The Difference in Intraocular Pressure Readings Between 3 Applanation Tonometers is Independent of Central Corneal Thickness, in Glaucomatous and Nonglaucomatous Eyes

2014 ◽  
Vol 23 (9) ◽  
pp. 620-623
Author(s):  
Caroline Baily ◽  
Ian Dooley ◽  
Niamh Collins ◽  
Marie Hickey-Dwyer
Keyword(s):  
Intraocular Pressure ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
The Difference

Icare versus Goldmann in a randomised middle-aged population

2020 ◽  
pp. 112067212092138
Author(s):  
Katri Stoor ◽  
Elina Karvonen ◽  
Pasi Ohtonen ◽  
M Johanna Liinamaa ◽  
Ville Saarela
Keyword(s):  
Intraocular Pressure ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Intraclass Correlation ◽  
Population Based ◽  
Rebound Tonometer ◽  
Goldmann Applanation Tonometer ◽  
Applanation Tonometer ◽  
Screening Study ◽  
The Difference

Purpose The aim of this study was to compare the measurements of intraocular pressure by two tonometers, the Icare rebound tonometer and the Goldmann applanation tonometer, in a randomised screening study. The influence of refraction and central corneal thickness on the measurements was also evaluated. Methods Intraocular pressure was measured with rebound tonometer and Goldmann applanation tonometer in 1266 participants; refraction and central corneal thickness were also determined. One randomised eye of each participant was selected for this report’s analysis. A Bland–Altman plot was used to compare the values obtained with the two devices. Results The correlation between rebound tonometer and Goldmann applanation tonometer was good: the intraclass correlation coefficient (r) between the two methods was 0.735 ( p < 0.001). The mean difference (rebound tonometer–Goldmann applanation tonometer) was 0.11 ± 2.3 mmHg. The difference was not statistically significant (95% confidence interval: 0.11 to 0.13, p = 0.09). With increasing central corneal thickness, not only did intraocular pressure values with both devices increase, but the difference between them also increased. Refraction (spherical equivalent) did not influence intraocular pressure or the rebound tonometer–Goldmann applanation tonometer difference. However, high astigmatism (≥2D) exerted an influence on intraocular pressure values taken with Goldmann applanation tonometer. Conclusion Measurements with rebound tonometer and Goldmann applanation tonometer are relatively uniform although rebound tonometer slightly overestimated intraocular pressure. Both rebound tonometer and Goldmann applanation tonometer and the difference between these devices were affected by central corneal thickness but not by refraction. Higher astigmatism affected Goldmann applanation tonometer more than rebound tonometer. It is concluded that rebound tonometer is a reliable method for measuring intraocular pressure in a population-based screening study.

scholarly journals A comparative study of central corneal thickness (CCT) and intraocular pressure (IOP) in University of KwaZulu-Natal students of Black and Indian ethnicity*

2012 ◽  
Vol 71 (4) ◽  
Author(s):  
Z. Sardiwalla ◽  
D. Moodley ◽  
T. Ndawonde ◽  
A. Madikizela ◽  
N. Ngobese ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Ethnic Groups ◽  
Black Males ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Total Sample ◽  
Black Females ◽  
The Mean ◽  
The Difference ◽  
The Right

