scholarly journals Vascular Network Imaging on Whole‐Mount Mouse Dura Mater with Cranial Bone

2021 ◽  
Vol 35 (S1) ◽  
Author(s):  
Leike Xie ◽  
Sunilima Sinha ◽  
Vladislav Glinsky ◽  
Kannappan Palaniappan ◽  
Olga Glinskii
2020 ◽  
Vol 3 (3) ◽  
pp. 17-26
Author(s):  
Quenum K ◽  
Fatigba Oh ◽  
Houndje Yp ◽  
Tchegnonsi C ◽  
Alihonou T ◽  
...  

Introduction The extra dural hematoma is a blood collection between the cranial vault and the dura mater. It is a neurosurgical emergency whose statistical data are poorly known in the Republic of Benin. Objective The aims of this study are to assess epidemiology, therapeutic and outcome of traumatic extra dural hematomas for children admitted to the surgical department of CHUD-B/A from 2012 to 2017. Methods This was a cross-sectional, descriptive and retrospective study over a period from January 1st, 2012 to December 31st, 2017. Results One hundred and seventy-eight cases of children aged between 0-15 years were examined for brain traumatic injury. Twenty-seven 27 (15.2%) cases of extra dural hematomas were retained. The most represented age group was between 11-15 years with a frequency of 42.1%. The male sex was more represented (78.9%). Road traffic accidents were the main aetiology (57.9%). 52.6% had a mild head injury, 26.3% had a moderate head injury and 21.1% had a severe head injury. On brain scan the frequently observed location was temporo-parietal (31.6%). Acute anemia was observed in 16 children. Seventeen children were operated on. The operation involved evacuation of extra dural hematoma by cranial bone flap with suspension of the dura mater. There were no deaths. Conclusion The availability of brain CT makes the diagnosis of extra dural hematoma easier. Its management is neurosurgical with a favourable post-operative evolution in all cases in this series.


2015 ◽  
Vol 26 (2) ◽  
pp. 368-372
Author(s):  
Bao Nan ◽  
Yang Bo ◽  
Song Yun-Hai ◽  
Chen Cheng ◽  
Mu Xiong-Zheng

Author(s):  
Lassana Cissé ◽  
Salimata Diarra ◽  
Abdoulaye Yalcouyé ◽  
Youlouza Coulibaly ◽  
Abdoulaye Tamega ◽  
...  

Acalvaria is a rare and lethal congenital malformation characterized by the absence of the cranial vault bones, dura mater and associated muscles with complete cranial content. We report a 5-year-old Malian girl seen at 20 months old for facial dysmorphia, hemiparesis, and a cranial bone defect that improved progressively.


2010 ◽  
Vol 25 (3) ◽  
pp. 264-268 ◽  
Author(s):  
André de Mendonça Costa ◽  
Gerson Shigeru Kobayashi ◽  
Daniela Franco Bueno ◽  
Marília Trierveiler Martins ◽  
Marcus de Castro Ferreira ◽  
...  

PURPOSE: To develop an experimental surgical model in rats for the study of craniofacial abnormalities. METHODS: Full thickness calvarial defects with 10x10-mm and 5x8-mm dimensions were created in 40 male NIS Wistar rats, body weight ranging from 320 to 420 g. The animals were equally divided into two groups. The periosteum was removed and dura mater was left intact. Animals were killed at 8 and 16 weeks postoperatively and cranial tissue samples were taken from the defects for histological analysis. RESULTS: Cranial defects remained open even after 16 weeks postoperatively. CONCLUSION: The experimental model with 5x8-mm defects in the parietal region with the removal of the periosteum and maintenance of the integrity of the dura mater are critical and might be used for the study of cranial bone defects in craniofacial abnormalities.


2006 ◽  
Vol 17 (3) ◽  
pp. 584-590 ◽  
Author(s):  
Mikako Takagi ◽  
Kensuke Kiyokawa ◽  
Aritaka Sakamoto ◽  
Kouichi Watanabe ◽  
Hideaki Rikimaru ◽  
...  

2018 ◽  
Vol 6 (2) ◽  
pp. 372-375
Author(s):  
Slavomir Kondoff ◽  
Atanas Drenchev ◽  
Torello Lotti ◽  
Uwe Wollina ◽  
Ilia Lozev ◽  
...  

