scholarly journals Influence of the Human Development Index on the Maternal–Perinatal Morbidity and Mortality of Pregnant Women with SARS-CoV-2 Infection: Importance for Personalized Medical Care

2021 ◽  
Vol 10 (16) ◽  
pp. 3631
Author(s):  
Yolanda Cuñarro-López ◽  
Santiago García-Tizón Larroca ◽  
Pilar Pintado-Recarte ◽  
Concepción Hernández-Martín ◽  
Pilar Prats-Rodríguez ◽  
...  

Coronavirus disease-19 (COVID-19) is perhaps the most worrisome pandemic in the 21st century, having entailed devastating consequences for the whole society during the last year. Different studies have displayed an existing association between pregnancy and COVID-19 severity due to the various physiological changes that occur during gestation. Recent data identified maternal country of origin as an important determinant of COVID-19 presentation in pregnant women. However, the explanation of this fact remains to be fully elucidated. Therefore, the purpose of this work is to analyze the possible relationship between Human Development Index (HDI) of maternal country of origin with the morbimortality of pregnant women and their newborns. Here, we conducted a multicentric, ambispective, observational case-control study (1:1 ratio) and compare with the HDI of each country (group 1—very high HDI, group 2—high HDI, group 3—medium HDI, and group 4—low HDI). In total, 1347 pregnant women with confirmed SARV-CoV-2 infection (cases) were enrolled, and each was paired with one control to give a total number of 2694 participants from 81 tertiary care centers. Among the women with SARS-CoV-2 infection, more cases were produced of perinatal mortality, overall maternal morbidity, COVID-19 maternal morbidity, C-sections, hypertensive maternal morbidity, and perinatal morbidity. Our results described an inverse association between HDI and maternofetal morbidity and mortality. Moreover, the countries with an HDI lower than 1 showed higher rates of patients with maternal COVID-19-related morbidity (6.0% vs. 2.4%, p < 0.001), a need for oxygen therapy (4.7% vs. 1.8%, p < 0.001), and maternal ICU admission (2.6% vs. 1.0%, p = 0.007). Compared to other risk factors such as overweight, obesity, preexisting and obstetric comorbidities, HDI emerged as an independent risk factor explaining much of the increased maternal–perinatal morbidity and mortality detected in our group of cases. Further research is needed to establish to confirm the real impact of this factor and its components on pregnancy outcomes.

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Santiago García-Tizón Larroca ◽  
Francisco Amor Valera ◽  
Esther Ayuso Herrera ◽  
Ignacio Cueto Hernandez ◽  
Yolanda Cuñarro Lopez ◽  
...  

2017 ◽  
Vol 17 (1) ◽  
Author(s):  
S. Garcia-Tizon Larroca ◽  
J. Arevalo-Serrano ◽  
A. Duran Vila ◽  
M. P. Pintado Recarte ◽  
I. Cueto Hernandez ◽  
...  

2018 ◽  
Vol 73 ◽  
pp. 09018
Author(s):  
Taufiq Ahmad ◽  
Santoso Edi

The objective of the research is to analyze the success story of the Salatiga City and Semarang City in the best three achievements and position in Human Development Index in the Central Java Province 2013-2015, what kinds of policy learned can be taken. The research uses qualitative model with several informants as sources of primary data. The data is taken by interviewing with some informants, such as: Local Government Health Service of Salatiga City and Semarang City, Local Government Educational Service of Salatiga City and Semarang City, Regional body for planning and development (Bappeda) of Salatiga City and Semarang City. Triangulation method is the best way to eliminate the fact contruction differences in the context of a certain study when collecting the data about the events and relationships of the various views. Through this technique the researchers also compared the findings with a variety of sources. The study found, firstly, in the health sector, Salatiga City have mainly program, that is improve and practice OSOC (One Student One Client) program, the program focuses in pregnant women with highly risk, OSOC program involve the local government, the obsgins doctor and student of university (especially health academy student), after recoding the pregnant women with highly risk and then become the student client. Meanwhile Semarang City improves and practice EMAS (Emerging Maternal and Neonatal Survival) program based on cooperation with USAID. As we know that the maternal and neonatal mortality is important aspect of Human Development Index. Secondly: in education sector, Salatiga City and Semarang City improve and practice Local Student Operational Aid (BOSDA) and Poor Student Aid for basic and junior school student, that program can increase the educational partisipation rate.


