Lifetime risk of stroke in young-aged and middle-aged Chinese population

Abstract Background: Peak expiratory flow (PEF), as an essential index used for screening and monitoring asthma, chronic obstructive pulmonary disease, and respiratory mortality especially in elderly, is recommended especially for low resource settings in low- and middle-income countries. However, few reports have focused on the reference of PEF in China, especially in the middle-aged and elderly. Thus, the aim of this study was to determine age- and sex-specific reference values of PEF in the middle-aged and older Chinese population.Methods: There were 11,717 participants included for reference value analysis and 11,340 participants were included for risk factor analysis. The PEF was measured using a peak flow meter in L/min. The distribution of PEF terciles stratified by sex and age were reported. Multiple linear regression analysis was used to determine the associations between risk factors and PEF.Results: The PEF was higher in men than women across all age subgroups. The value of PEF decreased with age in both men and women. Height, weight, handgrip strength, and household air pollution were positively associated with PEF, and age, waist circumference smoking status were negatively associated with PEF significantly in both men and women (all P <0.05). The mean values were 9.38 L/min and 64.12 L/min for men and women. Meanwhile, the prevalence of low PEF was 1.62% and 2.16% for men and women, respectively.Conclusions: Age- and sex-specific centiles of PEF for the middle-aged and older Chinese population were estimated. The reference values for low PEF were provided for epidemiological studies and clinical practice in the future. Interventions on lung function or respiratory disease should be pay more attention on factors associated with PEF.

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Association Between Sensory Loss and Falls Among Middle-Aged and Older Chinese Population: Cross-Sectional and Longitudinal Analyses

Frontiers in Medicine ◽

10.3389/fmed.2021.810159 ◽

2022 ◽

Vol 8 ◽

Author(s):

Yifan Zhou ◽

Yanping Hu ◽

Jianfeng Luo ◽

Yinwen Li ◽

Haiyun Liu ◽

...

Keyword(s):

Chinese Population ◽

Developed Countries ◽

Falls Prevention ◽

Sensory Loss ◽

Time Varying ◽

Middle Aged ◽

Cross Sectional ◽

Dual Sensory Loss ◽

Older Chinese ◽

The Impact

Introduction: Previous studies have suggested that sensory loss is linked to falls. However, most of these studies were cross-sectional designed, focused on single sensory loss, and were conducted in developed countries with mixed results. The current study aims to investigate the longitudinal relationship between hearing loss (HL), vision loss (VL) and dual sensory loss (DSL) with falls among middle-aged and older Chinese population over 7 years.Methods: The data was obtained from the China Health and Retirement Longitudinal Survey (CHARLS). In total, 7,623 Chinese older adults aged over 45 were included at baseline 2011 in this study. Self-reported falls and HL/VL/DSL were accepted. Other confounding variables included age, sex, BMI, educational level, marital status, various physical disorders and lifestyles. The impact of baseline sensory status on baseline prevalence of falls and incident falls over 7 years were assessed using logistic regression analyses. A logistic mixed model was used to assess the association between time-varying sensory loss with incident falls over 7 years after adjusted with multi-confounding factors.Results: Single and dual sensory loss groups had significantly higher prevalence of falls compared to no sensory loss (NSL) group (DSL: 22.4%, HL: 17.4%, VL: 15.7%, NSL: 12.3%). Baseline HL (OR: 1.503, 95% CI: 1.240–1.820), VL (OR: 1.330, 95% CI: 1.075–1.646) and DSL (OR: 2.061, 95% CI: 1.768–2.404) were significantly associated with prevalence of falls. For longitudinal observation over 7 years, baseline HL/DSL and persistence of all types of sensory loss were associated with incidence of falls. Time-varying HL (OR: 1.203, 95% CI: 1.070–1.354) and DSL (OR: 1.479, 95% CI: 1.343–1.629) were associated with incident falls after adjusted with multi-confounders, while VL was not.Conclusion: HL and DSL are significantly associated with both onset and increased incidence of falls over 7 year's observation in middle-aged and elderly Chinese population. Persistence or amelioration of sensory loss status could exert divergent influences on incidence of falls, which should be considered in the development of falls-prevention public health policies for aging population.

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Undernutrition in childhood resulted in bad dietary behaviors and the increased risk of hypertension in a middle-aged Chinese population

Journal of Developmental Origins of Health and Disease ◽

10.1017/s204017441800034x ◽

2018 ◽

Vol 9 (5) ◽

pp. 544-551

Author(s):

L. Zhang ◽

J. Sheng ◽

Y. Xuan ◽

P. Xuan ◽

J. Zhou ◽

...

Keyword(s):

Chinese Population ◽

Salt Intake ◽

Growth Period ◽

Dietary Behaviors ◽

Health Study ◽

Middle Aged ◽

Nutritional Improvement ◽

Increased Risk ◽

Good Nutrition ◽

Group 3

AbstractThis study was designed to explore the association between undernutrition in the growth period and cardiovascular risk factors in a middle-aged Chinese population. A total of 1756 subjects, aged 45–60 years, were invited to participate in the Hefei Nutrition and Health Study and divided into three groups according to their self-reported animal food intake in the growth period. Group 1, Group 2 and Group 3 were defined as undernutrition, nutritional improvement and the good nutrition group, respectively. In the three groups, the subjects in Groups 1 and 2 had more oil and salt intake (P<0.001), and less eggs and milk intake (P<0.001), when compared with the subjects in Group 3. After adjusting for age, education, smoking status and other confounding factors, it was found that male participants who experienced nutritional improvement before age 18 had higher risk of hypertension [odds ratio (OR)=1.68; 95% confidence intervals (CI): 1.05, 2.69] than those with good nutrition, and female participants with undernutrition (OR=1.52; 95% CI: 1.01, 2.29) and nutritional improvement (OR=1.68; 95% CI: 1.04, 2.69) before age 18 had a higher risk of hypertension than those with good nutrition. For diabetes, obesity, hypercholesterolemia and hypertriglyceridemia, our results did not found difference among the three groups both in male and female. Our findings indicated that nutritional deficiency in childhood was associated with bad dietary behaviors and a significantly increased risk of hypertension in middle age. Therefore, early adequate nutrition is very important for the prevention of non-communicable diseases later.

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