scholarly journals Increased body mass index adversely affects dyslipidemias, blood pressure and inflammation in men and women with metabolic syndrome (LB365)

2014 ◽  
Vol 28 (S1) ◽  
Author(s):  
Catherine Andersen ◽  
David Aguilar ◽  
Jennifer Jones ◽  
Christopher Blesso ◽  
Taif Al‐Sarraj ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Body Mass Index ◽  
Body Mass ◽  
Men And Women

scholarly journals The effects of metformin plus sulfonylurea therapy on clinical features of the metabolic syndrome

2010 ◽  
Vol 63 (9-10) ◽  
pp. 611-615 ◽  
Author(s):  
Branka Koprivica ◽  
Teodora Beljic-Zivkovic ◽  
Tatjana Ille
Keyword(s):  
Insulin Resistance ◽  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Metabolic Syndrome ◽  
Body Mass Index ◽  
Waist Circumference ◽  
Glycemic Control ◽  
Body Mass ◽  
Combined Therapy

Introduction. Insulin resistance is a well-known leading factor in the development of metabolic syndrome. The aim of this study was to evaluate metabolic effects of metformin added to sulfonylurea in unsuccessfully treated type 2 diabetic patients with metabolic syndrome. Material and methods. A group of thirty subjects, with type 2 diabetes, secondary sulfonylurea failure and metabolic syndrome were administered the combined therapy of sulfonylurea plus metformin for six months. Metformin 2000 mg/d was added to previously used sulfonylurea agent in maximum daily dose. Antihypertensive and hypolipemic therapy was not changed. The following parameters were assessed at the beginning and after six months of therapy: glycemic control, body mass index, waist circumference, blood pressure, triglycerides, total cholesterol and its fractions, homeostatic models for evaluation of insulin resistance and secretion (HOMA R, HOMA B) and C- peptide. Results. Glycemic control was significantly improved after six months of the combined therapy: (fasting 7.89 vs. 10.61 mmol/l. p<0.01; postprandial 11.12 vs. 12.61 mmol/l. p<0.01, p<0.01; glycosylated hemoglobin 6.81 vs. 8.83%. p<0.01). the body mass index and waist circumference were significantly lower (26.7 vs. 27.8 kg/m2, p<0.01 and 99.7 vs. 101.4 cm for men, p<0.01; 87.2 vs. 88.5 for women, p<0.01). Fasting plasma triglycerides decreased from 3.37 to 2.45 mmol/l (p<0.001) and HOMA R from 7.04 to 5.23 (p<0.001). No treatment effects were observed on blood pressure, cholesterol, and residual insulin secretion. Conclusion. Administration of metformin in type 2 diabetes with metabolic syndrome decreased cardiovascular risk factors by reducing glycemia, triglycerides, BMI, central obesity and insulin resistance.

Body mass index and blood pressure in Korean men and women

1994 ◽  
Vol 12 (12) ◽  
pp. 1433 ◽  
Author(s):  
Daniel W. Jones ◽  
Joung S. Kim ◽  
Michael E. Andrew ◽  
Sung J. Kim ◽  
Young P. Hong
Keyword(s):  
Blood Pressure ◽  
Body Mass Index ◽  
Body Mass ◽  
Men And Women

scholarly journals Testosterone: Relationships with Metabolic Disorders in Men—An Observational Study from SPECT-China

2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Jing Cheng ◽  
Bing Han ◽  
Qin Li ◽  
Fangzhen Xia ◽  
Hualing Zhai ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Body Mass Index ◽  
Body Mass ◽  
Weight Status ◽  
Metabolic Disorders ◽  
Metabolic Parameters ◽  
Total Testosterone ◽  
Logistic Regressions ◽  
Obesity Indices

Background. The strength of associations between total testosterone (TT) and metabolic parameters may vary in different nature of population structure; however, no study has ever given this information in Chinese population, especially those without metabolic syndrome (MS). We aimed to analyze the association magnitudes between TT and multiple metabolic parameters in general Chinese men. Methods. 4309 men were recruited from SPECT-China study in 2014-2015, which was performed in 22 sites in East China. TT, weight status, and various metabolic parameters were measured. Linear and logistic regressions were used to analyze the associations. Results. Men in lower TT quartiles had worse metabolic parameters including body mass index, triglycerides, HbA1c, and HOMA-IR (all P for trend < 0.001). Body mass index (B −0.32, 95%CI −0.35 to −0.29) and obesity (OR 0.40, 95%CI 0.35–0.45) had the largest association magnitude per one SD increment in TT, while blood pressure and hypertension (OR 0.90, 95%CI 0.84–0.98) had the smallest. These associations also persisted in individuals without metabolic syndrome. Conclusions. Obesity indices had closer relationships with TT than most other metabolic measures with blood pressure the least close. These associations remained robust after adjustment for adiposity and in subjects without metabolic syndrome.

