scholarly journals The effect of sleep restriction on cognitive performance in elite cognitive performers: a systematic review

SLEEP ◽  
2021 ◽  
Author(s):  
Tim D Smithies ◽  
Adam J Toth ◽  
Ian C Dunican ◽  
John A Caldwell ◽  
Magdalena Kowal ◽  
...  
Keyword(s):  
Cognitive Performance ◽  
Cognitive Outcomes ◽  
Sleep Restriction ◽  
Performance Deficits ◽  
Safety Critical ◽  
Literature Searches ◽  
Serial Reaction ◽  
Significant Performance ◽  
Psychomotor Vigilance ◽  
High Salience

Abstract Study Objectives To synthesize original articles exploring the effects of sleep restriction on cognitive performance specifically for Elite Cognitive Performers, i.e. those who engage in cognitively demanding tasks with critical or safety-critical outcomes in their occupation or area of expertise. Methods Backward snowballing techniques, gray literature searches, and traditional database searches (Embase, MEDLINE, Web of Science, Google Scholar, PSYCinfo, and SportDiscus) were used to obtain relevant articles. A quality assessment was performed, and the risk of training effects was considered. Results were narratively synthesized. Fourteen articles fit the criteria. Cognitive outcomes were divided into three categories defined by whether cognitive demands were “low-salience,” “high-salience stable,” or “high-salience flexible.” Results Low-salience tests (i.e. psychomotor vigilance tasks & serial reaction tests), mainly requiring vigilance and rudimentary attentional capacities, were sensitive to sleep restriction, however, this did not necessarily translate to significant performance deficits on low-salience occupation-specific task performance. High-salience cognitive outcomes were typically unaffected unless when cognitive flexibility was required. Conclusions Sleep restriction is of particular concern to occupations whereby individuals perform (1) simple, low-salience tasks or (2) high-salience tasks with demands on the flexible allocation of attention and working memory, with critical or safety-critical outcomes.

scholarly journals 0300 The Circadian Timing of Sleep Affects the Rate of Accumulation of Neurobehavioral Impairment Across Days of Sleep Restriction

SLEEP ◽  
2020 ◽  
Vol 43 (Supplement_1) ◽  
pp. A113-A114
Author(s):  
M E McCauley ◽  
H Van Dongen ◽  
S Banks ◽  
D F Dinges
Keyword(s):  
Young Adults ◽  
Dose Response ◽  
Sleep Restriction ◽  
Circadian Timing ◽  
Performance Deficits ◽  
Response Effect ◽  
Psychomotor Vigilance Test ◽  
Dose Response Effect ◽  
Psychomotor Vigilance ◽  
Nighttime Sleep

Abstract Introduction Chronic restriction of nighttime sleep to less than ~8h/day leads to build-up of neurobehavioral impairment across days. Although it is known that sleep loss effects depend on the circadian timing of sleep, it is not known how the timing of restricted sleep influences the accumulation of neurobehavioral impairment over days. Here we studied the accumulation of impairment across days of restricted sleep placed in the morning or afternoon. Methods N=71 healthy young adults (39% female; ages 21-45y, mean±SD: 27.9±6.6y) completed a 14-day laboratory study. After two baseline days with nighttime sleep (8h TIB: 23:30-07:30), subjects were randomized to 10 consecutive days of A) morning sleep at 4h, 6h, or 8h TIB ending at 11:30 each day (n=18, 8, 8, respectively), or B) afternoon sleep at 4h, 6h, or 8h TIB ending at 19:30 each day (n=13, 17, 7, respectively). Subjects were tested on the 10min psychomotor vigilance test (PVT) every ~2 hours during scheduled wakefulness. Daily averages for PVT lapses (RTs>500ms) observed between 2h and 14h after awakening were analyzed with non-linear mixed-effects regression to investigate differences in the neurobehavioral impairment build-up rate between sleep restriction conditions. Results Afternoon sleep conditions showed a significant sleep dose-response effect (p<0.001), with the fastest accrual of PVT performance deficits across days in the 4h condition, and slow-to-negligible accumulation (p=0.36) of PVT performance deficits in the 8h condition. However, morning sleep resulted in no significant sleep dose-response effect (p=0.96). All 3 morning sleep doses displayed negligible (p≥0.12) accumulation of impairment across days. Conclusion In this sample of young adults, sleep dosages ending in the morning (at 11:30) appear to provide considerable protection against cumulative performance deficits from sleep restricted to 4h-6h/day over 10 days, suggesting that the afternoon circadian promotion of wakefulness can sustain behavioral alertness even over multiple days of repeated sleep restriction. Support NIH grants R01-NR04281 and M01-RR00040

