Epidemiology and Outcomes of Early Morning Neuroparalytic Syndrome Following Snake Bite—A Retrospective Study

2020 ◽  
Vol 66 (4) ◽  
pp. 435-440
Author(s):  
Madhusudan Samprathi ◽  
Vipul Gupta ◽  
Muralidharan Jayashree ◽  
Arun Bansal ◽  
Arun Baranwal ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Intensive Care ◽  
Retrospective Study ◽  
Rural Areas ◽  
Tertiary Care ◽  
Early Morning ◽  
North India ◽  
Care Hospital ◽  
Snake Envenomation ◽  
Younger Age

Abstract Objective Snake envenomation has been poorly studied in developing countries. ‘Early morning neuroparalytic syndrome’ (EMNS), the classical clinical constellation caused by krait bites, refers to nighttime, indoor bites where nonspecific symptoms progress to neuroparalysis. Literature regarding EMNS in children is scarce. This study was planned to describe the clinical profile, intensive care needs and predictors of outcome in children with EMNS. Methods It is a retrospective study of children below 12 years admitted with a clinical diagnosis of snake envenomation to the pediatric intensive care unit (PICU) of a tertiary care hospital in North India. Patient records were reviewed from the electronic patient database manager. Comparison was made between the EMNS group and the non-EMNS group and between survivors and nonsurvivors within the EMNS group. Results Of the 111 children with snake envenomation, 76 had neuroparalysis (68%) and 51 had EMNS. In the EMNS cohort, 37 (72.5%) belonged to rural areas, 46 (90.2%) had indoor bites and 39 (76.5%) were witnessed. Patients with EMNS were more likely to have absent fang marks, hypoxemia at admission, bulbar palsy and need for PICU admission. Mortality rate was 13.7% in EMNS; predictors included younger age, presence of ptosis, cardiac arrest at admission and nonavailability of PICU bed (univariable analysis) but none of them independently predicted mortality. Conclusion Younger age, presence of ptosis, cardiac arrest at admission and nonavailability of intensive care beds increase the risk of mortality in children with EMNS. Timely recognition and respiratory support may reduce mortality in these children.

scholarly journals Study of Profile, Pattern and Outcome of Oral Poisoning Cases admitted in Emergency Department of a Tertiary Care Teaching Hospital in North India.

JMS SKIMS ◽  
2018 ◽  
Vol 21 (1) ◽  
pp. 24-30
Author(s):  
Susan Jalali ◽  
Shahnawaz Hamid Khan ◽  
Farooq A Jan ◽  
Illahay Jalali
Keyword(s):  
Emergency Department ◽  
Rural Areas ◽  
Tertiary Care ◽  
North India ◽  
Care Hospital ◽  
Medical Sciences ◽  
Medicine Department ◽  
Health Practitioners ◽  
Public Health Practitioners ◽  
And Training

Introduction: Poisoning is a common medico-social problem. It is a significant contributor to morbidity and mortality. Knowledge of the epidemiology of poisoning and its changes is important to both emergency physicians and public health practitioners. Our study was to determine the socio-demographic profile, pattern and outcome of the poisoning cases reported to the Emergency Department of a tertiary care hospital. Methods: The study was a Retrospective observational type of study conducted at Sheri-Kashmir Institute of medical sciences, Srinagar J&K.  The patients with acute poisonings presenting to and managed in the Emergency Medicine department between February 2016 to February 2018 were reviewed for inclusion. Data was collected by reviewing records . Using a pre-structured format, case records of poisoning cases were reviewed for gender, age, residence, type of poison, route of poison and outcome of treatment. The collected data was analyzed using descriptive statistical analysis. Results: In the present study the Female: male ratio was 1.9:1 (131 Females and 68 Males).Females outnumbered the males. Highest cases of Poisoning were reported in the age group of 10-20 years. The poisoning in extreme of ages was less observed. Maximum cases of Poisoning belongs to rural areas (60.8%). The most common implicating agents were Pesticides (75.3%). The second common cause of poisoning was drug overdose (20.52%) Maximum cases recovered after treatment (94%). Conclusion: Pattern and magnitude of poisoning are multidimensional and demand multi-sectorial approach for facing this problem. There is a need for stringent pesticide regulation laws and counseling and training programs to reduce the incidence of poisonings. JMS 2018;21(1):24-30

scholarly journals Seroprevalence of syphilis among pregnant females attending antenatal clinic at a tertiary care hospital in North India