scholarly journals Relationship Between Physical Fitness, BMI, WHR and Hypertension in Elderly Men and Women

2013 ◽  
Vol 52 (4) ◽  
pp. 275-284
Author(s):  
Saša Pantelić ◽  
Radmila Kostić ◽  
Ratomir Djurašković ◽  
Slavoljub Uzunović ◽  
Zoran Milanović ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Body Mass Index ◽  
Physical Fitness ◽  
Body Mass ◽  
Elderly Women ◽  
Upper Body ◽  
Predictor Variables ◽  
Elderly Men ◽  
Men And Women ◽  
Arterial Blood

Abstract Aim: The aim of this study was to determine the structure, characteristics and significance of the relationship between physical fitness, BMI and WHR on one hand and hypertension of elderly men and women on the other. Methods: The sample consisted of 1288 participants (594 men and 694 women) who live in their own households in the cities and villages of Central, Eastern and South Serbia. After the obtained classification of participants based on arterial blood pressure, 231 patients with hypertension aged 60-80 years were selected. The subsample consisted of 138 male participants, while the subsample of women was 93 participants. Predictor variables consisted of 6 variables for the evaluation of physical fitness, Body mass index (BMI) and Waist-to Hip Ratio index (WHR). Criterion variables consisted of systolic blood pressure (SBP) and diastolic blood pressure (DBP). Results: The results showed that there is a statistically significant correlation (p <0.05) between predictor variables and hypertension. Higher values of higher SBP in elderly men causes an increase in body weight due to increased body fat (BMI, WHR). In elderly women, these changes occur under the influence of increased body mass index and reduced CRF. Higher values of high DBP in elderly men cause more power and flexibility of the upper body and in elderly women greater strength in the arms and less strength in legs and CRF. Conclusions: Being overweight in both subsamples could be considered as a factor that contributes to high blood pressure.

scholarly journals Fasting alters the gut microbiome reducing blood pressure and body weight in metabolic syndrome patients

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
András Maifeld ◽  
Hendrik Bartolomaeus ◽  
Ulrike Löber ◽  
Ellen G. Avery ◽  
Nico Steckhan ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Body Mass Index ◽  
T Cells ◽  
Regulatory T Cells ◽  
Systolic Blood Pressure ◽  
Body Mass ◽  
Gut Microbiome ◽  
Effector T Cells ◽  
Pharmacological Intervention

AbstractPeriods of fasting and refeeding may reduce cardiometabolic risk elevated by Western diet. Here we show in the substudy of NCT02099968, investigating the clinical parameters, the immunome and gut microbiome exploratory endpoints, that in hypertensive metabolic syndrome patients, a 5-day fast followed by a modified Dietary Approach to Stop Hypertension diet reduces systolic blood pressure, need for antihypertensive medications, body-mass index at three months post intervention compared to a modified Dietary Approach to Stop Hypertension diet alone. Fasting alters the gut microbiome, impacting bacterial taxa and gene modules associated with short-chain fatty acid production. Cross-system analyses reveal a positive correlation of circulating mucosa-associated invariant T cells, non-classical monocytes and CD4+ effector T cells with systolic blood pressure. Furthermore, regulatory T cells positively correlate with body-mass index and weight. Machine learning analysis of baseline immunome or microbiome data predicts sustained systolic blood pressure response within the fasting group, identifying CD8+ effector T cells, Th17 cells and regulatory T cells or Desulfovibrionaceae, Hydrogenoanaerobacterium, Akkermansia, and Ruminococcaceae as important contributors to the model. Here we report that the high-resolution multi-omics data highlight fasting as a promising non-pharmacological intervention for the treatment of high blood pressure in metabolic syndrome patients.

scholarly journals 937. Factors Associated with Metabolic Syndrome in People with HIV under 40 Years in Guatemala

2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S502-S502
Author(s):  
Hugo E Marroquín ◽  
Dean Ortiz ◽  
Lindsey Larson ◽  
Katherine Franco ◽  
Andrej Spec ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Body Mass Index ◽  
Waist Circumference ◽  
Body Mass ◽  
Fasting Glucose ◽  
Cd4 Count ◽  
Group Differences ◽  
P Value ◽  
Low Hdl

