Cigarette Smoking as a Risk Factor for Chronic Pancreatitis: A Case-Control Study in Japan

Pancreas ◽  
2000 ◽  
Vol 21 (2) ◽  
pp. 109-114 ◽  
Author(s):  
Yingsong Lin ◽  
Akiko Tamakoshi ◽  
Tetsuo Hayakawa ◽  
Michio Ogawa ◽  
Yoshiyuki Ohno
2015 ◽  
Vol 04 (03) ◽  
pp. 111-114 ◽  
Author(s):  
Tayeb Ghadimi ◽  
Bahman Gheitasi ◽  
Sayran Nili ◽  
Mohammad Karimi ◽  
Ebrahim Ghaderi

Abstract Purpose: The aim of this study was to investigate occupational risk factors associated with bladder cancer. Materials and Methods: In this case–control study, control group included patients who referred to a specialized clinic in the same city and hospitals where patients had been registered. Data were entered into SPSS software. Odds ratios (OR) were calculated for occupational variables and other characteristics. Then, using logistic regression, the association between cancer and drugs was studied while smoking was controlled. Results: Cigarette smoking, even after quitting, was also associated with bladder cancer (OR = 2.549). Considering the classification of occupations, the OR of working in metal industry in patients was 10.629. Multivariate analysis showed that use of the drug by itself can be a risk factor for bladder cancer. Drug abuse together with the control of smoking increased the risk of bladder cancer by 4.959. Conclusion: According to the findings of this study, contact with metal industries such as welding, and working with tin was found as a risk factor for bladder cancer. In addition, cigarette smoking and opium abuse individually were associated with bladder cancer.


2017 ◽  
Vol 15 (1) ◽  
Author(s):  
Yamin Lai ◽  
Hong Yang ◽  
Wei Han ◽  
Tao Guo ◽  
Hong Lv ◽  
...  

2021 ◽  
Author(s):  
Hiroyuki Kamao ◽  
Syunsuke Araki ◽  
Katsutoshi Goto ◽  
Kento Matsuno ◽  
Kenichi Mizukawa ◽  
...  

Abstract BackgroundCigarette smoking has been reported as a risk factor for the development of neovascular age-related macular degeneration (nAMD). However, the associations between cigarette smoking and subtypes of drusen and nAMD were incomplete, as it lacked consideration of pachydrusen or no significant drusen. Therefore, this study intended to reveal the associations between cigarette smoking and subtypes of drusen and nAMD.PurposeTo evaluate the associations between cigarette smoking and subtypes of drusen and nAMD in an Asian population.MethodsThis retrospective case-control study included 189 eyes in 189 patients with treatment-naïve nAMD, including typical AMD, polypoidal choroidal vasculopathy (PCV), and type 3 neovascularization. The patients were stratified into never-, former-, and current-smoker groups, and drusen subtypes, including no significant drusen, soft drusen, subretinal drusenoid deposits (SDDs), and pachydrusen, were analyzed in each group.ResultsThe proportions of no significant drusen and pachydrusen in the fellow eyes were significantly higher in the former- and current-smoker groups (P = 0.016 and P < 0.001), respectively. There was a significantly higher proportion of PCV in the affected eyes in the current-smoker group (P = 0.041). The proportions of SDDs in the fellow eyes and type 3 neovascularization in the affected eyes were significantly higher in the never-smoker group (P < 0.001 and P = 0.037), respectively.ConclusionEver smokers (former and current smokers) had significantly higher proportions of pachychoroid-related disorders, including no significant drusen, pachydrusen, and PCV, than nonsmokers. Thus, cigarette smoking could be a risk factor for the development of pachychoroid-dependent abnormalities.


1996 ◽  
Vol 77 (6) ◽  
pp. 570 ◽  
Author(s):  
Michael H. Levy ◽  
Maire A. Connolly ◽  
Richard J. O'Brien

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 973-973
Author(s):  
R. Gonzalez Mazario ◽  
J. J. Fragio-Gil ◽  
P. Martinez Calabuig ◽  
E. Grau García ◽  
M. De la Rubia Navarro ◽  
...  

Background:Cardiovascular disease (CV) is the most frequent cause of death in rheumatoid arthritis (RA) patients. It is well known that RA acts as an independent cardiovascular risk factor.Objectives:To assess the CV risk in RA patients using carotid ultrasonography (US) additionally to the traditional CV risk factors.Methods:A prospective transversal case control study was performed, including adult RA patients who fulfilled ACR/EULAR 2010 criteria and healthy controls matched according to CV risk factors. Population over 75 years old, patients with established CV disease and/or chronic kidney failure (from III stage) were excluded. The US evaluator was blinded to the case/control condition and evaluated the presence of plaques and the intima-media thickness. Statistical analysis was performed with R (3.6.1 version) and included a multivariate variance analysis (MANOVA) and a negative binomial regression adjusted by confounding factors (age, sex and CV risk factors).Results:A total of 200 cases and 111 healthy controls were included in the study. Demographical, clinical and US data are exposed in table 1. Not any difference was detected in terms of CV risk factors between the cases and controls. In both groups a relationship between age, BMI and high blood pressure was detected (p<0.001).Table 1.Table 2.RA basal characteristicsDisease duration (years)16,98 (11,38)Erosions (X-Ray of hands/feet)163 (81,5%)Seropositive (RF/anti-CCP)146 (73%)Extra-articular symptoms44 (22%)Intersticial difusse lung disease10 (5%)Rheumatoid nodules14 (7%)Prednisone use103 (51,5%)Median dose of Prednisone last year (mg)2,34 (2,84)sDMARDsMethotrexate104 (52%)Leflunomide29 (14,5%)Hydroxycloroquine9 (4,5%)bDMARDs89 (44,5%) TNFi41 (20,5%) Abatacept15 (7,5%) IL6i22 (11%) RTX11 (5,5%)JAKi26 (13%) Baricitinib11 (5,5%) Tofacitinib15 (7,5%)DAS 28-ESR3,1 (2,3, 3,9)SDAI7,85 (4,04, 13,41)HAQ0,88 (0,22, 1,5)RF (U/mL)51 (15, 164,25)Anti-CCP (U/mL)173 (22, 340)Patients showed higher intima-media (both right and left) thickness compared to controls (p<0.006). Moreover it was also related to the disease duration and DAS28 score (p<0.001). A higher plaque account was noted in cases(p<0.004) and it was also related to the disease duration (p<0.001).Conclusion:RA implies a higher CV risk. Traditional CV risk factors explains only partially the global risk. These findings support that RA acts as an independent cardiovascular risk factor.Disclosure of Interests:None declared


Sign in / Sign up

Export Citation Format

Share Document