scholarly journals Delta‐tocotrienol Mediates the Cellular Response to Radiation‐Induced DNA Damage through Upregulation of Anti‐Apoptotic Effectors in Human Lung Fibroblast Cell Lines

2015 ◽  
Vol 29 (S1) ◽  
Author(s):  
Kelly Folkers ◽  
Merriline Satyamitra ◽  
Venkataraman Srinivasan
Keyword(s):  
Dna Damage ◽  
Cell Lines ◽  
Cellular Response ◽  
Human Lung ◽  
Fibroblast Cell ◽  
Lung Fibroblast ◽  
Human Lung Fibroblast ◽  
Radiation Induced ◽  
Fibroblast Cell Lines

scholarly journals The role of oxidative stress in 63 T-induced cytotoxicity against human lung cancer and normal lung fibroblast cell lines

2018 ◽  
Vol 37 (5) ◽  
pp. 849-864 ◽  
Author(s):  
Malgorzata Kucinska ◽  
Helena Mieszczak ◽  
Hanna Piotrowska-Kempisty ◽  
Mariusz Kaczmarek ◽  
Walter Granig ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Lung Cancer ◽  
Cell Lines ◽  
Human Lung ◽  
Fibroblast Cell ◽  
Lung Fibroblast ◽  
Human Lung Cancer ◽  
Normal Lung ◽  
Fibroblast Cell Lines

Proliferative Properties and Cytokine Secretion of Lung Fibroblast Cell Lines of the Patients with Idiopathic Pulmonary Fibrosis

1998 ◽  
Vol 45 (1) ◽  
pp. 128
Author(s):  
Dong Soon Kim ◽  
Sang Hoon Paik ◽  
Kyung Yup Kong ◽  
Dong Kwan Kim ◽  
Seong Il Park ◽  
...  
Keyword(s):  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
Cell Lines ◽  
Fibroblast Cell ◽  
Lung Fibroblast ◽  
Cytokine Secretion ◽  
Fibroblast Cell Lines

scholarly journals Antiproliferative Effects of a Series of Pyrazolines on Lung Cancer

Proceedings ◽  
2018 ◽  
Vol 2 (25) ◽  
pp. 1574
Author(s):  
Belgin Sever ◽  
Mehlika Dilek Altıntop ◽  
Elif Kaya Tilki ◽  
Miriş Dikmen ◽  
Ahmet Özdemir
Keyword(s):  
Lung Cancer ◽  
Anticancer Agents ◽  
Human Lung ◽  
Fibroblast Cell ◽  
Inhibitory Effect ◽  
Cytotoxic Effects ◽  
Human Lung Fibroblast ◽  
Antiproliferative Effects ◽  
Ic50 Value ◽  
Fibroblast Cell Lines

Lung cancer is one of the most diagnosed cancers worldwide and the development of anticancer agents for the treatment of lung cancer is an important task for researchers. For this purpose, herein pyrazoline-based compounds 1–18 were investigated for their cytotoxic effects on A549 human lung adenocarcinoma and CCD-19Lu human lung fibroblast cell lines using MTT assay. According to the results, 1-(4-methoxyphenyl)-3-(2-furanyl)-5-(4-methylphenyl)-2-pyrazoline (7) was identified as the most promising anticancer agent due to its selective inhibitory effect on A549 cell line with an IC50 value of 138.63 µg/mL when compared with cyclophosphamide (IC50 = 309.97 µg/mL).

scholarly journals Essential Oil Content of the Rhizome ofCurcuma purpurascensBl. (Temu Tis) and Its Antiproliferative Effect on Selected Human Carcinoma Cell Lines

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Sok-Lai Hong ◽  
Guan-Serm Lee ◽  
Syarifah Nur Syed Abdul Rahman ◽  
Omer Abdalla Ahmed Hamdi ◽  
Khalijah Awang ◽  
...  
Keyword(s):  
Human Lung ◽  
Carcinoma Cell ◽  
Fibroblast Cell ◽  
Lung Fibroblast ◽  
Fibroblast Cell Line ◽  
Human Carcinoma ◽  
Human Lung Fibroblast ◽  
Carcinoma Cell Lines ◽  
Lung Fibroblast Cell Line ◽  
Human Carcinoma Cell

Curcuma purpurascensBl., belonging to the Zingiberaceae family, is known astemu tisin Yogyakarta, Indonesia. In this study, the hydrodistilled dried ground rhizome oil was investigated for its chemical content and antiproliferative activity against selected human carcinoma cell lines (MCF7, Ca Ski, A549, HT29, and HCT116) and a normal human lung fibroblast cell line (MRC5). Results from GC-MS and GC-FID analysis of the rhizome oil oftemu tisshowed turmerone as the major component, followed by germacrone,ar-turmerone, germacrene-B, and curlone. The rhizome oil oftemu tisexhibited strong cytotoxicity against HT29 cells (IC50value of 4.9 ± 0.4 μg/mL), weak cytotoxicity against A549, Ca Ski, and HCT116 cells (with IC50values of 46.3 ± 0.7, 32.5 ± 1.1, and 35.0 ± 0.3 μg/mL, resp.), and no inhibitory effect against MCF7 cells. It exhibited mild cytotoxicity against a noncancerous human lung fibroblast cell line (MRC5), with an IC50value of 25.2 ± 2.7 μg/mL. This is the first report on the chemical composition of this rhizome’s oil and its selective antiproliferative effect on HT29. The obtained data provided a basis for further investigation of the mode of cell death.

Sacasg and sacalg: new GFP-labelled camel skin and lung fibroblast cell lines

2016 ◽  
Vol 23 (1) ◽  
pp. 73 ◽  
Author(s):  
Abdullah Alawad ◽  
Othman Alhazzaa ◽  
Mohammad Alkhrayef ◽  
Faisal Alagrafi ◽  
Ziyad Alhamdan ◽  
...  
Keyword(s):  
Cell Lines ◽  
Fibroblast Cell ◽  
Lung Fibroblast ◽  
Fibroblast Cell Lines
Sign in / Sign up

Export Citation Format

Share Document