Thisstudy compared central corneal thickness (CCT) and intraocular pressure (IOP) of Black and Indian students from the University of Kwa-Zulu-Natal. Two hundred (100 Black and 100 Indi-an) participants of both genders aged 18-25 years (mean and standard deviation; 20.1±1.6 years) participated in this study. CCT and IOP were measured for the right eye of each participant using a Tono-Pachymeter (NT530P) and a Goldmann applanation tonometer (GAT) respectively. Data was analyzed with descriptive, t-test and Pearson’s cor-relation statistics. In the total sample (N = 200), the mean CCT value was 519.5 ± 38.6 μm and CCT was higher in the Indians (526.5 ± 37.2 µm) than in the Blacks (512.4 ± 38.9 µm) (p = 0.01).  Also, it was higher in the females (522.3 µm) than in males (516.7 µm), but the difference was insignificant (p = 0.07). The mean CCT was higher in the Indian males (520.1 µm) than in the Black males (513.2 µm), but the difference was insignificant (p=0.39).  However, it was significantly higher in the Indian females (533 µm) than in the Black females (511.6 µm) (p = 0.003). In the total sample, the mean IOP was 14.6 mmHg and IOP was greater in Indiansthan Blacks (mean = 15.3 ± 2.9 mmHg and 13.8 ± 2.6 mmHg respectively) (p = 0.01). Also, the mean IOP (N = 200) value was slightly higher in the females (14.7 mmHg) than in males (14.5 mmHg) (p = 0.51). The mean IOP was higher in the Indian males (15.0 mmHg) than in the Black males (14.0 mmHg) (p = 0.07) and the mean IOP value was higher in the Indian females (15.7 mmHg) than in the Black females (13.6 mmHg) (p < 0.001). The higher mean IOP value in the Indian than Black participants was attributed to the higher mean CCT values. A positive, but inconsistent association between CCT and IOP was found in this study, the coefficient in the total sample (r = 0.382, p = 0.000), in the Blacks (r = 0.196, p = 0.05) and in Indians (r = 0.498, p = 0.000). A national population study comparing CCT and IOP in the various South African ethnic groups is recommended. Cognizance of these differences should be taken in the diagnoses of glaucoma in these ethnic groups. (S Afr Optom 2012 71(4) 171-177)

scholarly journals Comparison of intraocular pressure and central corneal thickness in non-glaucomatous North- East Indian tribals versus general Indians

2019 ◽  
Vol 16 (3) ◽  
pp. 144-152
Author(s):  
Tanie Natung ◽  
Prasanta Kumar Goswami ◽  
Avonuo Keditsu ◽  
Wakaru Shullai
Keyword(s):  
Intraocular Pressure ◽  
Central Corneal Thickness ◽  
Linear Regression Analysis ◽  
Corneal Thickness ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
East Indian ◽  
North East ◽  
The Mean ◽  
The Difference

Purpose: To compare the intraocular pressure (IOP) and central corneal thickness (CCT) of non-glaucomatous North-East (NE) Indian tribals and general Indians.  Materials and methods: In a prospective, cross-sectional study, the IOP and CCT of non-glaucomatous NE Indian tribals (n = 50) and non-glaucomatous general Indians (n = 50) were compared. Glaucoma was ruled out by history, detailed ocular examinations, and investigations. Results: There was very good correlation between the CCT and IOP values of right and left eyes (p = 0.940 and 0.847, respectively). The difference in the IOP values in the two groups was not statistically significant (p = 0.312 for Oculus Dexter [OD], p = 0.400 for Oculus Sinister [OS]). Similarly, the difference in the CCT values in the two groups was not statistically significant (p = 0.736 for OD and 0.613 for OS). The mean CCT and IOP OD for the whole population was 530.50 ± 35.42 μm and 13.80 ± 2.760 mmHg, respectively. By linear regression analysis, the IOP OD of the whole population had good correlation with CCT OD of the whole population (adjusted r2 = 0.084, p = 0.002), but not with age (adjusted r2=0.000, p=0.314) and sex (adjusted r2 = 0.010, p = 0.163). Similarly, CCT OD for the whole population did not have good correlation with age (adjusted r2 = -0.009, p = 0.762) and sex (adjusted r2 = -0.007, p = 0.603). Conclusions: In this study of individuals with normal corneas and without glaucoma, no racial variation was found in the CCT and IOP values of the two groups. The IOP OD of whole population had good correlation with CCT, but not with age and sex. There was good correlation between OD and OS values of IOP and CCT.

Clinical Profile of Myopic Patients as a Risk Factor for Primary Open Angle Glaucoma - A Prospective Observational Study in Gorakhpur, Uttar Pradesh

2021 ◽  
Vol 8 (33) ◽  
pp. 3084-3089
Author(s):  
Ram Kumar Jaiswal ◽  
Ramyash Singh Yadav ◽  
Mridula Ranjan ◽  
Dipti Wahi ◽  
Chiranji Rai
Keyword(s):  
Risk Factor ◽  
Intraocular Pressure ◽  
Observational Study ◽  
High Myopia ◽  
Central Corneal Thickness ◽  
Prospective Observational Study ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Corneal Thickness ◽  
Open Angle