293 Predictive utility of a brief scale to identify U.S. Army Soldiers who are genetically vulnerable and resilient to sleep loss

SLEEP ◽  
2021 ◽  
Vol 44 (Supplement_2) ◽  
pp. A117-A117
Author(s):  
Janna Mantua ◽  
Carolyn Mickelson ◽  
Jacob Naylor ◽  
Bradley Ritland ◽  
Alexxa Bessey ◽  
...  
Keyword(s):  
Decision Making ◽  
Reaction Time ◽  
Sleep Deprivation ◽  
Cognitive Performance ◽  
Response Inhibition ◽  
Sleep Loss ◽  
Cutoff Score ◽  
Cognitive Subscale ◽  
Army Soldiers ◽  
Psychomotor Vigilance

Abstract Introduction Sleep loss that is inherent to military operations can lead to cognitive errors and potential mission failure. Single Nucleotide Polymorphisms (SNPs) allele variations of several genes (COMT, ADORA2A, TNFa, CLOCK, DAT1) have been linked with inter-individual cognitive resilience to sleep loss through various mechanisms. U.S. Army Soldiers with resilience-related alleles may be better-suited to perform cognitively-arduous duties under conditions of sleep loss than those without these alleles. However, military-wide genetic screening is costly, arduous, and infeasible. This study tested whether a brief survey of subjective resilience to sleep loss (1) can demarcate soldiers with and without resilience-related alleles, and, if so, (2) can predict cognitive performance under conditions of sleep loss. Methods Six SNPs from the aforementioned genes were sequenced from 75 male U.S. Army special operations Soldiers (age 25.7±4.1). Psychomotor vigilance, response inhibition, and decision-making were tested after a night of mission-driven total sleep deprivation. The Iowa Resilience to Sleeplessness Test (iREST) Cognitive Subscale, which measures subjective cognitive resilience to sleep loss, was administered after a week of recovery sleep. A receiver operating characteristic (ROC) curve was used to determine whether the iREST Cognitive Subscale can discriminate between gene carriers, and a cutoff score was determined. Cognitive performance after sleep deprivation was compared between those below/above the cutoff score using t-tests or Mann-Whitney U tests. Results The iREST discriminated between allele variations for COMT (ROC=.65,SE=.07,p=.03), with an optimal cutoff score of 3.03 out of 5, with 90% sensitivity and 51.4% specificity. Soldiers below the cutoff score had significantly poorer for psychomotor vigilance reaction time (t=-2.39,p=.02), response inhibition errors of commission (U=155.00,W=246.00,p=.04), and decision-making reaction time (t=2.13,p=.04) than Soldiers above the cutoff score. Conclusion The iREST Cognitive Subscale can discriminate between those with and without specific vulnerability/resilience-related genotypes. If these findings are replicated, the iREST Cognitive Subscale could be used to help military leaders make decisions about proper personnel placement when sleep loss is unavoidable. This would likely result in increased safety and improved performance during military missions. Support (if any) Support for this study came from the Military Operational Medicine Research Program of the United States Army Medical Research and Development Command.

scholarly journals 0260 IMPACT OF SLEEP RESTRICTION AND RECOVERY ON MOTIVATION DURING REPEATED COGNITIVE PERFORMANCE TESTING

SLEEP ◽  
2017 ◽  
Vol 40 (suppl_1) ◽  
pp. A95-A96
Author(s):  
D Lange ◽  
E Hennecke ◽  
J Fronczek ◽  
A Bauer ◽  
D Aeschbach ◽  
...  
Keyword(s):  
Cognitive Performance ◽  
Performance Testing ◽  
Sleep Restriction

scholarly journals Mediterranean Lifestyle in Relation to Cognitive Health: Results from the HELIAD Study

Nutrients ◽  
2018 ◽  
Vol 10 (10) ◽  
pp. 1557 ◽  
Author(s):  
Costas Anastasiou ◽  
Mary Yannakoulia ◽  
Meropi Kontogianni ◽  
Mary Kosmidis ◽  
Eirini Mamalaki ◽  
...  
Keyword(s):  
Cognitive Performance ◽  
Population Based ◽  
Lifestyle Factors ◽  
Cognitive Outcomes ◽  
Lifestyle Factor ◽  
Population Based Study ◽  
Cognitive Domains ◽  
Domain Specific ◽  
Z Scores ◽  
Lifestyle Pattern

