Detection of fecal Bifidobacterium infantis in the first year of life in infants at risk of atopy supplemented with Lactobacillus rhamnosus GG and Bifidobacterium longum from birth till 6 months old

2007 ◽  
Vol &NA; ◽  
pp. S130 ◽  
Author(s):  
G.C. Yap ◽  
K.W. Mah ◽  
C. Lay ◽  
L.P.C. Shek ◽  
M. Aw ◽  
...  
2002 ◽  
Vol 110 (12) ◽  
Author(s):  
Janneane F Gent ◽  
Ping Ren ◽  
Kathleen Belanger ◽  
Elizabeth Triche ◽  
Michael B Bracken ◽  
...  

2008 ◽  
Vol 101 (11) ◽  
pp. 1722-1726 ◽  
Author(s):  
Samuli Rautava ◽  
Seppo Salminen ◽  
Erika Isolauri

A randomised, double-blind, placebo-controlled study was conducted to determine whether probiotics might be effective in reducing the risk of infections in infancy. Infants requiring formula before the age of 2 months were recruited from community well-baby clinics. Infant formula supplemented with the probioticsLactobacillus rhamnosusGG andBifidobacterium lactisBb-12 or placebo was administered daily until the age of 12 months. Incidence of early infections (before the age of 7 months) and incidence of recurrent (three or more) infections during the first year of life were recorded as the main outcome measures of the study. During the first 7 months of life, seven out of thirty-two (22 %) infants receiving probiotics and twenty out of forty (50 %) infants receiving placebo experienced acute otitis media (risk ratio (RR) 0·44 (95 % CI 0·21, 0·90);P = 0·014) and antibiotics were prescribed for ten out of thirty-two (31 %) infants receiving probiotics and twenty-four out of forty (60 %) infants receiving placebo (RR 0·52 (95 % CI 0·29, 0·92);P = 0·015). During the first year of life, nine out of thirty-two (28 %) infants receiving probiotics and twenty-two out of forty (55 %) infants receiving placebo encountered recurrent respiratory infections (RR 0·51 (95 % CI 0·27, 0·95);P = 0·022). These data suggest that probiotics may offer a safe means of reducing the risk of early acute otitis media and antibiotic use and the risk of recurrent respiratory infections during the first year of life. Further clinical trials are warranted.


2016 ◽  
Vol 21 ◽  
pp. 143-154
Author(s):  
Michelle Pascoe ◽  
Divya Bissessur ◽  
Pat Mayers

Background: Survival rates of premature infants have increased due to advances in medicine. Premature infants however, remain at risk for developmental delays including communication difficulties. The bonding and attachment experiences of premature infants and their parents are often challenged, further placing these infants at risk for communication difficulties. This study firstly aimed to explore mothers' perceptions of their premature infants' communication. The second aim was to explore the mothers' perceptions of their own role in the communication development of their infants.Methods: A descriptive, longitudinal study was conducted with two mother—infant dyads.Three visits took place in the first year of life. Subjective maternal reports were obtained through semi-structured interviews.Results: Differences in the two mothers' perceptions were noted. The mothers described helping their infants to communicate through physical contact and talking. Risk and protective factors for early communication development are discussed in relation to the findings.Conclusion: The findings support the need for a healthy mothereinfant relationship in the first few months of life. Health professionals should support premature infants and their families after discharge in order to help them interact with their infants and encourage attachment and bonding.


BMJ ◽  
1982 ◽  
Vol 284 (6321) ◽  
pp. 1011-1013 ◽  
Author(s):  
J J Cogswell ◽  
D F Halliday ◽  
J R Alexander

2009 ◽  
Vol 16 (10) ◽  
pp. 1521-1523 ◽  
Author(s):  
Richarda M. de Voer ◽  
Fiona R. M. van der Klis ◽  
Laetitia E. M. Niers ◽  
Ger T. Rijkers ◽  
Guy A. M. Berbers

ABSTRACT In The Netherlands, a single meningococcal serogroup C conjugate (MenCC) vaccination is administered to children at the age of 14 months. Here, we report the levels of MenC polysaccharide-specific antibodies in children at birth and at 3, 11, and 12 months of age and the presence of functional antibodies at 11 months of age, before infants receive their MenCC immunization. We observed a rapid decline in polysaccharide-specific antibodies after birth and no induction of naturally elicited polysaccharide-specific antibodies. Furthermore, at 11 months of age, no bactericidal antibodies are observed. These data indicate that these infants may be at risk in the period prior to MenCC immunization, if Neisseria meningitidis serogroup C starts to (re)circulate.


Author(s):  
C.M. Heinicke ◽  
N.R. Fineman ◽  
G. Ruth ◽  
S.L. Recchia ◽  
D. Guthrie ◽  
...  

2005 ◽  
Vol 161 (Supplement_1) ◽  
pp. S34-S34
Author(s):  
P F Rosenbaum ◽  
T M Hargrave ◽  
J L Abraham ◽  
J A Crawford ◽  
A Hunt ◽  
...  

2019 ◽  
Vol 53 (2) ◽  
pp. 1800998 ◽  
Author(s):  
Diane M. Gray ◽  
Dorottya Czovek ◽  
Lauren McMillan ◽  
Lidija Turkovic ◽  
Jacob A.M. Stadler ◽  
...  

Lower respiratory tract illness (LRTI) is a leading cause of mortality and morbidity in children. Sensitive and noninvasive infant lung function techniques are needed to measure risk for and impact of LRTI on lung health. The objective of this study was to investigate whether lung function derived from the intra-breath forced oscillation technique (FOT) was able to identify healthy infants at risk of LRTI in the first year of life.Lung function was measured with the novel intra-breath FOT, in 6-week-old infants in a South African birth cohort (Drakenstein Child Health Study). LRTI during the first year was confirmed by study staff. The association between baseline lung function and LRTI was assessed with logistic regression and odds ratios determined using optimal cut-off values.Of the 627 healthy infants with successful lung function testing, 161 (24%) had 238 LRTI episodes subsequently during the first year. Volume dependence of respiratory resistance (ΔR) and reactance (ΔX) was associated with LRTI. The predictive value was stronger if LRTI was recurrent (n=50 (31%): OR 2.5, ΔX), required hospitalisation (n=38 (16%): OR 5.4, ΔR) or was associated with wheeze (n=87 (37%): OR 3.9, ΔX).Intra-breath FOT can identify healthy infants at risk of developing LRTI, wheezing or severe illness in the first year of life.


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