Low-intensity pulsed ultrasound for chronic patellar tendinopathy: a randomized, double-blind, placebo-controlled trial

ABSTRACT Objectives: To evaluate the effects of low-intensity pulsed ultrasound (LIPUS) on orthodontically induced tooth root resorption caused by torque in human subjects. Materials and Methods: Ten healthy patients (12–35 years of age) who required extraction of all first premolars as a part of their routine orthodontic treatment were recruited. A 15° twist was applied in the arch wire using 0.019 × 0.025-inch TMA in a 0.022-inch bracket system (Synergy R) that produced a buccal root torque of approximately 5 N/mm at the bracket level. Using a split mouth design, randomization, and blinding, one side of the arch received LIPUS for 20 minutes per day for 4 weeks at an incident intensity of 30 mW/cm2 of the transducers’ surface area. The other side served as a self-control, which received a sham transducer. After 4 weeks, all first premolars were extracted and micro–computed tomographic analysis was performed on these extracted teeth. A linear mixed-model statistical analysis was used. Results: LIPUS-treated teeth showed significantly less total volume of resorption lacunae compared to control teeth by a mean difference of (0.54 ± 0.09 mm3) (P < .001) and percentage of root resorption by a mean difference of (0.33 ± 0.05 mm3) (P < .001). In addition, significantly fewer resorption lacunae were found on all root surfaces in the LIPUS group compared to the control except in the instance of the distal surface. Limitations: This study was performed on limited number of cases during a 4-week period. Conclusions: LIPUS minimizes root resorption when applied during torque tooth movement over a 4-week period.

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Effects of low intensity pulsed ultrasound to reduce the effusion volumes and pain with knee osteoarthritis: a randomized controlled trial

International Journal of Research in Orthopaedics ◽

10.18203/issn.2455-4510.intjresorthop20185145 ◽

2018 ◽

Vol 5 (1) ◽

pp. 77

Author(s):

P. Shanmuga Raju ◽

Chokkarapu Ramu ◽

N. S. Harshavardhan ◽

K. Rajender ◽

G. Sachin

Keyword(s):

Randomized Controlled Trial ◽

Knee Osteoarthritis ◽

Controlled Trial ◽

Control Group ◽

Ultrasound Therapy ◽

Pulsed Ultrasound ◽

Low Intensity Pulsed Ultrasound ◽

Low Intensity ◽

Randomized Controlled ◽

And Control

Background: The study aim was to determine the effect of low intensity pulsed ultrasound therapy to reduce the effusion volumes and pain in patients with Knee OA.Methods: This study design was randomized controlled trial. Total 50 patients diagnosed with Knee osteoarthritis were randomly assigned to two groups. Group I was using treatment of low intensity pulsed ultrasound therapy and group II was administered TENS with home exercise respectively. Treatments were 6 days per week and duration of 2 week. The amount of effusion volume will be measured via ultrasonograpy in knee.Results: The maximum number of cases are lying in age group >60 years which is 28% and 40% in cases and control group respectively and age distribution in both the group is statistically not significant. The mean age of patients in cases and control group is 57.08±7.40 years and 58.04±9.93 years respectively.Conclusions: Low intensity pulsed ultrasound therapy significantly reduced the effusion volumes and pain in patients with knee osteoarthritis.

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Efficacy and safety of novel low-intensity pulsed ultrasound (LIPUS) in treating mild to moderate erectile dysfunction: a multicenter, randomized, double-blind, sham-controlled clinical study

Translational Andrology and Urology ◽

10.21037/tau.2019.07.03 ◽

2019 ◽

Vol 8 (4) ◽

pp. 307-319 ◽

Cited By ~ 5

Author(s):

Wanshou Cui ◽

Huixi Li ◽

Ruili Guan ◽

Meng Li ◽

Bicheng Yang ◽

...

Keyword(s):

Erectile Dysfunction ◽

Clinical Study ◽

Efficacy And Safety ◽

Pulsed Ultrasound ◽

Double Blind ◽

Low Intensity Pulsed Ultrasound ◽

Low Intensity ◽

Controlled Clinical Study

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Effect of Low Intensity Pulsed Ultrasound (LIPUS) on Tooth Movement and Root Resorption: A Prospective Multi-Center Randomized Controlled Trial

Journal of Clinical Medicine ◽

10.3390/jcm9030804 ◽

2020 ◽

Vol 9 (3) ◽

pp. 804 ◽

Cited By ~ 4

Author(s):

Tarek El-Bialy ◽

Khaled Farouk ◽

Terry D. Carlyle ◽

William Wiltshire ◽

Robert Drummond ◽

...

