scholarly journals Bacterial Vaginosis and Its Association with Incident Trichomonas Vaginalis Infections

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Arlene C. Seña ◽  
Linda A. Goldstein ◽  
Gilbert Ramirez ◽  
Austin Parish ◽  
R. Scott McClelland
Keyword(s):  
Bacterial Vaginosis ◽  
Trichomonas Vaginalis

Protozoynye invasion of urogenital system in combine with bacterial vaginosis agents by women of fertil age and their sexual partners

2018 ◽  
pp. 100-106
Author(s):  
P.V. Fedorich ◽  
Keyword(s):  
Bacterial Vaginosis ◽  
Giardia Lamblia ◽  
Trichomonas Vaginalis ◽  
Empiric Therapy ◽  
Modern Medicine ◽  
Original Method ◽  
Sexual Partners ◽  
Urogenital System ◽  
Chronic Infections ◽  
Pentatrichomonas Hominis

Study of protozoyny invazions of the uroganital system with combination of microorganisms which are associated with bacterial vaginosis by women of fertil age and their sexual partners men is perspective direction of modern medicine. The development of this direction can increase the level of diagnostic inspection of patients by transmissible mainly sexual way infections and improve of efficiency of their treatment. The objective: exposure of combine defeats of uroganital system with different kinds of trichomonas or lamblias and microorganisms which are associated with bacterial vaginosis, for the women of fertil age and their sexual partners – men. All patients have infections, transmissible mainly sexual way with a chronic process and their treatment. Materials and methods. The special research of biomaterial, taken from the urogenital system of women of fertil age and their sexual partners-men, patients infections, transmissible mainly sexual way with a chronic process is conducted. 198 patients were inspected in clinic. Used the method of PCR, amplifier of DT-96, reagents of «Femoflor-16», praymeris for the indication of Trichomonas vaginalis, Trichomonas tenax, Pentatrichomonas hominis and Giardia lamblia. Results. Protozoyny invasions of the urogenital system determined at 88 (44.4%) of patients. At 77 (38.8%) from them determined the differet kinds of trichomonadies: Trichomonas tenax – at 41 (20.7%), Pentatrichomonas hominis – at 28 (14.1%), Trichomonas vaginalis – at 8 (4%). Giardia lamblia determined from 11 patients (5.6%). For 92% inspected patients with a protozoal invasions were determined the increassng of indexes of microflora, associated with bacterial vaginosis. The treatment of combine pathology of urogenital system which are caused different kinds trichomonades and microorganisms, which associated with BV, were conducted with etiotropic therapy. Seknidox used 2 tablets one time per day during 5 days. Orcipol used 1 tablets 3 or 2 times per a day (depending on weight) during 10 days. In research took part 56 patients with chronic ITSW. By 54 patients (96.4%) were eliminated of trichomonas. The normalization microflora’s level is attained for a 31 (57.4%) patient. Decrease of mocroflora’s, which associated with BV is marked by 24 patients (42.6%). Conclusions. This original method of treatment, is effective, has satisfactory bearableness and can be recommended for empiric therapy of combined pathology of urogenital system, caused of protozoyny invasions (different kinds of trichomonas) and microorganisms, associated with bacterial vaginosis, for the women of fertil age and their sexual partners with chronic infections, transmissible mainly sexual a way. This agents have a certain role in development of diseases of the urogenital system. Key words: Trichomonas vaginalis, Trichomonas tenax, Pentatrichomonas hominis, Giardia lamblia, invasion, fertil age.

scholarly journals Evaluation of Association between Vaginal Infections and High-Risk Human Papillomavirus Types in Female Sex Workers in Spain

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
C. Rodriguez-Cerdeira ◽  
E. Sanchez-Blanco ◽  
A. Alba
Keyword(s):  
Human Papillomavirus ◽  
High Risk ◽  
Bacterial Vaginosis ◽  
Sex Workers ◽  
Trichomonas Vaginalis ◽  
Female Sex Workers ◽  
Vaginal Microbiota ◽  
Transmitted Infection ◽  
Female Sex ◽  
Associated Lesions

