scholarly journals Use of Inhaled Corticosteroids During Pregnancy and Risk of Pregnancy-Induced Hypertension: Nested Case???Control Study

2005 ◽  
Vol 60 (7) ◽  
pp. 417-418 ◽  
Author(s):  
Marie-Jos??e Martel ◽  
??velyne Rey ◽  
Marie-France Beauchesne ◽  
Sylvie Perreault ◽  
Genevi??ve Lefebvre ◽  
...  
BMJ ◽  
2005 ◽  
Vol 330 (7485) ◽  
pp. 230 ◽  
Author(s):  
Marie-Josée Martel ◽  
Évelyne Rey ◽  
Marie-France Beauchesne ◽  
Sylvie Perreault ◽  
Geneviève Lefebvre ◽  
...  

PLoS ONE ◽  
2021 ◽  
Vol 16 (5) ◽  
pp. e0250548
Author(s):  
Getachew Ossabo Babore ◽  
Tsegaye Gebre Aregago ◽  
Tadesse Lelago Ermolo ◽  
Mangistu Handiso Nunemo ◽  
Teshome Tesfaye Habebo

Background Globally, 292,982 women die due to the complications of pregnancy and childbirth per year, out of those deaths 85% occurs in Sub Saharan Africa. In Ethiopia, pre-eclampsia accounts for 11% of direct maternal deaths. Objective To determine maternal and foetal outcomes of pregnancy-induced hypertension among women who gave birth at health facilities in Hossana town administration. Methods Institutional based unmatched case-control study was conducted among women, who gave birth at health facilities from May 20 to October 30, 2018. By using Epi-Info version 7; 207 sample size was estimated, for each case two controls were selected. Two health facilities were selected using a simple random sampling method. Sample sizes for each facility were allocated proportionally. All cleaned & coded data were entered into Epi-info version 3.5.1 and analysis was carried out using SPSS version 20. Multivariate analysis was performed to determine predictors of pregnancy-induced hypertension at a p-value of <0.05. Result Women between 18 to 41 years old had participated in the study with the mean age of 26.00(SD ±4.42), and 25.87(SD ±5.02) for cases and controls respectively. Out of participants 21(30.4%) among cases and 21(15.2%) among controls had developed at least one complication following delivery. 12 (17.4%) and 8 (5.7%) foetal deaths were found in cases and controls groups respectively whereas 15.6% from cases and 3.6% from controls groups women gave birth to the foetus with intra-uterine growth retardation. Women gravidity AOR = 0.32 [95% CI (0.12 0.86)], Previous history of pregnancy-induced hypertension AOR = 22.50 [95% CI (14.95 16.52)] and educational status AOR = 0.32[95% CI (0.12, 0.85)] were identified as predictor of pregnancy-induced hypertension. Conclusion Women with a previous history of pregnancy-induced hypertension had increased risk of developing pregnancy-induced hypertension, whilst ≥ 3 previous pregnancies and informal educational status decrease odds of developing pregnancy-induced hypertension.


2019 ◽  
Vol 33 ◽  
pp. 158-163 ◽  
Author(s):  
Fereshteh Sanjarimoghaddam ◽  
Fatemeh Bahadori ◽  
Farnush Bakhshimoghaddam ◽  
Mohammad Alizadeh

2020 ◽  
Vol 9 (11) ◽  
pp. 3406 ◽  
Author(s):  
Jae Chol Choi ◽  
Sun-Young Jung ◽  
Una A. Yoon ◽  
Seung-Hun You ◽  
Myo-Song Kim ◽  
...  

Inhaled corticosteroids (ICS) could increase both the risk of coronavirus disease 2019 (COVID-19) and experiencing poor outcomes. To compare the clinical outcomes between ICS users and nonusers, COVID-19-related claims in the Korean Health Insurance Review and Assessment database were evaluated. To evaluate susceptibility to COVID-19 among patients with COPD or asthma, a nested case-control study was performed using the same database. In total, 7341 patients were confirmed to have COVID-19, including 114 ICS users and 7227 nonusers. Among 5910 patients who were hospitalized, death was observed for 9% of ICS users and 4% of nonusers. However, this association was not significant when adjusted for age, sex, region, comorbidities, and hospital type (aOR, 0.94; 95% CI, 0.43–2.07). The case-control analysis of COPD compared 640 cases with COVID-19 to 2560 matched controls without COVID-19, and the analysis of asthma compared 90 cases with COVID-19 to 360 matched controls without COVID-19. Use of ICS was not significantly associated with COVID-19 among patients with COPD (aOR, 1.02; 95% CI, 0.46–2.25) or asthma (aOR, 0.38; 95% CI, 0.13–1.17). Prior ICS use was not significantly associated with COVID-19 in patients with COPD or asthma, nor with clinical outcomes among patients with COVID-19.


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