scholarly journals β‐Carotene and vitamin E supplementation on immunity and oxidative status in geriatric dogs

2007 ◽  
Vol 21 (5) ◽  
Author(s):  
Jean Soon Park ◽  
Michael G. Hayek ◽  
Gregory A. Reinhart ◽  
Stefan Massimino ◽  
Boon P. Chew
Meat Science ◽  
2002 ◽  
Vol 60 (1) ◽  
pp. 35-40 ◽  
Author(s):  
A Yang ◽  
M.J Brewster ◽  
M.C Lanari ◽  
R.K Tume

2015 ◽  
Vol 18 (2) ◽  
pp. 299-305 ◽  
Author(s):  
M. Szczubiał

Abstract The effect of vitamins E, C and β-carotene supplementation in sows on the parameters of antioxidative/oxidative status during the postpartum period was investigated. Twenty four primiparous sows, divided into two groups (experimental and control), were included in the study. After the half-way point of pregnancy until farrowing, each experimental sow received feed supplemented twice a week with 200 mg of vitamin E and 1000 mg of vitamin C, and additionally, 70 mg of β-carotene were administered via intramuscular injection, on day 14 and day 7 before farrowing. The control group was not supplemented. Blood samples were collected before supplementation (gestational day 57-58), 48 hours and 7 days after parturition. The following antioxidative and oxidative parameters were measured using spectrophotometric methods: glutathione peroxidase (GSH-Px), superoxide dismutase (SOD), catalase (CAT), vitamin C, vitamin E, thiobarbituric acid reactive substances (TBARS), and sulfhydryl groups (SH groups). In supplemented sows the erythrocyte activity of GSH-Px and CAT was found to be significantly higher on day 7 after farrowing and the activity of SOD was significantly higher at 48 hours postpartum, compared to the control group. The concentration of vitamins C and E in plasma of the supplemented group was found to be significantly higher and the content of TBARS was found significantly lower at both postpartum measurement points, compared to the control group. The content of SH groups was significantly higher on day 7 postpartum, compared to the control group. The study findings indicate that supplementation of pregnant sows with vitamins E, C and β-carotene in the second half of pregnancy has beneficial effects on the antioxidative/oxidative balance in the postpartum period by increasing the antioxidative potential and reducing lipid and protein peroxidation.


2010 ◽  
Vol 62 (3) ◽  
pp. 677-681 ◽  
Author(s):  
S.F. Djurasevic ◽  
Jelena Djordjevic ◽  
N. Jasnic ◽  
Iva Lakic ◽  
P. Vujovic ◽  
...  

We tested to see if the additional intake of vitamin E in the form of ?-tocopheryl-succinate would improve liver antioxidative protection. Thus, we studied the tissue oxidative status in rats supplemented by two doses of the antioxidant over a four week period of time. Our results confirmed that the additional intake of vitamin E decreased the liver lipid peroxidation level and SOD activity level and preserved its vitamin C content. However, the hydrogen peroxide content and catalase activity remained unchanged, probably due to the mechanism of vitamin E liver metabolism. .


2008 ◽  
Vol 100 (4) ◽  
pp. 896-902 ◽  
Author(s):  
Harri Hemilä ◽  
Jaakko Kaprio

Vitamin E and β-carotene affect the immune function and might influence the predisposition of man to infections. To examine whether vitamin E or β-carotene supplementation affects tuberculosis risk, we analysed data of the Alpha-Tocopherol Beta-Carotene Cancer Prevention (ATBC) Study, a randomised controlled trial which examined the effects of vitamin E (50 mg/d) and β-carotene (20 mg/d) on lung cancer. The trial was conducted in the general community in Finland in 1985–93; the intervention lasted for 6·1 years (median). The ATBC Study cohort consists of 29 023 males aged 50–69 years, smoking at baseline, with no tuberculosis diagnosis prior to randomisation. Vitamin E supplementation had no overall effect on the incidence of tuberculosis (risk ratio (RR) = 1·18; 95 % CI 0·87, 1·59) nor had β-carotene (RR = 1·07; 95 % CI 0·80, 1·45). Nevertheless, dietary vitamin C intake significantly modified the vitamin E effect. Among participants who obtained 90 mg/d or more of vitamin C in foods (n13 502), vitamin E supplementation increased tuberculosis risk by 72  (95 % CI 4, 185)%. This effect was restricted to participants who smoked heavily. Finally, in participants not supplemented with vitamin E, dietary vitamin C had a negative association with tuberculosis risk so that the adjusted risk was 60 (95 % CI 16, 81) % lower in the highest intake quartile compared with the lowest. Our finding that vitamin E seemed to transiently increase the risk of tuberculosis in those who smoked heavily and had high dietary vitamin C intake should increase caution towards vitamin E supplementation for improving the immune system.


2005 ◽  
Vol 135 (10) ◽  
pp. 2457-2461 ◽  
Author(s):  
Yih-Fwu Lin ◽  
Hsiu-Ling Tsai ◽  
Yi-Chun Lee ◽  
Sue-Joan Chang

2010 ◽  
Vol 90 (2) ◽  
pp. 197-202 ◽  
Author(s):  
A. Schiavone ◽  
J. Nery ◽  
J A Choque-López ◽  
M D Baucells ◽  
A C Barroeta

The present work aimed to assess: (1) whether the oxidative status of dietary lipids or vitamin E supplementation influences in vivo erythrocyte integrity of chickens, and (2) whether erythrocyte stability is related to musculus iliotibialis susceptibility to lipid peroxidation. Thirty-six broilers were fed a basal diet supplemented with: sunflower oil (SO), sunflower oil and α-tocopheryl acetate (SO + E), and oxidized sunflower oil (SO-OX). In vivo hemolysis rate (HR) and thiobarbituric acid reactive substances (TBARS) of erythrocytes were measured. Postmortem, the TBARS of m. iliotibialis was determined. Erythrocyte HR and TBARS were higher in SO-OX than SO and SO + E groups (P < 0.001). Erythrocyte and muscle TBARS were highly correlated (r2 > 0.93). The SO-OX induced negative effects, indicating that dietary lipid quality is rapidly translated in negative effects to erythrocytes and muscle. In vivo erythrocyte TBARS proved to be a good indicator of meat oxidative status. Key words: Broiler, vitamin E, lipid oxidation, TBARS, erythrocytes, hemolysis


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