Haptoglobin polymorphism and complications in established essential arterial hypertension

1993 ◽  
Vol 11 (8) ◽  
pp. 861-867 ◽  
Author(s):  
Joris R. Delanghe ◽  
Daniel A. Duprez ◽  
Marc L. De Buyzere ◽  
Bernard M. Bergez ◽  
Benedikt Y. Callens ◽  
...  
Keyword(s):  
Arterial Hypertension ◽  
Essential Arterial Hypertension ◽  
Haptoglobin Polymorphism

THE α2А-ADRENORECEPTOR GENE AND PERSONALITY CHARACTERISTICS IN ADOLESCENTS WITH ESSENTIAL ARTERIAL HYPERTENSION

2017 ◽  
Vol 96 (3) ◽  
pp. 34-39 ◽  
Author(s):  
A. S. Kosovtseva ◽  
◽  
L. I. Kolesnikova ◽  
L. V. Rychkova ◽  
V. M. Polyakov ◽  
...  
Keyword(s):  
Arterial Hypertension ◽  
Personality Characteristics ◽  
Essential Arterial Hypertension

scholarly journals Salt and Sugar: Two Enemies of Healthy Blood Pressure in Children

Nutrients ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 697
Author(s):  
Simonetta Genovesi ◽  
Marco Giussani ◽  
Antonina Orlando ◽  
Francesca Orgiu ◽  
Gianfranco Parati
Keyword(s):  
Arterial Hypertension ◽  
Dietary Intake ◽  
Children And Adolescents ◽  
Eating Habits ◽  
Clinical Problem ◽  
Sweet Taste ◽  
Pediatric Age ◽  
Wide Availability ◽  
Essential Arterial Hypertension ◽  
Hypertension In Children

The prevalence of essential arterial hypertension in children and adolescents has grown considerably in the last few decades, making this disease a major clinical problem in the pediatric age. The pathogenesis of arterial hypertension is multifactorial, with one of the components being represented by incorrect eating habits. In particular, excessive salt and sugar intake can contribute to the onset of hypertension in children, particularly in subjects with excess weight. Babies have an innate predisposition for sweet taste, while that for salty taste manifests after a few weeks. The recent modification of dietary styles and the current very wide availability of salt and sugar has led to an exponential increase in the consumption of these two nutrients. The dietary intake of salt and sugar in children is in fact much higher than that recommended by health agencies. The purpose of this review is to explore the mechanisms via which an excessive dietary intake of salt and sugar can contribute to the onset of arterial hypertension in children and to show the most important clinical studies that demonstrate the association between these two nutrients and arterial hypertension in pediatric age. Correct eating habits are essential for the prevention and nondrug treatment of essential hypertension in children and adolescents.

PREVALENCE OF ESSENTIAL ARTERIAL HYPERTENSION IN CHILDREN AND ADOLESCENTS OF DAGESTAN AND THE CONTENT OF Mg, K, Ca, Zn, Pb IN SOILS AND NATURAL WATERS OF THE TERRITORY

2021 ◽  
Vol 100 (5) ◽  
pp. 203-208
Author(s):  
Sh.K. Salikhov ◽  
◽  
D.Z. Alieva ◽  
U.A. Magomedova ◽  
S.О. Abdulkadyrova ◽  
...  
Keyword(s):  
Arterial Hypertension ◽  
Natural Waters ◽  
Chemical Elements ◽  
The Body ◽  
Cross Sectional ◽  
Number Of Patients ◽  
Significant Difference ◽  
Geochemical Factors ◽  
Essential Arterial Hypertension ◽  
The Republic

The aim of the study is to determine the role of geochemical factors (the content of Mg, K, Ca, Zn, Pb in soils and natural waters of the plain zone of Dagestan) in the prevalence of essential arterial hypertension (EAH) among the population of children. Materials and methods of research: an observational cross-sectional (one-step) study of the prevalence of EAH in the child population was carried out. The prevalence rates of EAH among children in the plain zone of the Republic of Dagestan are calculated for 100,000 children 0–17 years old, without taking into account gender differences. The content of elements (Mg, K, Ca, Zn, Pb) in the environment (soil, natural waters) was determined by atomic absorption spectroscopy. Results: one-way analysis of variance (One-Way ANOVA) of indicators of the content of metals (Mg, K, Ca, Zn, Pb) in the regions and objects (soils, natural waters) of the study revealed a statistically significant difference in the data (for soils: F=81,06772, p<0,0002; for natural waters: F=58,86451, p<0,00001). The dependence of children's EAH on the content of chemical elements in the objects of the biosphere of Dagestan was determined, which was expressed in an increase in the number of patients with EAH when Pb content exceeded (r=+ 0,576, r=+ 0,759) and with the decrease of Mg (r=–0,668, r=–0,173), K (r=–0,440, r=–0,636), Ca (r=–0,693, r=–0,533), Zn (r=–0,051, r=–0,827) in soils and natural waters. Conclusion: when assessing the pathogenesis of EAH in the population of children, the content of Mg, K, Ca, Zn, Pb in soil and water should be taken into account, since these microelements, entering the body with water and food, affect the elemental status of child's body.

