A Retrospective Analysis of Adverse Events in Hyperbaric Oxygen Therapy (2012-2015)

2017 ◽  
Vol 30 (3) ◽  
pp. 125-129 ◽  
Author(s):  
Hanna Jokinen-Gordon ◽  
Richard C. Barry ◽  
Beckie Watson ◽  
D. Scott Covington
2016 ◽  
Vol 54 (1) ◽  
pp. 19-22
Author(s):  
Kinga Grobelska ◽  
Monika Betyna ◽  
Ewa Zieliński

Abstract Hyperbaric oxygen therapy (HBOT) is a safe treatment, provided fulfilling certain rules of patient qualifications to treatment, as well as supervision over the course of therapy by qualified medical staff. Side effects reported in the literature are rare, and are usually mild and transient. Professional medical staff allows minimising the adverse events occurrence. The scale of complications is unknown, especially in Polish hyperbaric center. Careful analysis could be used to develop prevention procedures for patients of hyperbaric oxygen therapy. Hyperbaric Oxygen Centre and Wound Treatment in Bydgoszcz during 28 months performed hyperbaric oxygen therapy (HBOT) in case of 423 patients. During this period, adverse events occurred occasionally. 17 cases have been reported. Authors described study case 77 year-old patient who was admitted due to non-healing wound-left lower abdomen (state after radiotherapy). During the fourth session, on decompression phase patient have had a generalized seizure (tonic-clonic). The decompression was stopped, the oxygen supply was disconnected but only after the drug administration seizures terminated. The most likely causative agent of the adverse reactions of the patient treated with HBOT was the oxygen toxic effect on the brain tissue. However, analyzing the circumstances of the seizure termination: phase of decompression at the pressure 2ATA and lack of oxygen disconnection response, it cannot be excluded other causes of this complication.


PLoS ONE ◽  
2020 ◽  
Vol 15 (6) ◽  
pp. e0234419
Author(s):  
Jasmijn D. Generaal ◽  
Corine A. Lansdorp ◽  
Onno Boonstra ◽  
Barbara L. van Leeuwen ◽  
Hubertus A. M. Vanhauten ◽  
...  

BMJ Open ◽  
2018 ◽  
Vol 8 (9) ◽  
pp. e023387 ◽  
Author(s):  
Amir Hadanny ◽  
Stefanie Abbott ◽  
Gil Suzin ◽  
Yair Bechor ◽  
Shai Efrati

ObjectivesThe aim of the study is to evaluate the effect of hyperbaric oxygen therapy (HBOT) in participants suffering from chronic neurological deficits due to traumatic brain injury (TBI) of all severities in the largest cohort evaluated so far with objective cognitive function tests and metabolic brain imaging.MethodsA retrospective analysis was conducted of 154 patients suffering from chronic neurocognitive damage due to TBI, who had undergone computerised cognitive evaluations pre-HBOT and post-HBOT treatment.ResultsThe average age was 42.7±14.6 years, and 58.4% were men. All patients had documented TBI 0.3–33 years (mean 4.6±5.8, median 2.75 years) prior to HBOT. HBOT was associated with significant improvement in all of the cognitive domains, with a mean change in global cognitive scores of 4.6±8.5 (p<0.00001). The most prominent improvements were in memory index and attention, with mean changes of 8.1±16.9 (p<0.00001) and 6.8±16.5 (p<0.0001), respectively. The most striking changes observed in brain single photon emission computed tomography images were in the anterior cingulate and the postcentral cortex, in the prefrontal areas and in the temporal areas.ConclusionsIn the largest published cohort of patients suffering from chronic deficits post-TBI of all severities, HBOT was associated with significant cognitive improvements. The clinical improvements were well correlated with increased activity in the relevant brain areas.


2013 ◽  
Vol 106 ◽  
pp. S73
Author(s):  
Y. Niwa ◽  
M. Murakami ◽  
Y. Demizu ◽  
O. Fujii ◽  
K. Terashima ◽  
...  

2018 ◽  
Vol 26 (4) ◽  
pp. 250-255 ◽  
Author(s):  
Itay Wiser ◽  
Averbuch Sagie Roni ◽  
Ella Ziv ◽  
Mony Friedman ◽  
Shay Efraty ◽  
...  

Background: Phenol chemical peeling (PCP) treatment is associated with prolonged recovery and sustained adverse events. Hyperbaric oxygen therapy (HBOT) is known to accelerate wound healing. The purpose of the current study was to evaluate the effect of HBOT on PCP recovery period and adverse events. Methods: This is a pilot randomized controlled clinical study. Women following PCP underwent 5 consecutive daily HBOT sessions, compared with PCP alone. Pain, pruritus, erythema, crusting, scaling, and edema were daily evaluated up to 28 days following PCP. Photographs taken on days 14 and 35 following PCP were assessed. Confidence to appear in public was assessed 14 days following PCP. Results: Eight participants equally assigned to HBOT and control groups. Lower severity scores for erythema, scaling, and pruritus were documented in the HBOT group (mean difference 1.19, P = .006; .84, P = .04; and 2.19, P = .001, respectively). Photographic assessment severity score was higher for skin tightness, edema, erythema, crusting, and scaling in the control group on day 14 post PCP ( P < .05) and for erythema on day 35 post PCP ( P < .05). Epithelialization percentage was higher in the HBOT group on day 14 post PCP compared with controls (98.5% ± 1% vs 94.2% ± 1%; P = .021). The HBOT group scored higher in confidence to appear in public (20.8 ± 1.7 vs 14.5 ± 1.3; P = .029). Conclusion: Hyperbaric oxygen therapy following PCP is associated with faster recovery as assessed by both patients and caregivers. So far, HBOT was mainly used in the treatment of problematic or chronic wounds. Our study suggests expanding the indications in which hyperbaric oxygen treatment is applicable and recommended.


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