INDEX OF PAIRED HELICAL FILAMENT PATHOLOGY IN THE TEMPORALLOBE; RELATION TO BRAAK STAGE AND COGNTITVE FUNCTION IN THE RELIGIOUS STUDY

1997 ◽  
Vol 56 (5) ◽  
pp. 615 ◽  
Author(s):  
E J Cochran ◽  
D A Bennett ◽  
L A Beckett ◽  
M Nainys ◽  
E J Mufson
Keyword(s):  
Religious Study ◽  
Braak Stage ◽  
Paired Helical Filament

Strategizing the Sacred

2017 ◽  
Author(s):  
Avi Max Spiegel
Keyword(s):  
Political Party ◽  
Religious Study ◽  
Religious Authority ◽  
New Ideas ◽  
Party Members ◽  
A Site

This chapter suggests that the representations of religion in young Islamists' lives are not the product of prevarication, but rather of personalization. Religious authority has become circulated to such an extent that it has come to mean multiple things to multiple members. In the midst of this diversification, political party members increasingly appropriate the authority to interpret and represent what “Islam” means or should mean to others. None of these myriad representations constitutes “lies.” Instead, these words and constructions represent and reflect members' own strategic desires for themselves. The chapter shows how the haraka represents for some a site for religious study, a place of Qurʾanic learning unfettered by politics. For others, it is a place to make contacts and to get ahead: an instrumental, not ideological, site. For still others, it serves as a strategic site, a place to try out new ideas, and even as a convenient scapegoat. And, yet, for others, it is completely ignored; it simply has no place in their lives as party members.

Black Muslimness Mobilized

2019 ◽  
Vol 36 (1) ◽  
Author(s):  
Youssef J. Carter
Keyword(s):  
United States ◽  
South Carolina ◽  
Religious Study ◽  
The United States ◽  
Black Atlantic ◽  
West African ◽  
Religious Leader ◽  
American Muslims ◽  
The Rich ◽  
Sufi Order

The Mustafawi Tariqa is a transnational Sufi Order that was initiated in 1966 by the late Cheikh Mustafa Gueye Haydara (d. 1989) in Thiès, Senegal. Yet, only since 1994 has this specific Sufi network reached westward across the water, bringing American Muslims—many of whom are converts—into the larger network. In the United States, the majority of students who have entered the Tariqa and have declared allegiance (bayah) to Shaykh Arona Rashid Faye Al-Faqir are African-Americans who have inserted themselves religiously, culturally, and pedagogically into a West African Sufi tradition which emphasizes religious study and the practice of dhikr (remembrance of God). Shaykh Arona Faye is a Senegalese religious leader who relocated to the southeastern region of the United States from West Africa to spread the religion of Islam and expose American Muslims to the rich West African tradition of spiritual purification and Islamic piety. At the same time, many of those who are African-American members of this tradition have made it a point to travel to Senegal themselves to strengthen transatlantic ties with West African compatriots and visit sacred burial sites in the small city of Thiès. I examine how two sites of pilgrimage for the Mustafawi—Moncks Corner, South Carolina and Thiès, Senegal—play a part in the infrastructure of Black Atlantic Sufi network. Moncks Corner is the central site in which access to the Tariqa’s most charismatic living shaykh, Shaykh Arona Faye, has worked for the past two decades teaching and mentoring those on the Path. On the other hand, Thiès is the location where the Tariqa’s founder is buried and travelers visit the town in order to pay homage to his memory. I show how these sites catalyze mobility and operate as spaces of spiritual refuge for visitors in both local and regional contexts by looking at how a local zawiyah produces movement in relation to a broader tariqa. By looking at pilgrimage and knowledge transmission, I argue that the manner in which esoteric approaches to spiritual care and the embodiment of higher Islamic ethics via the West African Sufi methodology of the Mustafawi informs the manner in which Muslims of varying African descent inhabit a broader diasporic identification of “Black Muslimness.”

A MASONIC ARTIFACT IN OREL: THE FEATURES OF ONE RELIGIOUS STUDY

2020 ◽  
Vol 9 (3) ◽  
pp. 101-110
Author(s):  
Yu.A. KOROLEV ◽  
Keyword(s):  
United States ◽  
Cultural Study ◽  
Religious Study ◽  
The United States ◽  
History Of

The purpose of the article is to present the results of a preliminary religious and historical-cultural study of the band with Masonic symbols from the collection of famous Orel collector P. Based on the analysis of the Masonic symbols placed on the band, the author defines this artifact as part of the ritual vestment of a Mason of the 33-rd degree of dedication of the Scottish Charter of the Southern Jurisdiction of the United States and establishes its approximate dating. After a brief review of the history of this Masonic organization a hypothesis is put forward that this item belongs to specific individuals from among the leaders of the Scottish Charter of the United States. At the same time the author draws attention to cultural-historical and collectible value of this artifact and points out the desirability of conducting a comprehensive scientific examination.

