Are Emerging Infectious Diseases the Most Significant Global Health Concern for Nurses?

2012 ◽  
Vol 37 (5) ◽  
pp. 288-289 ◽  
Author(s):  
Kathleen Leask Capitulo ◽  
Denise M. Korniewicz ◽  
Carol M. Baldwin
2011 ◽  
Vol 236 (8) ◽  
pp. 897-898 ◽  
Author(s):  
Timothy P Endy ◽  
Rosemary Rochford ◽  
Kwok-Yung Yuen ◽  
Huan-Yao Lei

2012 ◽  
Vol 33 (4) ◽  
pp. 137
Author(s):  
John MacKenzie ◽  
Martyn Jeggo

Global health security has become a major concern, particularly the threats to human and animal health from the emergence and re-emergence of epidemic-prone infectious diseases, as well as the significant and growing impact of these outbreaks on national and international economies. It has long been known that many of these diseases can cross the species barrier between humans, wildlife and domestic animals, and indeed over 70% of novel emerging infectious diseases are zoonotic, that is, have their origins in animal reservoirs. There have been many recent examples of this trend, the most dramatic being recently the SARS epidemic ? the first major threat to global health from a novel zoonotic disease in the new Millennium. Other recent examples include the H1N1 influenza virus pandemic; the spread of Nipah virus into Bangladesh and India; and perhaps the most important of all, the ongoing concerns of a highly virulent influenza pandemic due to avian influenza virus (H5N1).


npj Vaccines ◽  
2020 ◽  
Vol 5 (1) ◽  
Author(s):  
Drishya Kurup ◽  
Christoph Wirblich ◽  
Holly Ramage ◽  
Matthias J. Schnell

Abstract The recently emerged coronavirus SARS-CoV-2, the causative agent of COVID-19, is rapidly spreading in the world. The exponentially expanding threat of SARS-CoV-2 to global health highlights the urgent need for a vaccine. Herein we show the rapid development of a novel, highly efficient, and safe COVID-19 vaccine using a rabies virus-based vector that has proven to be an efficient vaccine against several emerging infectious diseases. This study reports that both a live and an inactivated rabies virus containing the SARS-CoV-2 spike S1 protein induces potent virus-neutralizing antibodies at much higher levels than seen in the sera of convalescent patients. In summary, the results provided here warrant further development of this safe and established vaccine platform against COVID-19.


Author(s):  
Jonathan T. Vu ◽  
Benjamin K. Kaplan ◽  
Shomesh Chaudhuri ◽  
Monique K. Mansoura ◽  
Andrew W. Lo

AbstractRecent outbreaks of infectious pathogens such as Zika, Ebola, and COVID-19 have underscored the need for the dependable availability of vaccines against emerging infectious diseases (EIDs). The cost and risk of R&D programs and uniquely unpredictable demand for EID vaccines have discouraged vaccine developers, and government and nonprofit agencies have been unable to provide timely or sufficient incentives for their development and sustained supply. We analyze the economic returns of a portfolio of EID vaccine assets, and find that under realistic financing assumptions, the expected returns are significantly negative, implying that the private sector is unlikely to address this need without public-sector intervention. We have sized the financing deficit for this portfolio and propose several potential solutions, including price increases, enhanced public-private partnerships, and subscription models through which individuals would pay annual fees to obtain access to a portfolio of vaccines in the event of an outbreak.


Author(s):  
Ehsan Mostafavi ◽  
Abdolmajid Ghasemian ◽  
Abubakar Abdinasir ◽  
Seyed Alireza Nematollahi Mahani ◽  
Salman Rawaf ◽  
...  

Background: Countries in the World Health Organization (WHO) Eastern Mediterranean Region (EMR) are predisposed to highly contagious, severe and fatal, emerging infectious diseases (EIDs), and re-emerging infectious diseases (RIDs). This paper reviews the epidemiological situation of EIDs and RIDs of global concern in the EMR between 2001 and 2018. Methods: To do a narrative review, a complete list of studies in the field was we prepared following a systematic search approach. Studies that were purposively reviewed were identified to summarize the epidemiological situation of each targeted disease. A comprehensive search of all published studies on EIDs and RIDs between 2001 and 2018 was carried out through search engines including Medline, Web of Science, Scopus, Google Scholar, and ScienceDirect. Results: Leishmaniasis, hepatitis A virus (HAV) and hepatitis E virus (HEV) are reported from all countries in the region. Chikungunya, Crimean Congo hemorrhagic fever (CCHF), dengue fever, and H5N1 have been increasing in number, frequency, and expanding in their geographic distribution. Middle East respiratory syndrome (MERS), which was reported in this region in 2012 is still a public health concern. There are challenges to control cholera, diphtheria, leishmaniasis, measles, and poliomyelitis in some of the countries. Moreover, Alkhurma hemorrhagic fever (AHF), and Rift Valley fever (RVF) are limited to some countries in the region. Also, there is little information about the real situation of the plague, Q fever, and tularemia. Conclusion: EIDs and RIDs are prevalent in most countries in the region and could further spread within the region. It is crucial to improve regional capacities and capabilities in preventing and responding to disease outbreaks with adequate resources and expertise.


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