FRAGILITY OF BONES IN CHRONIC DISEASE OF THE CENTRAL NERVOUS SYSTEM

Schistosomiasis is a parasitic trematode infection. Depending on the species of fluke, gastrointestinal or genitourinary tract disease develops with occasional involvement of other organs including the central nervous system. The great burden of chronic disease is in endemic countries but travellers can become infected through exposure to contaminated water in lakes and rivers. An acute symptomatic infection is sometimes seen and needs to be considered in the appropriate clinical context in travellers returning from the tropics.

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Proceedings of the Sleep and Epilepsy Workgroup: Section 2 Comorbidities: Sleep Related Comorbidities of Epilepsy

Epilepsy Currents ◽

10.1177/15357597211004549 ◽

2021 ◽

pp. 153575972110045

Author(s):

Milena K. Pavlova ◽

Marcus Ng ◽

Rebecca M. Allen ◽

Melanie Boly ◽

Sanjeev Kothare ◽

...

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Chronic Disease ◽

Circadian Rhythms ◽

Sleep Disorders ◽

Treatment Options ◽

Interdisciplinary Approach ◽

Sleep Medicine ◽

The Central Nervous System ◽

Treatment Priorities

Epilepsy is a chronic disease with multiple, complex comorbidities. Bidirectional relationships exist among seizures, sleep, circadian rhythms, and diseases within and outside of the central nervous system. Seizures fragment sleep and can contribute to development of sleep disorders, which in turn leads to worse overall health and more seizures. Moreover, treatment options are often limited by interactions with anti-seizure medications. Advances in the fields of epilepsy and in sleep medicine have been made separately, and therefore treating patients with these comorbidities necessitates interdisciplinary approach. The focus of this section of the Sleep and Epilepsy Workgroup was to identify methods of collaboration and outline investigational, educational, and treatment priorities to mutually advance what we consider a combined field.

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Some modern methods of diagnosis and pathogenetic therapy of multiple sclerosis

Neurology Bulletin ◽

10.17816/nb87566 ◽

2002 ◽

Vol XXXIV (1-2) ◽

pp. 65-72

Author(s):

I. D. Stolyarov ◽

G. N. Bisaga ◽

M. V. Votintseva ◽

A. G. Ilves ◽

I. G. Nikiforova ◽

...

Keyword(s):

Multiple Sclerosis ◽

Central Nervous System ◽

Nervous System ◽

Chronic Disease ◽

Young People ◽

Neurological Disease ◽

Genetically Engineered ◽

Modern Methods ◽

Pathogenetic Therapy ◽

The Central Nervous System

Multiple sclerosis (MS) is a severe chronic disease of the central nervous system (CNS) that affects young people and quickly leads to disability. Until now, the pathogenesis of this neurological disease, which is the most expensive for society, has not been fully elucidated, and the drugs used to treat MS patients can only slightly suspend but not interrupt the development of the disease. At the same time, the possibilities of diagnosing and treating MS have expanded due to the active study and implementation of neuroimaging, neuroimmunological and neurophysiological methods, and the use of new immunocorrecting genetically engineered drugs.

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Multiple Sclerosis

10.1093/oxfordhb/9780199797004.013.020 ◽

2013 ◽

Author(s):

Laura M. Hancock ◽

Jared M. Bruce ◽

Sharon G. Lynch

Keyword(s):

Multiple Sclerosis ◽

Central Nervous System ◽

Nervous System ◽

Chronic Disease ◽

Major Depression ◽

Cognitive Deficits ◽

Neurological Symptoms ◽

Screening Tools ◽

The Central Nervous System

Multiple sclerosis (MS) is a chronic disease that affects the central nervous system and can cause a wide variety of both physical and cognitive deficits. Mood disturbances are common, with as many as 50% of patients receiving a diagnosis of major depression during their lifetime. The risk of suicide is high and leaving depression untreated is associated with a host of additional MS symptoms. Depression in MS presents clinicians with unique challenges, as it is often difficult to distinguish from common neurological symptoms. The authors discuss recommended screening tools and therapeutic methods that can assist the clinician in successfully identifying and treating depression in MS.

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Paced auditory serial addition test (PASAT): a very difficult test even for individuals with high intellectual capability

Arquivos de Neuro-Psiquiatria ◽

10.1590/s0004-282x2011000400014 ◽

2011 ◽

Vol 69 (3) ◽

pp. 482-484 ◽

Cited By ~ 15

Author(s):

Joseph Bruno Bidin Brooks ◽

Vinicius Oliveira Giraud ◽

Youssef Jamal Saleh ◽

Samuel Jose Rodrigues ◽

Lucas Afonso Daia ◽

...

Keyword(s):

Multiple Sclerosis ◽

Central Nervous System ◽

Nervous System ◽

Chronic Disease ◽

Cognitive Function ◽

Cognitive Testing ◽

The Central Nervous System ◽

Serial Addition ◽

Intellectual Level

OBJECTIVE: To assess the difficulty of paced auditory serial addition test (PASAT) in a population of high intellectual level, under ideal cognitive testing circumstances. METHOD: One hundred medical students underwent PASAT testing. They had slept well the night before, they had eaten before the assessment, they were not using any drugs that could affect the central nervous system and they did not have depression, anxiety or any chronic disease. RESULTS: The average result from the three-second version of PASAT was 57.5% and, from the two-second version, it was 44.3%. CONCLUSION: Even under ideal circumstances, PASAT is a very difficult test for the general population. It may not be ideal for neurologists to screen, assess and follow up patients with cognitive function in multiple sclerosis.

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Decision letter for "Differential expression of five prosomatostatin genes in the central nervous system of the catshark Scyliorhinus canicula"

10.1002/cne.24898/v1/decision1 ◽

2019 ◽

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Differential Expression ◽

Scyliorhinus Canicula ◽

The Central Nervous System

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Review for "The central nervous system of whip spiders (Amblypygi): large mushroom bodies receive olfactory and visual input"

10.1002/cne.25045/v1/review1 ◽

2020 ◽

Author(s):

Harald Wolf

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Visual Input ◽

Mushroom Bodies ◽

The Central Nervous System

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Effects of Hyperoxia on Lung Utrastructure

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100067121 ◽

1970 ◽

Vol 28 ◽

pp. 26-27

Author(s):

Gladys Harrison

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Light Microscopy ◽

Oxygen Effects ◽

Age Dependent ◽

The Central Nervous System ◽

The Subject ◽

Space Age ◽

Alveolar Septa ◽

Extensive Damage

With the advent of the space age and the need to determine the requirements for a space cabin atmosphere, oxygen effects came into increased importance, even though these effects have been the subject of continuous research for many years. In fact, Priestly initiated oxygen research when in 1775 he published his results of isolating oxygen and described the effects of breathing it on himself and two mice, the only creatures to have had the “privilege” of breathing this “pure air”.Early studies had demonstrated the central nervous system effects at pressures above one atmosphere. Light microscopy revealed extensive damage to the lungs at one atmosphere. These changes which included perivascular and peribronchial edema, focal hemorrhage, rupture of the alveolar septa, and widespread edema, resulted in death of the animal in less than one week. The severity of the symptoms differed between species and was age dependent, with young animals being more resistant.

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