Children

2018 ◽  
Author(s):  
Donald R. Davis
Keyword(s):  
Religious Study ◽  
Legal Capacity ◽  
Religious Training

Classical Hindu law distinguishes the childhood, youth, and adulthood of male children in terms of ritual and legal eligibility and duty. Childhood is marked both by freedom from the constraints and obligations of ritual and law and by ritual ineligibility and legal incapacity. The consecratory rite of the sacred thread marks a son’s eligibility and obligation for religious study and ritual. Youth is the period of religious training that culminates in the completion of studies and in marriage. Legal majority is recognized for sons at age sixteen, while full ritual rights and duties commence only with marriage. In the classical texts, the onset of menstruation marks a daughter’s eligibility to marry, though her legal capacity remains restricted in principle. Daughters thus figure prominently in the intricate negotiations of marriage, kinship, and family reputation.

scholarly journals Mitochondrial complex I abnormalities is associated with tau and clinical symptoms in mild Alzheimer’s disease

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Tatsuhiro Terada ◽  
Joseph Therriault ◽  
Min Su Peter Kang ◽  
Melissa Savard ◽  
Tharick Ali Pascoal ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Mitochondrial Dysfunction ◽  
Complex I ◽  
Clinical Symptoms ◽  
Mitochondrial Complex I ◽  
Braak Stage ◽  
Mitochondrial Complex ◽  
Temporal Area

Abstract Background Mitochondrial electron transport chain abnormalities have been reported in postmortem pathological specimens of Alzheimer’s disease (AD). However, it remains unclear how amyloid and tau are associated with mitochondrial dysfunction in vivo. The purpose of this study is to assess the local relationships between mitochondrial dysfunction and AD pathophysiology in mild AD using the novel mitochondrial complex I PET imaging agent [18F]BCPP-EF. Methods Thirty-two amyloid and tau positive mild stage AD dementia patients (mean age ± SD: 71.1 ± 8.3 years) underwent a series of PET measurements with [18F]BCPP-EF mitochondrial function, [11C]PBB3 for tau deposition, and [11C] PiB for amyloid deposition. Age-matched normal control subjects were also recruited. Inter and intrasubject comparisons of levels of mitochondrial complex I activity, amyloid and tau deposition were performed. Results The [18F]BCPP-EF uptake was significantly lower in the medial temporal area, highlighting the importance of the mitochondrial involvement in AD pathology. [11C]PBB3 uptake was greater in the temporo-parietal regions in AD. Region of interest analysis in the Braak stage I-II region showed significant negative correlation between [18F]BCPP-EF SUVR and [11C]PBB3 BPND (R = 0.2679, p = 0.04), but not [11C] PiB SUVR. Conclusions Our results indicated that mitochondrial complex I is closely associated with tau load evaluated by [11C]PBB3, which might suffer in the presence of its off-target binding. The absence of association between mitochondrial complex I dysfunction with amyloid load suggests that mitochondrial dysfunction in the trans-entorhinal and entorhinal region is a reflection of neuronal injury occurring in the brain of mild AD.

Alzheimer’s Disease-Related Neuropathology Among Patients with Medication Treated Type 2 Diabetes in a Community-Based Autopsy Cohort

2021 ◽  
pp. 1-10
Author(s):  
Douglas Barthold ◽  
Laura E. Gibbons ◽  
Zachary A. Marcum ◽  
Shelly L. Gray ◽  
C. Dirk Keene ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Sex Education ◽  
Descriptive Analysis ◽  
Neurofibrillary Tangle ◽  
Apoe Genotype ◽  
Severity Index ◽  
Neuritic Plaque ◽  
Braak Stage ◽  
Total N

Background: Diabetes is a risk factor for Alzheimer’s disease and related dementias (ADRD). Epidemiologic evidence shows an association between diabetes medications and ADRD risk; cell and mouse models show diabetes medication association with AD-related neuropathologic change (ADNC). Objective: This hypothesis-generating analysis aimed to describe autopsy-measured ADNC for individuals who used diabetes medications. Methods: Descriptive analysis of ADNC for Adult Changes in Thought (ACT) Study autopsy cohort who used diabetes medications, including sulfonylureas, insulin, and biguanides; total N = 118. ADNC included amyloid plaque distribution (Thal phasing), neurofibrillary tangle (NFT) distribution (Braak stage), and cortical neuritic plaque density (CERAD score). We also examined quantitative measures of ADNC using the means of standardized Histelide measures of cortical PHF-tau and Aβ 1–42. Adjusted analyses control for age at death, sex, education, APOE genotype, and diabetes complication severity index. Results: Adjusted analyses showed no significant association between any drug class and traditional neuropathologic measures compared to nonusers of that class. In adjusted Histelide analyses, any insulin use was associated with lower mean levels of Aβ 1–42 (–0.57 (CI: –1.12, –0.02)) compared to nonusers. Five years of sulfonylureas and of biguanides use was associated with lower levels of Aβ 1–42 compared to nonusers (–0.15 (CI: –0.28, –0.02), –0.31 (CI: –0.54, –0.07), respectively). Conclusion: Some evidence exists that diabetes medications are associated with lower levels of Aβ 1–42, but not traditional measures of neuropathology. Future studies are needed in larger samples to build understanding of the mechanisms between diabetes, its medications, and ADRD, and to potentially repurpose existing medications for prevention or delay of ADRD.

Sign in / Sign up

Export Citation Format

Share Document