BACKGROUND Myopia is a complex trait including both genetic and environmental factors as well as gene-environment interactions. It has been recognized as a risk factor for development of glaucoma. Both Myopia and raised IOP are known to increase mechanical stress at optic nerve head leading to glaucomatous nerve damage. This study intends to evaluate the clinical profile of myopic subjects and its correlation with Primary open angle glaucoma (POAG). METHODS A prospective observational study done from November 2019 to December 2020 after taking proper informed consent and ethical clearance. 164 eyes of 96 patients studied were divided into three groups, Group 1: low myopia (< -3.00D), Group 2: moderate myopia (-3.00 D to -5.75 D), Group 3: high myopia (≥ -6.00 D). A complete ocular examination was performed. Intraocular pressure was measured using Goldmann applanation tonometer. Visual field analysis using Humphrey automated perimetry was done in patients with suspected primary open angle glaucoma (POAG). Angle parameters and central corneal thickness (CCT) were measured using anterior segment optical coherence tomography (AS-OCT). RESULTS 164 eyes of 96 Myopic subjects were studied with no dropout during study period. Mean age was 46.05 yr. (range: 25-75 yr.). The refraction ranged from -0.50 DS to -17.00 DS. There was no statistically significant difference between Intraocular pressure (IOP), Central corneal thickness (CCT), corrected IOP and Nasal and Temporal Trabecular-iris Angle (TIA) between male and female of same age group. Mean IOP and mean CCT were found to vary significantly with age and with higher degree of myopia. Corrected IOP, Nasal and Temporal TIA increase significantly with higher degree of myopia. Cup-disc ratio (CDR) was found to be significantly higher in patients with moderate to high degree of Myopia. CONCLUSIONS Myopia is an important risk factor for development of primary open angle glaucoma, with its incidence increasing in patients with moderate to high myopia. KEYWORDS Myopia, Primary Open Angle Glaucoma, Intraocular Pressure, Central Corneal Thickness, Trabecular Iris Angle

scholarly journals Correlation between central corneal thickness and intraocular pressure peak and fluctuation during the water drinking test in glaucoma patients

Clinics ◽  
2010 ◽  
Vol 65 (10) ◽  
pp. 967-970 ◽  
Author(s):  
Rafael Lacerda Furlanetto ◽  
Antonio Carlos Facio Jr ◽  
Marcelo Hatanaka ◽  
Remo Susanna Junior
Keyword(s):  
Intraocular Pressure ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Water Drinking ◽  
Pressure Peak ◽  
Drinking Test ◽  
Water Drinking Test

scholarly journals Intraocular Pressure Changes Following Different Keratoplasty Techniques and Association with Cornea Parameters and anterior Chamber Depth

2021 ◽  
Author(s):  
Gülşah Gümüş ◽  
cigdem altan ◽  
yusuf yildirim ◽  
nilay kandemir besek ◽  
selim genç ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Anterior Chamber ◽  
Corneal Thickness ◽  
Anterior Chamber Depth ◽  
Early Postoperative Period ◽  
Lamellar Keratoplasty ◽  
Deep Anterior Lamellar Keratoplasty ◽  
Anterior Lamellar Keratoplasty ◽  
The Difference ◽  
Pressure Changes

Abstract Purpose To evaluate early intraocular pressure (IOP) changes following different keratoplasty techniques and to investigate the relationship between corneal thickness (CT), keratometry values, anterior chamber depth (ACD) and IOP changes. Methods We included patients who underwent penetrating keratoplasty (PK), deep anterior lamellar keratoplasty (DALK) and Descemet membrane endothelial keratoplasty (DMEK). ACD, CT, and keratometry measurements were repeated postoperatively at hour 24, week 1, and month 1. IOP measurements were repeated at postoperative hours 6 and 24, week 1, and month 1 by Tono-Pen XL. Results Twenty-two patients underwent PK, 12 patients underwent DALK, and 19 patients underwent DMEK. The difference between the IOP preoperatively and 6 hours postoperatively and between the IOP preoperatively and 24 hours postoperatively were statistically significant in the three types of surgery (p < 0.05 for each). The difference between preoperative and postoperative week 1 IOP was statistically significant only in the PK group (p = 0.023). When the IOP was compared between the three types of surgeries, the IOP at postoperative week 1 in the PK group was significantly higher than the DALK and DMEK groups (p = 0.021). There was no correlation between ACD, corneal thickness, K values, and IOP in any group. Conclusion IOP may increase in all types of keratoplasty during the first hours after surgery, but PK has a risk of high IOP longer in the early postoperative period. PK patients should be followed more carefully during postoperative week 1 to check for an increase in IOP.