Author(s):  
Shweta Avinash Khade ◽  
Amarjeet Kaur Bava

Background: This is an observational analytical study carried out in department of obstetrics and Gynecology, in a tertiary care center to determine the factors influencing fetal and maternal outcome, prognosis and complications in preterm premature rupture of membrane cases.Methods: The present study is a prospective observational study of perinatal and maternal outcome in 100 cases of preterm premature rupture of membranes in between 2837 weeks gestation with singleton pregnancy, from 1st March 2013 to 28th February 2014. Patients with medical complications like anemia, preexisting hypertension, diabetes, vascular or renal disease, multiple gestations, uterine or fetal anomalies etc. are excluded from the study. Detailed history, physical examinations were carried out and appropriate management instituted as per individual patients need.Results: In this study maternal morbidity was 16%. Perinatal morbidity was 33% and most common causes were hyperbilirubinemia (23%), RDS (21%).  Perinatal mortality was seen in 15% and mainly due to RDS (53%). Twenty-five (25%) neonates were delivered by cesarean. The main indications for cesarean being malpresentation (36%) followed by fetal distress (24%).Conclusions: PPROM is one of the important causes of preterm birth that can result in high perinatal morbidity and mortality along with maternal morbidity. Looking after a premature infant puts immense burden on the family, economy and health care resources of the country. An understanding of gestational age dependent neonatal morbidity and mortality is important in determining the potential benefits of conservative management of preterm PROM at any gestation.


2021 ◽  
Vol 31 (9) ◽  
pp. 1287-1291
Author(s):  
Faiza Gaba ◽  
Nicolò Bizzarri ◽  
Paul Kamfwa ◽  
Allison Saiz ◽  
Oleg Blyuss ◽  
...  

BackgroundThe Global Gynaecological Oncology Surgical Outcomes Collaborative (GO SOAR) aims to develop a network of gynecological oncology surgeons, surgical departments, and other interested parties that will have the long-term ability to collaborate on outcome studies. The protocol for the first collaborative study is presented here.Primary ObjectiveTo evaluate international variation in 30-day post-operative morbidity and mortality following gynecological oncology surgery between very high/high and medium/low human development index country settings.HypothesisThere is no variation in post-operative morbidity and mortality following gynecological oncology surgery between very high/high and medium/low human development index country settings.Study DesignInternational, multicenter, prospective cohort study. Patient data will be collected over a consecutive 30-day period through gynecological oncology multidisciplinary teams/tumor boards and clinics across different human development index country groups. All data are collected on a customized, secure, password protected, central REDCap database.Major Inclusion/Exclusion CriteriaInclusion criteria include women aged ≥18 years undergoing elective/emergency, curative/palliative surgery for primary/recurrent tubo-ovarian/peritoneal, endometrial, cervical, vulval, vaginal, gestational trophoblastic malignancies. Surgical modality may be open, minimal access (laparoscopic/robotic), or vaginal.Primary Endpoint30-day post-operative morbidity and mortality defined as per Clavien-Dindo classification system.Sample Size1100 (550/arm).Estimated Dates for Completing Accrual and Presenting ResultsIt is estimated recruitment will be completed by 2022 and results published by 2023.Trial RegistrationClinicalTrials.gov registry: NCT04579861 (https://clinicaltrials.gov/ct2/show/NCT04579861).


2003 ◽  
Vol 8 (2) ◽  
pp. 97-100 ◽  
Author(s):  
Maria José Sotelo ◽  
Luis Gimeno

The authors explore an alternative way of analyzing the relationship between human development and individualism. The method is based on the first principal component of Hofstede's individualism index in the Human Development Index rating domain. Results suggest that the general idea that greater wealth brings more individualism is only true for countries with high levels of development, while for middle or low levels of development the inverse is true.


2018 ◽  
Vol 13 (1) ◽  
Author(s):  
Adriwati Adriwati

Human development is a development paradigm that puts human (population) as the focus and final target of all development activities, namely the achievement of control over resources (income to achieve decent living), improvement of health status (long life and healthy life) and improve education. To see the success rate of human development, UNDP publishes an indicator of Human Development Index (HDI). This study discusses the achievements of human development that have been pursued by the government. The problem analyzed in this research is the difference of human development achievement in some provincial government in Indonesia. This paper aims to compare the achievements of human development in some provincial governments seen from the achievement of human development index of each province. Research location in Banten Province, West Java and DKI Jakarta.Keywords:Human Development Index, Human Development Achievement


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