Many lifestyle factors have been linked to cognitive function but little is known about their combined effect. An overall lifestyle pattern for people living in the Mediterranean basin has been proposed, including diet, but also physical activity, sleep and daily living activities with social/intellectual aspects. We aimed to examine the associations between a combination of these lifestyle factors and detailed cognitive performance. A total of 1716 participants from the Hellenic Longitudinal Investigation of Ageing and Diet (HELIAD), a population-based study of participants ≥65 years, were included in this analysis. Lifestyle factors were evaluated using standard, validated questionnaires and a Total Lifestyle Index (TLI) was constructed. Cognitive outcomes included mild cognitive impairment (MCI) diagnosis, a composite z-score (either continuous or with a threshold at the 25th percentile) and z-scores for five cognitive domains. A higher TLI was associated with 65% reduced odds for MCI in the non-demented individuals and 43% reduced odds for low global cognition when MCI participants were excluded, a risk reduction equivalent to 9 and 2.7 fewer years of ageing, respectively. Each lifestyle factor was differentially associated with domain-specific cognitive performance. Our results suggest that a TLI, more so than single lifestyle parameters, may be related to cognitive performance.

Research … How Fun Is That? Interesting Questions Relative to the Effects of Exercise on Cognitive Performance

2014 ◽  
Vol 3 (3) ◽  
pp. 151-160 ◽  
Author(s):  
Jennifer L. Etnier
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
Cognitive Functioning ◽  
Cognitive Performance ◽  
Cognitive Outcomes ◽  
Future Research ◽  
North American Society ◽  
National Meeting ◽  
The North ◽  
American Society

In developing a senior lecture for the 2014 national meeting of the North American Society for the Psychology of Sport and Physical Activity, I had the opportunity to reflect upon a career of research and to focus on three interesting questions that my colleagues and I have attempted to address. These questions have led to several studies that all revolve around identifying ways to increase the effects of exercise on cognitive performance. In particular, the questions examine the possibility of increasing effects by focusing on particular populations (e.g., older adults, children) and by increasing our understanding of dose-response relationships between exercise parameters (e.g., intensity, duration) and cognitive outcomes. I present empirical evidence relative to each of these questions and provide directions for future research on physical activity and cognitive functioning.

scholarly journals Effect of revascularization on cognitive outcomes in intracranial steno-occlusive disease: a systematic review

2019 ◽  
Vol 46 (2) ◽  
pp. E14 ◽  
Author(s):  
Bradley Kolb ◽  
Hassan Fadel ◽  
Gary Rajah ◽  
Hamidreza Saber ◽  
Ali Luqman ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cognitive Decline ◽  
Cognitive Performance ◽  
Observational Studies ◽  
English Language ◽  
Randomized Trials ◽  
Occlusive Disease ◽  
Cognitive Outcomes ◽  
Thomson Reuters ◽  
Before And After

OBJECTIVESteno-occlusive diseases of the cerebral vasculature have been associated with cognitive decline. The authors performed a systematic review of the existing literature on intracranial steno-occlusive disease, including intracranial atherosclerosis and moyamoya disease (MMD), to determine the extent and quality of evidence for the effect of revascularization on cognitive performance.METHODSA systematic search of PubMed/MEDLINE, the Thomson Reuters Web of Science Core Collection, and the KCI Korean Journal Database was performed to identify randomized controlled trials (RCTs) in the English-language literature and observational studies that compared cognitive outcomes before and after revascularization in patients with steno-occlusive disease of the intracranial vasculature, from which data were extracted and analyzed.RESULTSNine papers were included, consisting of 2 RCTs and 7 observational cohort studies. Results from 2 randomized trials including 142 patients with symptomatic intracranial atherosclerotic steno-occlusion found no additional benefit to revascularization when added to maximal medical therapy. The certainty in the results of these trials was limited by concerns for bias and indirectness. Results from 7 observational trials including 282 patients found some cognitive benefit for revascularization for symptomatic atherosclerotic steno-occlusion and for steno-occlusion related to MMD in children. The certainty of these conclusions was low to very low, due to both inherent limitations in observational studies for inferring causality and concerns for added risk of bias and indirectness in some studies.CONCLUSIONSThe effects of revascularization on cognitive performance in intracranial steno-occlusive disease remain uncertain due to limitations in existing studies. More well-designed randomized trials and observational studies are needed to determine if revascularization can arrest or reverse cognitive decline in these patients.