scholarly journals Effect of Desonide 0.25% Ophthalmic Solution on Central Corneal Thickness and Intraocular Pressure of Patients with Allergic Conjunctivitis

1970 ◽  
Vol 12 (3) ◽  
pp. 156-158
Author(s):  
Ozlem Gurses Sahin
Keyword(s):  
Intraocular Pressure ◽  
Allergic Conjunctivitis ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Ophthalmic Solution ◽  
Applanation Tonometry ◽  
Goldmann Applanation Tonometry ◽  
Mean Values ◽  
Conjunctival Hyperaemia ◽  
Significant Difference

Aim: To evaluate whether a significant difference exists between the initial and final mean central corneal thickness that might affect Goldmann applanation tonometer recordings of patients with allergic conjunctivitis treated with desonide 0.25% ophthalmic solution, and to determine the effect of desonide on intraocular pressure by using adjusted intraocular pressure values.Methods: This double-blind randomised placebo-controlled trial enrolled 30 patients (60 eyes) with allergic conjunctivitis. Patients were randomly assigned to receive desonide to 1 eye (study eye) and preservative-free tear supplement (Tears Naturale Free®) to the other eye (control eye) 3 times daily for 3 weeks. Goldmann applanation tonometry and central corneal thickness of both eyes were recorded on the day of presentation and 3 weeks later.Results: Regression of itching, tearing, conjunctival hyperaemia, and tarsal conjunctival papillary reaction were noted in the study eyes after 3 weeks of treatment. The control eyes showed mild regression of pruritis, tearing, conjunctival hyperaemia, and tarsal conjunctival papillary reaction after 3 weeks. There was a significant difference between the initial and final mean central corneal thickness values for the study eyes (p = 0.003). There were no statistically significant differences between the initial and final mean values of Goldmann applanation tonometry and adjusted intraocular pressure for the study eyes. No statistically significant differences were found between the initial and final mean values of any of the parameters for the control eyes.Conclusion: Inflammation-induced increase in central corneal thickness of patients with allergic conjunctivitis treated with desonide showed statistically significant regression. However, this regression did not significantly affect Goldmann applanation tonometry and adjusted intraocular pressure values of the treated eyes.

scholarly journals Effect of Acute Increases in Intraocular Pressure on Corneal Pachymetry in Rabbit Eyes Treated with Timolol Maleate

2018 ◽  
Vol 12 (1) ◽  
pp. 314-321
Author(s):  
Cristina Sánchez-Barahona ◽  
Gema Bolívar ◽  
Dimitrios G. Mikropoulos ◽  
Anastasios G. Konstas ◽  
Miguel A. Teus
Keyword(s):  
Intraocular Pressure ◽  
Anterior Chamber ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Rabbit Model ◽  
Controlled Study ◽  
Control Group ◽  
Study Group ◽  
Timolol Maleate

Objective: To evaluate in an in vivo rabbit model, the effect of topical timolol maleate therapy on the central corneal thickness response to acute intraocular pressure increases. Method: In this prospective and interventional controlled study, the central corneal thickness and intraocular pressure were measured in vivo in 12 rabbit eyes treated with topical timolol maleate for 1 month and in 12 controls at baseline, and after the intraocular pressure (measured by direct cannulation of the anterior chamber) was increased to 15 and 30 mmHg using a forced saline infusion into the anterior chamber. Results: There were no significant differences in the basal central corneal thickness values (control group, 373.2±12.9 µm; study group, 377.5±19.2 µm, p=0.5) or the central corneal thickness values when the intraocular pressure was increased to 15 mmHg (control group, 335.2±14.3 µm; study group, 330.0±32.1 µm, p=0.6) and to 30 mmHg (study group, 318.8±25.3 µm; control group, 329.8±21.0 µm, p=0.3). Conclusion: Rabbit corneas treated with topical timolol maleate for 1 month did not show a strain response to acute intraocular pressure increases that differed from control eyes. This is in contrast to a previous finding in which rabbit eyes treated with prostaglandin analogues had a greater decrease in central corneal thickness in response to a sudden intraocular pressure increase compared with untreated corneas.

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