Background. Infection with and persistence of high-risk human papillomavirus (HR-HPV) are the strongest risk factors for cervical cancer. In addition, other genital microorganisms may also be involved in the progression of HPV-associated lesions. Objetive. To evaluate the association of the vaginal microbiota (Candida spp., Trichomonas vaginalis, and bacterial vaginosis) with HR-HPV infection in Spanish female sex workers (FSWs). Methods. This cross-sectional study involved 208 (FSWs; age, 18–49 years) who visited a sexually transmitted infection (STI) information and prevention center (SERGAS) between January 2010 and December 2011. Face-to-face interviews were carried out. Cervical and vaginal samples were examined for human papillomavirus (HPV), Trichomonas vaginalis, Candida spp., and microorganisms related to bacterial vaginosis (BV). Results. HR-HPV was found to be significantly associated with BV in FSWs with positive results for HPV16-related types (31, 33, 35, and 52). T. vaginalis was isolated in FSWs with the following HR-HPVs: 18, 45, 66, and 68. Candida spp. were isolated only in FSWs with HPV 18-positive infection. Conclusion. We demonstrate a significant prevalence of HR-HPVs in FSWs with disturbances in the vaginal microbiota.

scholarly journals Gambaran Hasil Pemeriksaan Sitologi Serviks Wanita Pekerja Seksual Tidak Langsung pada Hotspot Maredan Kecamatan Tenayan Raya Pekanbaru

2017 ◽  
Vol 10 (1) ◽  
pp. 54
Author(s):  
Wiwit Ade ◽  
Sindy Oktaviani ◽  
Amru Sofian
Keyword(s):  
Cervical Cancer ◽  
Bacterial Vaginosis ◽  
Cause Of Death ◽  
Sex Workers ◽  
Trichomonas Vaginalis ◽  
Female Sex Workers ◽  
Cervical Smear ◽  
Smear Examination ◽  
The World ◽  
Intraepithelial Lesion

Cervical cancer is a malignancy of the cervix that can be prevented, but the cause of death of women due to cancer.Cervical cancer is the second most frequent cancer in women in the world. Indirect female sex workers have a higherrisk of cervical cancer. The aim of this research was to figure out description of cervical smear examination in indirectfemale sex workers at hotspot Maredan Tenayan Raya Pekanbaru. Population of this experiment were all indirectfemale sex workers at hotspot Maredan Tenayan Raya Pekanbaru and samples were taken with total sampling method.The result showed that there were 44 people consist 4% diagnosed with HSIL, 25% were diagnosed with LSIL, 30%diagnosed with ASCUS and 41% with negative for intraepithelial lesion or malignancy (Bacterial vaginosis,Trichomonas vaginalis, Candidiasis presents).

scholarly journals Bacterial vaginosis. Modern view of the problem and its status in Ukraine

2021 ◽  
pp. 72-77
Author(s):  
L.V. Kalugina ◽  
T.F. Tatarchuk ◽  
I.V. Shmulian
Keyword(s):  
Bacterial Vaginosis ◽  
Trichomonas Vaginalis ◽  
Vaginal Discharge ◽  
Treatment Strategies ◽  
Empirical Therapy ◽  
Clinical Situation ◽  
Gardnerella Vaginalis ◽  
Surgical Interventions ◽  
Long Course ◽  
Clinical Conditions

