scholarly journals Prevalence of Dengue, Chikungunya, and Zika Viruses in Febrile Pregnant Women: An Observational Study at a Tertiary Care Hospital in North India

2021 ◽  
Author(s):  
Akanksha Gupta ◽  
Parul Jain ◽  
Vimala Venkatesh ◽  
Anjoo Agarwal ◽  
D. Himanshu Reddy ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Rural Areas ◽  
Vaginal Bleeding ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Fetal Outcome ◽  
North India ◽  
Care Hospital ◽  
Delivery Outcome ◽  
The Difference

Dengue virus (DENV), chikungunya virus (CHIKV), and Zika virus (ZIKV) are arboviruses that can affect maternal and fetal outcome if acquired during pregnancy. This study was done to estimate the positivity of DENV, CHIKV, and ZIKV in febrile pregnant women attending a tertiary care hospital in north India. Symptomatic pregnant women were tested for these viruses by IgM ELISA and/or by Trioplex real-time polymerase chain reaction. Their symptoms and laboratory parameters were recorded and were followed up till delivery to know their immediate delivery outcome. Of 104 women tested, 50 (48.1%) were positive for viral markers. Of these, evidence of infection by DENV, CHIKV, and both was found in 34 (32.7%), 10 (9.6%), and 6 (5.8%), respectively. ZIKV was not detected in any woman. Maximum DENV positivity occurred in the third trimester of pregnancy and in women residing in urban than rural areas. Chills and rigors, arthralgia, retro-orbital pain, anemia, and vaginal bleeding were more commonly associated with DENV positivity. Backache, arthralgia, jaundice, and vaginal bleeding were more common in CHIKV positives but the difference between positives and nonpositives regarding these symptoms was not statistically significant. Dengue infections were associated with more frequent hospitalizations (OR = 8.38, 95% confidence intervals [CI] = 3.29–21.30) and mortality (OR = 19.0, 95% CI = 1.01–357.10). Hence, to conclude, in India wherever possible, all symptomatic pregnant women should be screened for DENV, CHIKV, and ZIKV as part of sentinel surveillance for ZIKV.

scholarly journals Comparison of gel test and conventional tube test for antibody detection and titration in D-negative pregnant women: study from a tertiary-care hospital in North India

2020 ◽  
Vol 26 (4) ◽  
pp. 174-177
Author(s):  
Manish K. Thakur ◽  
Neelam Marwaha ◽  
Praveen Kumar ◽  
Subhash C. Saha ◽  
Beenu Thakral ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
North India ◽  
Antibody Detection ◽  
Care Hospital ◽  
Tube Test

“PREVALENCE OF ABNORMAL CERVICAL CYTOLOGY IN ANTENATAL WOMEN BY LIQUID BASED CYTOLOGY IN A TERTIARY CARE HOSPITAL IN NORTH INDIA”

2021 ◽  
pp. 48-50
Author(s):  
Ankita Ankita ◽  
Vijay Zutshi ◽  
Mukul Singh
Keyword(s):  
Pregnant Women ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Cervical Cytology ◽  
North India ◽  
Low Grade ◽  
Care Hospital ◽  
Abnormal Cervical Cytology ◽  
Intraepithelial Lesion ◽  
Liquid Based Cytology

Background: This study aimed to know the prevalence of abnormal cervical cytology in pregnant women by liquid-based cytology (LBC). Materials and Methods : Cross sectional study done at a tertiary care hospital in between August 2017 to January 2019.Six hundred pregnant women attending the OPD at their rst visit were enrolled and after taking consent, history and clinical examination , subjected to cervical cancer screening by LBC. Result: Out of 600 samples, 10 samples (1.67%) were unsatisfactory for evaluation due to low cellularity. Among 590 samples, only 2 reported as LSIL(Low grade squamous intraepithelial lesion) and 588 reported as NILM (Negative for intraepithelial lesion or malignancy). Inammation of varying degree, mild, moderate and dense was reported in 58.65%, 24.92% and 16.44% respectively. Infection was reported in 3.73% and Candida. Discussion: prevalence of abnormal cervical cytology among pregnant women in region was low but screening for cancer cervix should be done for all pregnant women, adverse pregnancy outcomes like premature rupture of membranes, preterm birth and low birth weight.