Higher probability of prodromal Parkinson disease is related to lower cognitive performance

Neurology ◽  
2019 ◽  
Vol 92 (19) ◽  
pp. e2261-e2272 ◽  
Author(s):  
Anastasia Bougea ◽  
Maria I. Maraki ◽  
Mary Yannakoulia ◽  
Maria Stamelou ◽  
Georgia Xiromerisiou ◽  
...  
Keyword(s):  
Parkinson Disease ◽  
Cognitive Performance ◽  
Neuropsychological Testing ◽  
Population Based ◽  
Cognitive Outcomes ◽  
Limited Information ◽  
Neuropsychological Battery ◽  
Cognitive Domains ◽  
Clinical Onset ◽  
Z Scores

ObjectiveGiven the limited information on cognitive function before Parkinson disease (PD) clinical onset in the general population, we sought to assess prodromal PD (pPD) probability and relate it to detailed cognitive performance in a community cohort.MethodsIn a population-based cohort of 1,629 dementia-free and PD-free participants ≥65 years of age in Greece, we assessed probability of pPD according to the International Parkinson and Movement Disorder Society's criteria. Clinical cognitive diagnoses (cognitively unimpaired, mild cognitive impairment [MCI], dementia) considering neuropsychological testing and functional status were assigned in consensus conferences. Cognitive performance in 5 cognitive domains was assessed by a detailed neuropsychological battery and summarized in the form of z scores. We investigated associations between pPD probability (and its individual constituents) and cognitive outcomes.ResultsThe median probability of pPD was 1.81% (0.2%–96.7%). Participants with MCI had higher probability of pPD compared to those with normal cognition (p < 0.001). Higher probability of pPD was related to lower performance in all cognitive domains (memory, language, executive, attention, and visuospatial function) (p < 0.001). Lower cognitive performance was further associated with certain nonmotor markers of pPD, such as daytime somnolence, depression, urinary dysfunction, constipation, and subthreshold parkinsonism (p < 0.001).ConclusionsHigher probability of pPD was associated with lower cognitive performance in all domains and higher probability of MCI. This may reflect a widespread pathologic process although future studies are warranted to infer causality. These results suggest to clinicians that they should assess cognition early, and to researchers that they should further look into the possible mechanisms that may underlie this observation.

scholarly journals The Relation Between Cognitive Performance and Symptom Factors Following Concussion

2019 ◽  
Vol 34 (5) ◽  
pp. 764-764
Author(s):  
E Whitley ◽  
R Gerkin ◽  
A Kontos ◽  
C Quintana ◽  
B Nalepa ◽  
...  
Keyword(s):  
Cognitive Performance ◽  
Verbal Memory ◽  
Visual Memory ◽  
Injury Severity ◽  
Clinical Importance ◽  
Retrospective Chart Review ◽  
Symptom Assessment ◽  
Cognitive Outcomes ◽  
Motor Speed ◽  
And Gender

Abstract Purpose The purpose of this study was to explore if symptom factors are related to cognitive outcomes. Prior studies have examined the relationship of individual symptoms to cognition. However, the relation between empirically-derived symptom factors and cognitive outcomes has yet to be explored. Methods Data were extracted via retrospective chart review of 691 patients (aged 10–24, mean: 14.99±2.63). Participants completed ImPACT and the PCSS within 14 days of injury (mean: 9.27±3.37). Predictors were PCSS factor scores of Cognitive-Fatigue-Migraine (CFM), Affective (AFF), Somatic (SOM), and Sleep (SLP) (Kontos et al., 2012). Outcomes examined were ImPACT composite scores. Univariate analyses were performed and values with p < 0.10 were entered into stepwise linear regression (LR) models. Retained predictors in each LR model had p values <.05. Results Verbal memory was predicted by CFM, SOM, age, and gender. Visual memory was predicted by CFM and SOM. Visual motor speed was predicted by age, gender, CFM, SOM, and AFF. Reaction time was best predicted by SOM, CFM, and age. The variance explained was fairly small (0.08 to 0.21). SLP was not a significant predictor in any LR. Conclusion CFM and SOM factors were most predictive of lower cognitive performance, similar to prior studies linking dizziness to longer recovery and post-traumatic migraine to worse cognitive performance. These findings underscore the clinical importance of diverse symptom assessment and injury education. Higher CFM and SOM scores may also serve as proxy for injury severity, which we would expect to be associated with worse cognitive performance.

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