Leptinemia, parameters of heart rate variability, and prognosis in patients with essential arterial hypertension with obesity

2014 ◽  
Vol 18 (4 (72)) ◽  
Author(s):  
O. Radchenko ◽  
N. Bek ◽  
V. Potapov
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Essential Hypertension ◽  
Arterial Hypertension ◽  
Cardiovascular Events ◽  
Serum Leptin ◽  
Ventricular Systole ◽  
Essential Arterial Hypertension

An examination of 103 patients with essential hypertension and obesity showed the dependence of autonomic cardioregulation, electrical ventricular systole, and prediction of adverse cardiovascular events on the serum leptin concentration (hyper-, normo – or hypoleptinemia).

Essential arterial hypertension patients present higher cell adhesion forces, contributing to fibrinogen-dependent cardiovascular risk

Nanoscale ◽  
2017 ◽  
Vol 9 (39) ◽  
pp. 14897-14906 ◽  
Author(s):  
Ana F. Guedes ◽  
Filomena A. Carvalho ◽  
Carlos Moreira ◽  
José B. Nogueira ◽  
Nuno C. Santos
Keyword(s):  
Cell Adhesion ◽  
Cardiovascular Risk ◽  
Arterial Hypertension ◽  
Adhesion Forces ◽  
Essential Arterial Hypertension

Arterial hypertension patients present stronger erythrocyte–erythrocyte interactions and high levels of γ′ fibrinogen, which compromise microcirculation and increase the cardiovascular risk.

scholarly journals Essential arterial hypertension and polymorphism of angiotensiongen M235T gene

2002 ◽  
Vol 6 (2) ◽  
pp. 245-250 ◽  
Author(s):  
Lucia Procopciuc ◽  
T. Popescu ◽  
Gh. Jebeleanu ◽  
D. Pop ◽  
D. Zdrengehea
Keyword(s):  
Arterial Hypertension ◽  
Essential Arterial Hypertension

scholarly journals Effects of Uric Acid Lowering Therapy in Patients With Essential Arterial Hypertension

2021 ◽  
Author(s):  
Krystian Gruszka ◽  
Tomasz Drożdż ◽  
Wiktoria Wojciechowska ◽  
Piotr Jankowski ◽  
Michał Terlecki ◽  
...  
Keyword(s):  
Uric Acid ◽  
Arterial Hypertension ◽  
Elevated Serum ◽  
Intima Media Thickness ◽  
Volume Index ◽  
Control Group ◽  
Lowering Therapy ◽  
Essential Arterial Hypertension ◽  
Hs Crp

Abstract Background Asymptomatic hyperuricemia (AHU) is defined as elevated serum uric acid (UA) concentration without symptoms. This study aimed to determine the effects of AHU treatment with allopurinol on selected hypertension mediated organ damage (HMOD) indices in patients with uncomplicated essential arterial hypertension (AH). MethodsPatients aged 30-70 years with AHU and essential hypertension grade 1-2 with adequate blood pressure (BP) control, without previous urate lowering therapy (ULT) were divided into two groups: a) receiving allopurinol (ULT group) and b) age-and sex matched patients without ULT (control group). Both groups received UA-lowering diet. BP (office, 24 hour and central), echocardiographic parameters, pulse-wave velocity, carotid intima-media thickness (IMT) and lab tests (high-sensitivity C-reactive protein (hs-CRP) were measured at baseline and at 6 months follow-up.ResultsOut of 100 participants 87 completed the study (44 ULT patients and 43 controls). At 6 months follow-up, there was a significantly greater reduction in serum UA concentration in the ULT group than in the control group (464±68.8 µmol/l vs 314±55.6 µmol/l, p<0.0001). Patients receiving allopurinol had significant reductions in office systolic (137±11.8 mmHg vs 134±9.3 mmHg; p=0.025) and diastolic BP (83±9.9 mmHg vs 79±8.7 mmHg, p=0.017), central systolic BP (56±8.9 mmHg vs 51±12.9 mmHg, p=0.046), pulse pressure (43±10.4 mmHg vs 39±11.2 mmHg, p=0.017), IMT (0.773±0.121 mm vs 0.752±0.13 mm, p=0.044), left atrium volume index (40±13.5 ml/m2 vs 38±12.3 ml/m2, p=0.044), and hs-CRP level (3.36±2.73 mg/l vs 2.74±1.91 mg/l, p=0.028) compared to controls. The decrease in UA concentration was significantly related to the reduction in IMT (R=0.37, p<0.001), central SBP (R=0.26, p=0.015) and hs-CRP concentration (R=0.30, p=0.004). Multivariate regression analysis revealed the independent relationship between reduction in IMT and UA lowering (R=0.3234, R2=0.0722, p<0.026).ConclusionsIn patients with AH and asymptomatic hyperuricemia treatment with allopurinol leads to further improvement in BP control and reduction in HMOD intensity, in particular IMT. The decrease in hs-CRP concentration associated with ULT may have a beneficial effect on patient long-term prognosis.

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