Association of Ureaplasma Urealyticum in the Placenta with Perinatal Morbidity and Mortality

Preeclampsia is a serious complication of pregnancy and complicates its course in 2-8% of all cases. According to the literature, the disease is associated with an increase in maternal and perinatal morbidity and mortality, and is a predictor of the development of chronic diseases in the distant future, which is an important medical and social issue. Of particular interest is the study of the molecular mechanisms of etiopathogenesis and risk factors for preeclampsia, which, unfortunately, are currently poorly studied and understood, thus dictating the need for further study of this complication of pregnancy. This article discusses the current understanding of the etiology, pathogenesis and risk factors for preeclampsia.

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Editorial–Special Issue

Twin Research and Human Genetics ◽

10.1017/thg.2016.30 ◽

2016 ◽

Vol 19 (3) ◽

pp. 167-167 ◽

Cited By ~ 2

Author(s):

Mark P. Umstad ◽

Ricardo Palma-Dias ◽

Asma Khalil

Keyword(s):

Well Being ◽

Morbidity And Mortality ◽

Perinatal Morbidity ◽

Special Issue ◽

Monochorionic Twin ◽

Editorial Special Issue ◽

Twin Pregnancies

Monochorionic twin pregnancies are subject to unique complications that can threaten the life and well-being of both fetuses, resulting in a disproportionate increase in perinatal morbidity and mortality.

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Maternal and fetal outcome in oligohydramnios after 34 weeks of gestation

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20184515 ◽

2018 ◽

Vol 7 (11) ◽

pp. 4604

Author(s):

Mahantappa A. Chiniwar ◽

Joe Kaushik M. ◽

Sharada B. Menasinkai

Keyword(s):

Amniotic Fluid ◽

Fetal Outcome ◽

Morbidity And Mortality ◽

Research Centre ◽

Control Group ◽

P Value ◽

Study Group ◽

Perinatal Morbidity ◽

Amniotic Fluid Index ◽

Chi Square

Background: Oligohydramnios is one of the major causes of maternal and perinatal morbidity and mortality. It is a clinical condition characterized by Amniotic Fluid Index (AFI) ≤5 cm by sonographic assessment. The aim of present study is to know the maternal and fetal outcome in oligohydramnios after 34 weeks of gestation compared with women who had normal volume of amniotic fluid.Methods: Study was done for the period of 21 months from November 2014-July 2016 at Adichunchanagiri Institute of Medical Sciences, Hospital and Research Centre Bellur. 50 antenatal cases with > 34 weeks of gestation with AFI ≤5 cm by ultrasonographic estimation were included as study group and 50 women with normal AFI were included as control group. Maternal and fetal outcome of the women with oligohydramnios were analyzed and compared with control group.Results: Results were analyzed statistically using parameters like mean, SD, Chi Sq test, P value. Amniotic fluid was clear in 32% in study and 78% in control group, thin meconium stained in 30% in study group and 14%in control group and was thick meconium stained in 38% in study group and 8% in control group (Chi square =22.31, p<0.0001). Induction of labour was done in 54% in study group and 20% in control group. Cesarean delivery was done in 58% in study group women and 28% in control group women. Regarding the birth weight of babies 62% were < 2.5 kg in study group and 18% in control group with p<0.001. 10% of babies in study group required NICU admission and perinatal mortality was 2%.Conclusions: Due to increased perinatal morbidity and mortality and increased rate of LSCS, timely decision during labour is important to reduce perinatal morbidity and mortality.

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Perinatal Morbidity and Mortality in the Regional University Teaching Hospital of Borgou (BENIN) In 2013

Clinics in Mother and Child Health ◽

10.4172/2090-7214.1000244 ◽

2016 ◽

Vol 13 (2) ◽

Author(s):

d Almeida M ◽

Noudamadjo A

Keyword(s):

Teaching Hospital ◽

Morbidity And Mortality ◽

University Teaching ◽

Perinatal Morbidity ◽

Regional University

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Influence of the Human Development Index on the Maternal–Perinatal Morbidity and Mortality of Pregnant Women with SARS-CoV-2 Infection: Importance for Personalized Medical Care

Journal of Clinical Medicine ◽

10.3390/jcm10163631 ◽

2021 ◽

Vol 10 (16) ◽

pp. 3631

Author(s):

Yolanda Cuñarro-López ◽

Santiago García-Tizón Larroca ◽

Pilar Pintado-Recarte ◽

Concepción Hernández-Martín ◽

Pilar Prats-Rodríguez ◽

...

Keyword(s):

Pregnant Women ◽

Human Development ◽

Human Development Index ◽

Maternal Morbidity ◽

Tertiary Care ◽

Country Of Origin ◽

Morbidity And Mortality ◽

Inverse Association ◽

Perinatal Morbidity ◽

Development Index

Coronavirus disease-19 (COVID-19) is perhaps the most worrisome pandemic in the 21st century, having entailed devastating consequences for the whole society during the last year. Different studies have displayed an existing association between pregnancy and COVID-19 severity due to the various physiological changes that occur during gestation. Recent data identified maternal country of origin as an important determinant of COVID-19 presentation in pregnant women. However, the explanation of this fact remains to be fully elucidated. Therefore, the purpose of this work is to analyze the possible relationship between Human Development Index (HDI) of maternal country of origin with the morbimortality of pregnant women and their newborns. Here, we conducted a multicentric, ambispective, observational case-control study (1:1 ratio) and compare with the HDI of each country (group 1—very high HDI, group 2—high HDI, group 3—medium HDI, and group 4—low HDI). In total, 1347 pregnant women with confirmed SARV-CoV-2 infection (cases) were enrolled, and each was paired with one control to give a total number of 2694 participants from 81 tertiary care centers. Among the women with SARS-CoV-2 infection, more cases were produced of perinatal mortality, overall maternal morbidity, COVID-19 maternal morbidity, C-sections, hypertensive maternal morbidity, and perinatal morbidity. Our results described an inverse association between HDI and maternofetal morbidity and mortality. Moreover, the countries with an HDI lower than 1 showed higher rates of patients with maternal COVID-19-related morbidity (6.0% vs. 2.4%, p < 0.001), a need for oxygen therapy (4.7% vs. 1.8%, p < 0.001), and maternal ICU admission (2.6% vs. 1.0%, p = 0.007). Compared to other risk factors such as overweight, obesity, preexisting and obstetric comorbidities, HDI emerged as an independent risk factor explaining much of the increased maternal–perinatal morbidity and mortality detected in our group of cases. Further research is needed to establish to confirm the real impact of this factor and its components on pregnancy outcomes.

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