The mean platelet volume is decreased in patients with mild head trauma and brain injury

2013 ◽  
Vol 24 (7) ◽  
pp. 780-783 ◽  
Author(s):  
Giuseppe Lippi ◽  
Andrea Carbucicchio ◽  
Mario Benatti ◽  
Gianfranco Cervellin
Author(s):  
Bulent Ozdemir ◽  
Ayhan Kanat ◽  
Hizir Kazdal ◽  
Osman Ersagun Batcik ◽  
Vacide Ozdemir ◽  
...  

Objective: Prediction of mortality in the patient of the intensive care unit is essential. It was aimed to study the mortality predictive value of mean platelet volume (MPV) in patients with severe head trauma. Study design: The mean platelet volumes were measured in patients with head injury managed intensive care unit between 1 December 2017 and 1 January 2019 at admission and exitus date. Methods: The main outcome variable was mortality due to the traumatic event of patients. 43 patients with head trauma admitted to the intensive care unit during the study period. 17 patients died (Group I), 26 survived (Group II). Results: There was not an association between MPV and mortality at admission. However, Cox regression analysis showed that late MPV (at exitus or discharged date), WBC at admission, and age increase the mortality rate 1,770, 1,202, 1,052 times, respectively. Conclusion: The present study shows that MPV may be a useful predictor of mortality in the patient with severe head trauma. More detailed studies are needed.


1987 ◽  
Vol 57 (01) ◽  
pp. 55-58 ◽  
Author(s):  
J F Martin ◽  
T D Daniel ◽  
E A Trowbridge

SummaryPatients undergoing surgery for coronary artery bypass graft or heart valve replacement had their platelet count and mean volume measured pre-operatively, immediately post-operatively and serially for up to 48 days after the surgical procedure. The mean pre-operative platelet count of 1.95 ± 0.11 × 1011/1 (n = 26) fell significantly to 1.35 ± 0.09 × 1011/1 immediately post-operatively (p <0.001) (n = 22), without a significant alteration in the mean platelet volume. The average platelet count rose to a maximum of 5.07 ± 0.66 × 1011/1 between days 14 and 17 after surgery while the average mean platelet volume fell from preparative and post-operative values of 7.25 ± 0.14 and 7.20 ± 0.14 fl respectively to a minimum of 6.16 ± 0.16 fl by day 20. Seven patients were followed for 32 days or longer after the operation. By this time they had achieved steady state thrombopoiesis and their average platelet count was 2.44 ± 0.33 × 1011/1, significantly higher than the pre-operative value (p <0.05), while their average mean platelet volume was 6.63 ± 0.21 fl, significantly lower than before surgery (p <0.001). The pre-operative values for the platelet volume and counts of these patients were significantly different from a control group of 32 young males, while the chronic post-operative values were not. These long term changes in platelet volume and count may reflect changes in the thrombopoietic control system secondary to the corrective surgery.


2014 ◽  
Vol 99 (Suppl 2) ◽  
pp. A144.4-A145
Author(s):  
M Tekin ◽  
C Konca ◽  
Z Kahramaner ◽  
A Erdemir ◽  
A Gulyuz ◽  
...  

Platelets ◽  
2009 ◽  
Vol 20 (1) ◽  
pp. 58-63 ◽  
Author(s):  
Mehmet Yazici ◽  
Ahmet Kaya ◽  
Yasemin Kaya ◽  
Sinan Albayrak ◽  
Hakan Cinemre ◽  
...  

Author(s):  
Gul Nihal Buyuk ◽  
Z.Asli Oskovi-Kaplan ◽  
Aysegul Oksuzoglu ◽  
H.Levent Keskin

Abstract Objectives The aim of our study was to analyze the mean platelet volume levels as a potential marker of altered placentation in intrauterine growth restriction (IUGR) cases. Methods A total of 126 term singleton pregnant women with IUGR fetuses and 345 healthy pregnant controls were recruited and compared. Results The mean platelet volume was significantly higher in the IUGR group (10.8±0.9 fl) than the control group (9.9±1.1 fl) (p=0.03). The mean hemoglobin was lower in IUGR group (11.3 (8.3–14.5) g/dl) than the control group (11.9 (8.2–13.0) g/dl) (p=0.04). The optimal cut-off MPV for prediction of IUGR was ≥10.55 fl, with a sensitivity of 59% and a specificity of 75%. Conclusion Increased MPV levels in term pregnant women may be particularly helpful for discrimination and prediction of high-risk fetuses when IUGR is suspected.


2013 ◽  
Vol 31 (3) ◽  
pp. 215 ◽  
Author(s):  
Halil Ciftci ◽  
Ercan Yeni ◽  
Mehmet Demir ◽  
Ismail Yagmur ◽  
Kemal Gümüş ◽  
...  

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