2020 ◽  
Vol 8 (2) ◽  
pp. 539
Author(s):  
Noor Jahan ◽  
Swastika Singh Chandel ◽  
Deepak Chopra ◽  
Arshiya Khan ◽  
Razia Khatoon
Keyword(s):  
Rural Areas ◽  
Urban Areas ◽  
Tertiary Care ◽  
Transmitted Disease ◽  
First Trimester ◽  
Antenatal Clinic ◽  
North India ◽  
Care Hospital ◽  
Cross Sectional ◽  
Pregnant Females

Background: Syphilis is a sexually transmitted disease caused by bacteria named Treponema palladium, subsp. pallidum. Nearly 1.36 million pregnant women are known to be affected by syphilis in the developing countries. When left untreated syphilis during pregnancy can result in adverse fetal outcomes such as spontaneous abortion and stillbirth. Objective of the study was present study was done to evaluate the seroprevalence of syphilis among pregnant females attending Antenatal Clinic (ANC).Methods: A hospital based cross-sectional study was done over a period of six months from January to June 2019. A total of 132 pregnant females were included in the study who attended Antenatal Clinic for routine checkup whose blood samples were sent to Microbiology Laboratory for screening for syphilis by Rapid Plasma Reagin (RPR) test.Results: Out of 132 samples of pregnant females screened for syphilis, none of the sample was found reactive for syphilis by RPR test. Maximum patients (57.6%) belonged to age group 20-25 years followed by (27.3%) of 26-30 years. 30.3% patients belonged to urban areas and 69.7% patients belonged to rural areas. Majority of patients (80.3%) belonged to first trimester, followed by (18.9%) patients to second trimester and (0.8%) patients to third trimester. 78.8% patients were from lower socio-economic class followed by 12.9% patients from middle class and 8.3% patients from upper class.Conclusions: Although zero percent syphilis prevalence was observed in this study, it is recommended that free screening for syphilis should be offered to all pregnant females visiting Antenatal Clinic.

scholarly journals Prevalence of Dengue, Chikungunya, and Zika Viruses in Febrile Pregnant Women: An Observational Study at a Tertiary Care Hospital in North India

2021 ◽  
Author(s):  
Akanksha Gupta ◽  
Parul Jain ◽  
Vimala Venkatesh ◽  
Anjoo Agarwal ◽  
D. Himanshu Reddy ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Rural Areas ◽  
Vaginal Bleeding ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Fetal Outcome ◽  
North India ◽  
Care Hospital ◽  
Delivery Outcome ◽  
The Difference

Dengue virus (DENV), chikungunya virus (CHIKV), and Zika virus (ZIKV) are arboviruses that can affect maternal and fetal outcome if acquired during pregnancy. This study was done to estimate the positivity of DENV, CHIKV, and ZIKV in febrile pregnant women attending a tertiary care hospital in north India. Symptomatic pregnant women were tested for these viruses by IgM ELISA and/or by Trioplex real-time polymerase chain reaction. Their symptoms and laboratory parameters were recorded and were followed up till delivery to know their immediate delivery outcome. Of 104 women tested, 50 (48.1%) were positive for viral markers. Of these, evidence of infection by DENV, CHIKV, and both was found in 34 (32.7%), 10 (9.6%), and 6 (5.8%), respectively. ZIKV was not detected in any woman. Maximum DENV positivity occurred in the third trimester of pregnancy and in women residing in urban than rural areas. Chills and rigors, arthralgia, retro-orbital pain, anemia, and vaginal bleeding were more commonly associated with DENV positivity. Backache, arthralgia, jaundice, and vaginal bleeding were more common in CHIKV positives but the difference between positives and nonpositives regarding these symptoms was not statistically significant. Dengue infections were associated with more frequent hospitalizations (OR = 8.38, 95% confidence intervals [CI] = 3.29–21.30) and mortality (OR = 19.0, 95% CI = 1.01–357.10). Hence, to conclude, in India wherever possible, all symptomatic pregnant women should be screened for DENV, CHIKV, and ZIKV as part of sentinel surveillance for ZIKV.