BACKGROUND: Basal cell carcinomas (BCC) located in the sun-exposed regions are a serious therapeutic challenge. Therefore early diagnosis and adequate therapy should be of a high priority for every dermatologic surgeon.CASE PRESENTATION: We are presenting a patient with multiple BCCs, located on the area of the scalp, who had been treated several years ago with electrocautery and curettage after histopathological verification. However, the last few years the tumours have advanced, infiltrating firstly the tabula external and a year later the tabula interna of the cranium. A computed -tomography (CT) imaging and radiography of the skull were performed to reveal the definite tumour localisation, needed for planning an one - step surgical intervention. Both of the instrumental examinations confirmed the existence of osteolytic tumour lesions. Craniotomy with precise removal of the BCCs infiltrating the cranial bone in all of its thickness was performed. Partial resection of dura mater was also performed also because intraoperative findings established the involvement of the dura. Histopathological verification revealed bone and dural invasion with clean resection margins. The bone defect was recovered with hydroxyapatite cement. Reconstruction as the shape of the skull was carefully modified and adapted to its initial size and form. Layered closure of the skin and soft tissues were performed after the complete removal of the BCCs. The postoperative period had no serious complications.CONCLUSION: Precisely managed therapy of BCC is curative in most of the cases as it ensures good prognosis for the patient.


2020 ◽  
Vol 25 (2) ◽  
pp. 21 ◽  
Author(s):  
Mohammad Hosseini-Farid ◽  
MaryamSadat Amiri-Tehrani-Zadeh ◽  
Mohammadreza Ramzanpour ◽  
Mariusz Ziejewski ◽  
Ghodrat Karami

Knowing the precise material properties of intracranial head organs is crucial for studying the biomechanics of head injury. It has been shown that these biological tissues are significantly rate-dependent; hence, their material properties should be determined with respect to the range of deformation rate they experience. In this paper, a validated finite element human head model is used to investigate the biomechanics of the head in impact and blast, leading to traumatic brain injuries (TBI). We simulate the head under various directions and velocities of impacts, as well as helmeted and unhelmeted head under blast shock waves. It is demonstrated that the strain rates for the brain are in the range of 36 to 241 s−1, approximately 1.9 and 0.86 times the resulting head acceleration under impacts and blast scenarios, respectively. The skull was found to experience a rate in the range of 14 to 182 s−1, approximately 0.7 and 0.43 times the head acceleration corresponding to impact and blast cases. The results of these incident simulations indicate that the strain rates for brainstem and dura mater are respectively in the range of 15 to 338 and 8 to 149 s−1. These findings provide a good insight into characterizing the brain tissue, cranial bone, brainstem and dura mater, and also selecting material properties in advance for computational dynamical studies of the human head.


2015 ◽  
Vol 10 (7) ◽  
pp. 1101
Author(s):  
Byung-Cheon Lee ◽  
KiBog Lee ◽  
Ho-Sung Lee ◽  
Dai-In Kang ◽  
SeungZhoo Yoon ◽  
...  

2004 ◽  
Vol 215 (2) ◽  
pp. 139-148 ◽  
Author(s):  
F. PLOURABOUE ◽  
P. CLOETENS ◽  
C. FONTA ◽  
A. STEYER ◽  
F. LAUWERS ◽  
...  

Author(s):  
E. T. O'Toole ◽  
R. R. Hantgan ◽  
J. C. Lewis

Thrombocytes (TC), the avian equivalent of blood platelets, support hemostasis by aggregating at sites of injury. Studies in our lab suggested that fibrinogen (fib) is a requisite cofactor for TC aggregation but operates by an undefined mechanism. To study the interaction of fib with TC and to identify fib receptors on cells, fib was purified from pigeon plasma, conjugated to colloidal gold and used both to facilitate aggregation and as a receptor probe. Described is the application of computer assisted reconstruction and stereo whole mount microscopy to visualize the 3-D organization of fib receptors at sites of cell contact in TC aggregates and on adherent cells.Pigeon TC were obtained from citrated whole blood by differential centrifugation, washed with Ca++ free Hank's balanced salts containing 0.3% EDTA (pH 6.5) and resuspended in Ca++ free Hank's. Pigeon fib was isolated by precipitation with PEG-1000 and the purity assessed by SDS-PAGE. Fib was conjugated to 25nm colloidal gold by vortexing and the conjugates used as the ligand to identify fib receptors.


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