biopsy proving primary lung cancer. Biopsy of one of the brain lesions showed perivascular infiltrate primarily composed of CD3+ T cells, scattered CD20+ B cells, and no signs of malignancy. The patient was started on high-dose glucocorticoids followed by a maintenance regimen with rapid improvement clinically and radiographically. Given extensive work-up was negative, these clinical and radiographic findings were consistent with chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids. Conclusions This case illustrates the difficulty of diagnosing chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids, given its variable presentation, lack of specific laboratory findings, and poorly understood pathogenesis. We demonstrate a case that responded well to oral corticosteroid burst followed by a taper to the lowest corticosteroid dose clinically possible. Failure to recognize this syndrome could result in permanent central nervous system morbidity. Therefore, earlier recognition is crucial for this treatable condition.

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Spinal Epidural Abscess: A Ten-Year Perspective

Neurosurgery ◽

10.1227/00006123-199008000-00001 ◽

1990 ◽

Vol 27 (2) ◽

pp. 177-184 ◽

Cited By ~ 281

Author(s):

Mary Louise Hlavin ◽

Henry J. Kaminski ◽

Jeffery S. Ross ◽

Edward Ganz

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Epidural Abscess ◽

Surgical Intervention ◽

Imaging Modality ◽

Spinal Epidural Abscess ◽

Resonance Imaging ◽

Laboratory Findings ◽

Prognostic Features ◽

Spinal Epidural

Abstract A retrospective study of spinal epidural abscess spanning 10 years and encompassing 40 patients was done. Epidemiology, clinical features, laboratory findings, radiographic imaging, therapy, and outcome were examined and compared with previous series. An increasing incidence of the disease (up to 1.96 patients per 10,000 admissions per year) and an older, more debilitated population (67% having factors predisposing them to infection) were discovered. Over half of the population was studied with magnetic resonance imaging, which was found to be equally as sensitive (91%) as myelography with computed tomography (92%). Magnetic resonance imaging offers the advantages of being noninvasive and able to delineate other entities, which makes it the imaging modality of choice. Preoperative paralysis and neurological deterioration from normal were identified as poor prognostic features. Of 7 patients with preoperative paralysis, 5 died, and the rest failed to recover neurological function. Eleven patients with initially normal neurological exams deteriorated in the hospital before surgical intervention. Eight of these patients were being treated with appropriate antibiotics; 2 became paralyzed despite more than 3 weeks of antibiotic therapy. Only 3 of these 11 patients recovered fully. Immediate surgical decompression combined with antibiotics remains the treatment of choice.

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Relationship between tuberculous otomastoiditis and tuberculous meningitis

The Journal of Laryngology & Otology ◽

10.1017/s0022215107000540 ◽

2007 ◽

Vol 122 (9) ◽

pp. 893-897 ◽

Cited By ~ 2

Author(s):

G Sonmez ◽

V Turhan ◽

M G Senol ◽

E Ozturk ◽

H O Sildiroglu ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Differential Diagnosis ◽

Magnetic Resonance ◽

Antibiotic Therapy ◽

Causal Relationship ◽

Tuberculous Meningitis ◽

Clinical Condition ◽

Resonance Imaging ◽

Laboratory Findings ◽

Meningeal Involvement

AbstractObjective:The aim of this study was to determine the correlation between tuberculous meningitis and tuberculous otomastoiditis.Materials and methods:Meningeal involvement sites were investigated by magnetic resonance imaging in 32 patients (21 males, 11 females) who had previously been diagnosed with tuberculous meningitis. Clinical and laboratory findings and responses to anti-tuberculous treatment were evaluated, and the presence of concomitant tuberculous otomastoiditis was also investigated.Results:The meningeal involvement site was unilateral (in the sylvian fissure and the perimesencephalic cistern) in 28 patients (87.5 per cent), and bilateral and widespread in four patients (12.5 per cent). Tuberculous otomastoiditis was found in 11 of the patients with tuberculous meningitis (34.3 per cent). Otomastoiditis was on the same side as the meningeal involvement in nine of these 11 patients. Bilateral otomastoiditis with meningeal involvement was observed in two patients.Conclusions:Tuberculous meningitis is frequently accompanied by otomastoiditis, although the exact causal relationship between the two conditions is unclear. Since meningitis is a serious clinical condition, concomitant otomastoiditis generally remains unrecognised. Tuberculosis should be considered in the differential diagnosis of patients with otitis or otomastoiditis who do not respond to antibiotic therapy.

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