There are more than 80 million users of soft contact lenses in the world - 10-15 % of the population. The prevalence of meibomyus gland dysfunction is 43-61 % with the prevalence of obstructive form and the development of lipodeficiency in lacrimal film. At the same time, the use of traditional tear substitutes based on hyaluronic acid is ineffective and the problem of finding a tear substitute with exposure to all 3 layers of lacrimal film becomes relevant. Nanoemulsion “Cationorm” is created as a means of pathogenetic therapy of dry eye syndrome against the background of lipodeficiency, however, there weren't any studies of its effectiveness in obstructive form of meibomyus gland dysfunction among users of soft contact lenses. We examined 3 layers of lacrimal film with the help of Norn's sample with determination of time of lacrimal film break, bio-measurement of lacrimal meniscus and biomicoscopy of eyelid edge region at painting of lissamino-om green. The study involved 28 young carriers of silicone-hydrogel contact lenses with signs of obstructive form of meibomyus gland dysfunction, who we divided into two groups: a control group used to eliminate the symptoms of a hyaluronic acid-based tear substitute, and an experimental group using the drug “Cationorm”. We revealed prolonged effect of nanoemulsion “Cationorm” on all three layers of lacrimal film, which hasn't only symptom lacrimal, but has pathogenetic therapeutic delayed effect among users of soft contact lenses with obstructive form of dysfunction of meibomyum glands, and nanostimer of lipid microspheres provides full compatibility even with material of silicone-hydrogel soft contact lenses. We proved the protective effect of the preparation on ocular epithelium cells.
Evaluation of the Lubricating Effect of Hyaluronic Acid on Contact Lenses Using a Pendulum-Type Friction Tester Under Mimicking Physiological Conditions