Risk Factors for Infection and Molecular Typing in Patients in the Intensive Care Unit Colonized with NosocomialEnterobacter Aerogenes

2002 ◽  
Vol 23 (8) ◽  
pp. 452-456 ◽  
Author(s):  
Michael Piagnerelli ◽  
Eric Carlier ◽  
Ariane Deplano ◽  
Philippe Lejeune ◽  
Danielle Govaerts
Keyword(s):  
Risk Factors ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Tertiary Care ◽  
Enterobacter Aerogenes ◽  
Care Hospital ◽  
Younger Age ◽  
Infection Risk Factors ◽  
Surgical Icu ◽  
Prolonged Hospital

Objectives:To determine the frequency of colonization byEnterobacter aerogenesin patients in the intensive care unit (ICU) for more than 48 hours and to evaluate the risk factors for infection in patients colonized by this bacteria.Design:An 8-month prospective study.Setting:A 12-bed medical–surgical ICU in a 450-bed, university-affiliated, tertiary-care hospital in Belgium.Method:Pulsed-field gel electrophoresis was used to determine the genotypes ofE. aerogenesisolates.Results:We observed two major clones ofE. aerogenesin the ICU. Interestingly, 87.5% of infected patients had the same genomic profile for colonization and infection. Risk factors for infection in this particular population included younger age, prolonged hospital stay, mechanical ventilation, and bronchoscopy.Conclusions:Colonization is a major prerequisite for infection. The identification of risk factors for infection in colonized patients can optimize the quality of treatment in the ICU.

Delay in initiation of clozapine: A retrospective study from a tertiary care hospital in North India

2015 ◽  
Vol 226 (1) ◽  
pp. 181-185 ◽  
Author(s):  
Sandeep Grover ◽  
Nandita Hazari ◽  
Subho Chakrabarti ◽  
Ajit Avasthi
Keyword(s):  
Retrospective Study ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
North India ◽  
Care Hospital

scholarly journals Seroreactivity of HIV among patients attending a tertiary care hospital in North India: a retrospective analysis

2019 ◽  
Vol 8 (1) ◽  
pp. 177
Author(s):  
Akanksha Singh ◽  
Deepak Chopra ◽  
Sarver Jahan ◽  
Razia Khatoon
Keyword(s):  
Rural Areas ◽  
Hiv Transmission ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Intervention Strategy ◽  
North India ◽  
People Living With Hiv ◽  
Care Hospital ◽  
Immunodeficiency Syndrome ◽  
Hiv Aids

Background: HIV (Human Immunodeficiency Virus) is the causative agent of AIDS (Acquired Immunodeficiency Syndrome). It belongs to the lentivirus subgroup of the family Retroviridae. The HIV/AIDS is spreading worldwide at an alarming rate. India has the third largest number of estimated people living with HIV/AIDS. Most common mode of HIV transmission is through heterosexual contact, blood transfusion, percutaneous, mucosal and perinatal mode. The present study was done to evaluate the seroreactivity of HIV among patients attending Integrated Counselling and Testing Centre (ICTC) of our Tertiary care hospital.  Methods: This retrospective study was conducted on data of patients who had attended ICTC and undergone HIV testing from January 2017 to January 2019. A total of 4519 patients were included in the study who gave their consent followed by pre-test and post-test counseling and were screened for HIV antibody by using rapid kit Comb-Aids.Results: Out of 4519 samples tested, 23 were reactive to HIV screening test, hence sero-reactivity of HIV was found to be 0.50%. Higher seroreactivity was seen among males (56.5%, 13/23), and patients aged 31-40 years (39.1%, 9/23). Maximum seroreactivity was found among patients of rural areas (73.9%, 17/23), indoor patients (91.3%, 21/23) and married patients (73.9%, 17/23).Conclusions: In this study the seroreactivity of HIV was found to be low among patients attending ICTC but still HIV continues to be a major contributor to the global burden of disease. ICTC data can be used as an important tool for planning and improving the national HIV/AIDS intervention strategy.

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