Research objective: to examine the incidence of asymptomatic and recurrent bacterial vaginosis (BV) in Ukrainian women and to evaluate diagnostic and treatment strategies for the disease control. Materials and methods. This study lasted from January to March 2021 and included 277 doctors of women's clinics, gynecological hospitals and oncology centers from all regions of Ukraine. Information was provided on 12 896 patients between of 18 and 59 ages with BV. Results. Analysis of data from 12 896 questionnaires allowed us to determine that women from 18 to 35 years of age (62.6%) were the most frequently consulted about BV. Only 58.72% patients with BV reported about abnormal vaginal discharge as the reason for visit, while 41.24% of the respondents reported other reasons. Questionnaire analysis of patients with vaginal discharge revealed scant symptoms of the disease: only 62.67% complained about the change of discharge character; 38.49% and 36.35% of examinees pointed to the vaginal itching and unpleasant odor, respectively; 19.89% of patients were troubled by dysuric symptoms and 15.10% of patients mentioned dyspareunia. In the list of submitted questionnaires, 59.92% of patients indicated an additional examination to identify the causes of vaginitis by the PCR method (urogenital scraping). According to its results, Gardnerella vaginalis was detected in diagnostically significant concentrations in 71.49% of patients, Atopobium vaginae was found in 11.32% of cases, Mobiluncus spp. was detected in 19.96% of patients and Trichomonas vaginalis was found in 13.12% of patients. Candida colonization was diagnosed in 62.07%, with Candida albicans in 48,52% cases and non-albicans forms in 13,55% of patients.In the treatment of BV priority was given to the vaginal forms of the most compliant therapy regimens: 2 times a day for 3 days or once a day for 7 days, depending on the clinical situation. Some patients opted for a long course of treatment for recurrent infections, choosing the combination metronidazole 750 mg / miconazole 200 mg 1 suppository once a day for 5 days for 12 months.Conclusion. Diagnosis of BV in Ukraine continues to be based on clinical conditions and requires a unified algorithm that will be based on current clinical guidelines and dictated by national protocols for management. High mycotic colonization (62,07%) in BV makes it expedient to use combined agents (metronidazole 750 mg / miconazole 200 mg tioconazole/tinidazole) both as etiotropic and empirical therapy and especially if there are clinical conditions that may can cause BV (before surgical interventions, after antibiotic therapy, in endocrine pathology, etc.).

scholarly journals 1354. Antibiotic Resistance and Coinfections Among Women with Sexually Transmitted Infections

2021 ◽  
Vol 8 (Supplement_1) ◽  
pp. S764-S764
Author(s):  
Brittany L Carpenter ◽  
Jacqueline D Peacock ◽  
Kyle Dubiak ◽  
Heather Fecteau ◽  
Robert Carlson
Keyword(s):  
Antibiotic Resistance ◽  
Bacterial Vaginosis ◽  
Sexually Transmitted Infections ◽  
Trichomonas Vaginalis ◽  
Resistance Testing ◽  
Lactobacillus Species ◽  
Herpes Simplex Virus 1 ◽  
Aerobic Vaginitis ◽  
Sexually Transmitted ◽  
Panel Testing

Abstract Background Sexually transmitted infections (STIs) represent a growing epidemic, particularly among America’s youth. Traditional single or dual organism STI testing is limited in its utility compared to PCR panel-based vaginitis testing. PCR panel testing can identify up to 99% of vaginitis associated organisms, while simultaneously providing information about antibiotic resistance. Methods We analyzed 10,011 vaginosis panel cases released between April 2020 and May 2021. The PCR-based vaginosis panel consists of organisms associated with bacterial vaginosis, aerobic vaginitis, yeast infections, STIs, and Lactobacillus species. This panel simultaneously detects evidence of antibiotic resistance for nine classes of drugs. Results Of 9405 cases from vaginal swabs, 618 (6.8%) were positive for at least one STI including Chlamydia trachomatis (CT), Haemophilus ducreyi, Herpes Simplex Virus 1 or 2 (HSV2), Neisseria gonorrhoeae (NG), and/or Trichomonas vaginalis. Of 603 urine samples, 7.6% were positive for at least one STI and represented a younger population. Patients younger than age 25 (33% of the cohort) were disproportionately affected by STIs, consistent with CDC findings. About 50% of all positive STI cases were in patients under 25. Evidence of bacterial vaginosis was also present in 89% of CT and NG cases, and 75% of HSV2 cases. Strikingly, we found the presence of an antibiotic resistant marker(s) to first line treatment in 76.2% of CT and 19.3% of NG cases. Conclusion Our data illustrates the advantages of utilizing a PCR-panel approach to STI detection over a targeted approach for individual organisms. Coinfections with bacterial vaginosis were common and if left unidentified, patients may receive incomplete treatment. Additionally, our data suggests that antibiotic resistance testing is imperative for effective treatment planning and antibiotic stewardship in suspected STI cases. Disclosures Brittany L. Carpenter, PhD, NxGen MDx (Employee) Jacqueline D. Peacock, PhD, MB(ASCP)CM, NxGen MDx (Employee) Kyle Dubiak, PhD, NxGen MDx (Employee) Heather Fecteau, MS, LCGC, NxGen MDx (Employee) Robert Carlson, MD, FCAP, NxGen MDx (Employee)

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