scholarly journals Seroreactivity of HIV among patients attending a tertiary care hospital in North India: a retrospective analysis

2019 ◽  
Vol 8 (1) ◽  
pp. 177
Author(s):  
Akanksha Singh ◽  
Deepak Chopra ◽  
Sarver Jahan ◽  
Razia Khatoon
Keyword(s):  
Rural Areas ◽  
Hiv Transmission ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Intervention Strategy ◽  
North India ◽  
People Living With Hiv ◽  
Care Hospital ◽  
Immunodeficiency Syndrome ◽  
Hiv Aids

Background: HIV (Human Immunodeficiency Virus) is the causative agent of AIDS (Acquired Immunodeficiency Syndrome). It belongs to the lentivirus subgroup of the family Retroviridae. The HIV/AIDS is spreading worldwide at an alarming rate. India has the third largest number of estimated people living with HIV/AIDS. Most common mode of HIV transmission is through heterosexual contact, blood transfusion, percutaneous, mucosal and perinatal mode. The present study was done to evaluate the seroreactivity of HIV among patients attending Integrated Counselling and Testing Centre (ICTC) of our Tertiary care hospital.  Methods: This retrospective study was conducted on data of patients who had attended ICTC and undergone HIV testing from January 2017 to January 2019. A total of 4519 patients were included in the study who gave their consent followed by pre-test and post-test counseling and were screened for HIV antibody by using rapid kit Comb-Aids.Results: Out of 4519 samples tested, 23 were reactive to HIV screening test, hence sero-reactivity of HIV was found to be 0.50%. Higher seroreactivity was seen among males (56.5%, 13/23), and patients aged 31-40 years (39.1%, 9/23). Maximum seroreactivity was found among patients of rural areas (73.9%, 17/23), indoor patients (91.3%, 21/23) and married patients (73.9%, 17/23).Conclusions: In this study the seroreactivity of HIV was found to be low among patients attending ICTC but still HIV continues to be a major contributor to the global burden of disease. ICTC data can be used as an important tool for planning and improving the national HIV/AIDS intervention strategy.

scholarly journals Clinical profile, maternal and fetal outcome in pregnant women with COVID-19 infection: a retrospective observational study in a tertiary care hospital of Himachal Pradesh

2020 ◽  
Vol 10 (1) ◽  
pp. 228
Author(s):  
Poojan Dogra ◽  
B. R. Sharma ◽  
Shuchi Sharma ◽  
Reena Sharma
Keyword(s):  
Pregnant Women ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Age Groups ◽  
Fetal Outcome ◽  
Himachal Pradesh ◽  
Care Hospital ◽  
Management Guidelines ◽  
Disease Symptoms ◽  
Cure Rates

Background: The aim of this study was to evaluate the clinical characteristics and outcomes of pregnant women confirmed with COVID-19 infections and their neonates to provide more reference to contribute in managing this noval viral disease.Methods: We conducted a retrospective study over a period of six months; 20 March, 2020 to 8 October, 2020 at SLBSGMC Nerchowk (Himachal Pradesh). Total number of pregnant women who delivered in our hospital during the defined study period was recorded and analysed.Results: The total number of women were delivered over the study period was 13, out of which caesarean sections (CS) were 7 and NVDs were 6 in number. All of them were diagnosed mild COVID-19, and none one of the patients developed severe COVID-19 or died. Their all newborns were recorded healthy except one was COVID positive and one neonate had birth asphyxia.Conclusions: Apparently no difference was observed in relation to onset of disease, symptoms, cure rates or severity in pregnant women when compared to non-pregnant women and healthy men of similar age groups. Pregnancy does not seem to deteriorate the course and prognosis of the disease. Maternal and fetal outcomes are apparently favourable in these patients. Lastly COVID-19 is not an indication of cesarean section. More multicentre studies are the need of the hour to formulate the authentic management guidelines for this novel disease.

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