Abstract Background HIV infection and antiretroviral therapy (ART) can lead to metabolic abnormalities associated with increased cardiovascular disease risk, some of these abnormalities (central obesity, elevated fasting glucose, triglycerides, and blood pressure and low HDL cholesterol) are in metabolic syndrome (MetS). The prevalence of MetS increases with age. Currently, the status of MetS in people with HIV (PWH) Guatemala is unknown. We assessed the prevalence of MetS and potential predictors in PWH participating in prospective cohort study at Hospital Roosevelt in Guatemala City. Methods We performed a cross-sectional analysis of PWH under 40 years old receiving ART for at least 6 months from July 2019 to March 2020. The harmonized criteria for MetS and the cut-off for waist circumference recommended by the Latin American Diabetes Association were used. Association between MetS and gender, place of residency, ethnicity, educational level, baseline and current CD4 count, smoking, alcohol consumption, physical activity, viral load, body mass index (BMI) and ART exposure was assessed in bivariate analysis. Potential predictors (p-value &lt; 0.1) were included in a multivariate binary logistic regression model. Results Of total cohort of 757 participants enrolled390 (51.5%) were younger than 40 years. Of those under &lt; 40 years, 150 (38.5%) were women, 59 (15.1%) Mayan, median age was 32 years (IQR 27, 37). 93 (23.8%) had MetS. Between group differences in Table 1. Of those with Met, 51 (54.8%) had elevated waist circumference, 87 (93.5%) elevated triglycerides, 83 (89.2%) low HDL-c, 56 (60.2%) elevated blood pressure and 35 (37.6%) elevated fasting glucose. Body mass index (BMI) ≥ 25 kg/m2 or higher and 2 years or more of cumulative non-nucleoside reverse transcription inhibitors (NNRTI) where more common in those &lt; 40 years with MetS compared to those without MetS. On multivariable regression, MetS was associated with current CD4 count &lt; 200 (OR 3.1; IC 1.51, 6.34; p-value &lt; 0.01) and BMI ≥ 25 kg/m2 (OR; 6.53; IC 3.64, 11.73; p-value &lt; 0.01). Table1. Between group differences (No MetS vs MetS) Conclusion Nearly one in every four PWH under 40 years old in our cohort was affected by MetS. Dyslipidemia (elevated triglycerides and low HDL-c) was the main driver of MetS. Lower CD4 count and overweight were predictors for MetS in PWH under 40. Disclosures Andrej Spec, MD, MSCI, Astellas (Grant/Research Support)Mayne (Consultant)Scynexis (Consultant)

scholarly journals PERBAIKAN LINGKAR PERUT, TEKANAN DARAH, DAN BODY MASS INDEX WANITA SINDROM METABOLIK MENGGUNAKAN YOGURT SUSU KECAMBAH KACANG MERAH

2020 ◽  
Vol 4 (2) ◽  
pp. 173
Author(s):  
Hery Winarsi ◽  
Aisyah Tri Septiana ◽  
Avia Roselina
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Body Mass Index ◽  
Body Mass ◽  
Skim Milk ◽  
Kidney Bean ◽  
Abdominal Circumference ◽  
Before And After ◽  
Red Kidney Bean ◽  
Red Bean

This study aims to determine the effect of red kidney bean sprout milk yogurt (Rides-Yo) on abdominal circumference, blood pressure, and body mass index of metabolic syndrome women. Red kidney bean sprouts milk added with 10% sucrose and 10% skim milk pasteurized at 70 ° C for 10 minutes, then cooled to 45oC. Inoculated with lactic acid bacteria 2% of the total volume of red bean milk, incubated at 27-35oC for 24 hours. As many as 30 women, 40-65 years aged, central obesity, hypertension, and hyperlipidemia, live in the Baturraden subdistrict, Banyumas Regency, and are willing to sign informed consent. Subjects were randomly divided into 3 groups; the first group was given Rides-Yo; the second group was given a placebo; and group 3 took medicine from a doctor. A total of 200 mL/day of Rides-Yo or placebo was given to the subjects for 2 months. Before and after the intervention, subjects were measured for abdominal circumference, blood pressure, weight and height. There was a decrease in abdominal circumference (P=0,018), systole and diastolic blood pressure (P <0.038 and P=0,032), and BMI (P=0,039) in the group receiving Rides-Yo, compared to placebo and control groups. Thus, Rides-Yo is able to improve the health status of women with metabolic syndrome.  

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