Keyword(s):

Tooth Movement ◽

Root Resorption ◽

Controlled Trial ◽

Control Group ◽

Pulsed Ultrasound ◽

Low Intensity Pulsed Ultrasound ◽

Low Intensity ◽

Control Side ◽

Before And After ◽

Group 1

The aim of this study was to evaluate the possible effect of low intensity pulsed ultrasound (LIPUS) on tooth movement and root resorption in orthodontic patients. Twenty-one patients were included in a split-mouth study design (group 1). Ten additional patients were included with no LIPUS device being used and this group was used as the negative control group (group 2). Group 1 patients were given LIPUS devices that were randomly assigned to right or left side on upper or lower arches. LIPUS was applied to the assigned side that was obtained by randomization, using transducers that produce ultrasound with a pulse frequency of 1.5 MHz, a pulse repetition rate of 1 kHz, and average output intensity of 30 mW/cm2. Cone-beam computed tomography (CBCT) images were taken before and after treatment. The extraction space dimensions were measured every four weeks and root lengths of canines were measured before and after treatment. The data were analyzed using paired t-test. The study outcome showed that the mean rate of tooth movement in LIPUS side was 0.266 ± 0.092 mm/week and on the control side was 0.232 ± 0.085 mm/week and the difference was statistically significant. LIPUS increased the rate of tooth movement by an average of 29%. For orthodontic root resorption, the LIPUS side (0.0092 ± 0.022 mm/week) showed a statistically significant decrease as compared to control side (0.0223 ± 0.022 mm/week). The LIPUS application accelerated tooth movement and minimized orthodontically induced tooth root resorption at the same time.

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Effects of Low-Intensity Pulsed Ultrasound on Pain and Functional Disability in Patients With Early-Stage Lumbar Spondylolysis: A Randomized Controlled Trial

10.21203/rs.3.rs-598951/v1 ◽

2021 ◽

Author(s):

Fahad Tanveer ◽

Syed Asadullah Arslan ◽

Haider Darain ◽

Ashfaq Ahmad ◽

Syed Amir Gilani ◽

...

Keyword(s):

Functional Disability ◽

Rating Scale ◽

Early Stage ◽

Controlled Trial ◽

Pulsed Ultrasound ◽

Invasive Treatment ◽

Low Intensity Pulsed Ultrasound ◽

Low Intensity ◽

Lumbar Spondylolysis

Abstract Background: Low Intensity Pulsed Ultrasound (LIPUS) is beneficial in accelerating fracture recovery, enhancing their capacity to execute tasks of daily life and, as a result, their autonomy. Methods: Thirty-four (29 males and 5 females) pre-diagnosed patients referred by an orthopaedic surgeon exhibiting symptomatic low back pain for at least four months were recruited and randomly divided into LIPUS group and Routine Physical Therapy (RPT) group. The lottery method was used to randomly assign patients into two groups. Numeric Pain Rating Scale (NPRS) was utilized for the measurement of pain and Oswestry Disability Index (ODI) for functional disability. Patients were assessed at baseline, at the end of 12th and 20 th week. Interventions were applied by the physical therapist having more than eight years of clinical experience for 10 weeks on alternate days. Results: LIPUS group reported greater reduction in pain with mean change of 3.18 points (95% CI: 2.2, 4.2; p < 0.001) at 12 th week, 6.18 points (95% CI: 5.5, 6.8; p < 0.001) at 20th week follow-up and functional disability with mean change of 28.24 points (95% CI: 23.7, 36 32.8; p < 0.001) at 12th week and 39.47 points (95% CI: 31.8, 47.1; p < 0.001) at 20th week follow-up compared with the RPT group.Conclusion: Low-intensity pulsed ultrasound has significantly reduced pain and functional disability in patients with early-stage lumbar spondylolysis and could be preferred as a safe non-invasive treatment method for early bone healing. Trial registration: WHO-Iranian registry of clinical trials (IRCT20200206046396N1, Dated: 02/05/2020).

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