Changes of cardiovascular risk factors and their implications in subsequent birth cohorts of older adults in Germany: a life course approach

2007 ◽  
Vol 14 (6) ◽  
pp. 809-814 ◽  
Author(s):  
Elke Raum ◽  
Dietrich Rothenbacher ◽  
Michael Löw ◽  
Christa Stegmaier ◽  
Hartwig Ziegler ◽  
...  
Keyword(s):  
Risk Factors ◽  
Older Adults ◽  
Cardiovascular Risk ◽  
Life Course ◽  
Cardiovascular Risk Factors ◽  
Birth Cohorts ◽  
Life Course Approach ◽  
Subsequent Birth

Sex-specific associations of depressive symptoms and cardiovascular risk factors in older adults

2010 ◽  
Vol 14 (4) ◽  
pp. 405-410 ◽  
Author(s):  
Melissa C. Rice ◽  
Leslie I. Katzel ◽  
Shari R. Waldstein
Keyword(s):  
Risk Factors ◽  
Older Adults ◽  
Depressive Symptoms ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors

scholarly journals The Benefits of Physical Activity in Individuals with Cardiovascular Risk Factors: A Longitudinal Investigation Using fNIRS and Dual-Task Walking

2021 ◽  
Vol 10 (4) ◽  
pp. 579
Author(s):  
Deborah Talamonti ◽  
Thomas Vincent ◽  
Sarah Fraser ◽  
Anil Nigam ◽  
Frédéric Lesage ◽  
...  
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Older Adults ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Cognitive Performance ◽  
Dual Task ◽  
Gait Speed ◽  
Regular Physical Activity ◽  
Cortical Response

Cardiovascular fitness is linked to better executive functions, preserved gait speed, and efficient cortical activity. Older adults with cardiovascular risk factors (CVRFs) typically show poor cognitive performance, low physical fitness, and altered brain functioning compared with healthy individuals. In the current study, the impact of regular physical activity on cognition, locomotion, and brain functions was explored in a cohort of older adults with low or high CVRFs. Cortical activation of the frontal areas was investigated using functional Near-Infrared Spectroscopy (fNIRS) at baseline, at 6 months and at 12 months. Evoked cortical response and behavioral performance were assessed using the dual-task walking paradigm, consisting of three conditions: single cognitive task (2-back task), single walking task (walking), and dual-task (2-back whilst walking). Results show greater task-related cortical response at baseline in individuals with high CVRFs compared to those with low CVRFs. Moreover, participants with high CVRFs benefitted the most from participating in regular physical activity, as their cortical response decreased at the 12-month follow-up and became comparable to that of participants with low CVRFs. These changes were observed in conjunction with improved cognitive performance and stable gait speed throughout the 12-month period in both groups. Our findings provide evidence that participation in regular physical activity may be especially beneficial in individuals with CVRFs by promoting brain and cognitive health, thus potentially contributing to prevention of cognitive decline. Future research may explore whether such effects are maintained in the long-term in order to design ad-hoc interventions in this specific population.

scholarly journals Association between ApoE ε4 Carrier Status and Cardiovascular Risk Factors on Mild Cognitive Impairment among Mexican Older Adults

2021 ◽  
Vol 11 (1) ◽  
pp. 68
Author(s):  
Sara G. Aguilar-Navarro ◽  
Itzel I. Gonzalez-Aparicio ◽  
José Alberto Avila-Funes ◽  
Teresa Juárez-Cedillo ◽  
Teresa Tusié-Luna ◽  
...  
Keyword(s):  
Risk Factors ◽  
Older Adults ◽  
Cognitive Impairment ◽  
Cardiovascular Risk ◽  
Mild Cognitive Impairment ◽  
Cardiovascular Risk Factors ◽  
Apoe Genotype ◽  
Carrier Status ◽  
Apoe Ε4 ◽  
Increased Risk

Mild cognitive impairment (MCI) (amnestic or non-amnestic) has different clinical and neuropsychological characteristics, and its evolution is heterogeneous. Cardiovascular risk factors (CVRF), such as hypertension, diabetes, or dyslipidemia, and the presence of the Apolipoprotein E ε4 (ApoE ε4) polymorphism have been associated with an increased risk of developing Alzheimer’s disease (AD) and other dementias but the relationship is inconsistent worldwide. We aimed to establish the association between the ApoE ε4 carrier status and CVRF on MCI subtypes (amnestic and non-amnestic) in Mexican older adults. Cross-sectional study including 137 older adults (n = 63 with normal cognition (NC), n = 24 with amnesic, and n = 50 with non-amnesic MCI). Multinomial logistic regression models were performed in order to determine the association between ApoE ε4 polymorphism carrier and CVRF on amnestic and non-amnestic-MCI. ApoE ε4 carrier status was present in 28.8% participants. The models showed that ApoE ε4 carrier status was not associated neither aMCI nor naMCI condition. The interaction term ApoE ε4 × CVRF was not statistically significant for both types of MCI. However, CVRF were associated with both types of MCI and the association remained statistically significant after adjustment by sex, age, and education level. The carrier status of the ApoE genotype does not contribute to this risk.

scholarly journals Life Course Models of Socioeconomic Position and Cardiovascular Risk Factors: 1946 Birth Cohort

2011 ◽  
Vol 21 (8) ◽  
pp. 589-597 ◽  
Author(s):  
Emily T. Murray ◽  
Gita D. Mishra ◽  
Diana Kuh ◽  
Jack Guralnik ◽  
Stephanie Black ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Life Course ◽  
Cardiovascular Risk Factors ◽  
Birth Cohort ◽  
Socioeconomic Position

Uric acid may be protective against cognitive impairment in older adults, but only in those without cardiovascular risk factors

2017 ◽  
Vol 89 ◽  
pp. 15-19 ◽  
Author(s):  
Busra Tuven ◽  
Pinar Soysal ◽  
Gulcin Unutmaz ◽  
Derya Kaya ◽  
Ahmet Turan Isik
Keyword(s):  
Risk Factors ◽  
Older Adults ◽  
Uric Acid ◽  
Cognitive Impairment ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors

scholarly journals Web‐based assessment of cardiovascular risk factors and cognition in older adults: Findings from the Brain eHealth feasibility study

2020 ◽  
Vol 16 (S10) ◽  
Author(s):  
Kristine Yaffe ◽  
Allison R Kaup ◽  
Amber L Bahorik ◽  
Xochitl Butcher ◽  
Mouna Attarha ◽  
...  
Keyword(s):  
Risk Factors ◽  
Older Adults ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Feasibility Study ◽  
Web Based ◽  
The Brain
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