Comparative study of platelet activation markers in diabetes mellitus patients complicated by cerebrovascular disease

2001 ◽  
Vol 12 (7) ◽  
pp. 531-537 ◽  
Author(s):  
Z. Y. Wang ◽  
J. M. Shi ◽  
Y. Han ◽  
Y. C. Wang ◽  
C. G. Ruan
Keyword(s):  
Diabetes Mellitus ◽  
Comparative Study ◽  
Cerebrovascular Disease ◽  
Platelet Activation ◽  
Activation Markers

Clinical Application of Detecting Platelet Activation Markers in Cerebrovascular Disease

2000 ◽  
Vol 27 (5) ◽  
pp. 250-255
Author(s):  
J.A. Zeller ◽  
P. Zunker ◽  
A. Lenz ◽  
D. Tschöpe ◽  
C. Kessler ◽  
...  
Keyword(s):  
Cerebrovascular Disease ◽  
Clinical Application ◽  
Platelet Activation ◽  
Activation Markers

Influence of Metabolic Control on Thromboxane Biosynthesis and Plasma Plasminogen Activator Inhibitor Type-1 in Non-insulin-dependent Diabetes mellitus

1996 ◽  
Vol 76 (01) ◽  
pp. 034-037 ◽  
Author(s):  
Giovanni Davì ◽  
Mario Belvedere ◽  
Sergio Vingneri ◽  
Isabella Catalano ◽  
Carlo Giammarresi ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Metabolic Control ◽  
Platelet Activation ◽  
Macrovascular Disease ◽  
Dependent Diabetes Mellitus ◽  
Secondary Failure ◽  
Diet And Exercise ◽  
Strict Diet ◽  
Niddm Patients ◽  
Pai 1

SummaryWe have previously shown that tight metabolic control by insulin therapy reduced thromboxane-dependent platelet activation in noninsulin-dependent diabetes mellitus (NIDDM) patients. The present study was undertaken to determine whether a similar effect could be obtained without switching diabetics in secondary failure to insulin treatment. For this purpose, we gave strict diet and exercise advise program and adjusted on a weekly basis the oral antidiabetic therapy (glipizide) that 26 patients with NIDDM had been given over the previous months.Basal measurements of urinary ll-dehydro-TXB2 and PAI-1 confirmed previous findings of enhanced levels of these parameters in NIDDM patients with macrovascular disease in comparison to age-and sex-matched controls. After 2-6 weeks, 16 patients achieved tight metabolic control associated with significant reduction of both thromboxane biosynthesis and PAI-1 levels; 10 patients remained in poor control and no significant decrease of both parameters was observed.We conclude that reduction of in-vivo platelet activation and PAI-1 antigen levels after metabolic improvement obtained by frequent reassessment of sulphonylurea therapy together with strict diet and exercise programs may have beneficial effects on the progression of diabetic micro- and macrovascular disease.

Dipeptidyl peptidase‐4 inhibitor‐related bullous pemphigoid: A comparative study of 100 patients with bullous pemphigoid and diabetes mellitus

2021 ◽  
Vol 48 (4) ◽  
pp. 486-496 ◽  
Author(s):  
Kumutnart Chanprapaph ◽  
Nathathai Pratumchart ◽  
Preeyachat Limtong ◽  
Suthinee Rutnin ◽  
Chonlaphat Sukasem ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Comparative Study ◽  
Bullous Pemphigoid ◽  
Dipeptidyl Peptidase ◽  
Dipeptidyl Peptidase 4 ◽  
Dipeptidyl Peptidase 4 Inhibitor

Changes in Coagulation and Platelet Activation Markers Following Transcatheter Left Atrial Appendage Closure

2017 ◽  
Vol 120 (1) ◽  
pp. 87-91 ◽  
Author(s):  
Josep Rodés-Cabau ◽  
Gilles O'Hara ◽  
Jean-Michel Paradis ◽  
Mathieu Bernier ◽  
Tania Rodriguez-Gabella ◽  
...  
Keyword(s):  
Platelet Activation ◽  
Left Atrial ◽  
Left Atrial Appendage ◽  
Atrial Appendage ◽  
Left Atrial Appendage Closure ◽  
Activation Markers
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