scholarly journals Virologic response of adolescents living with perinatally acquired HIV receiving antiretroviral therapy in the period of early adolescence (10–14 years) in South Africa

AIDS ◽  
2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Patience Nyakato ◽  
Michael Schomaker ◽  
Nosisa Sipambo ◽  
Karl-Günter Technau ◽  
Geoffrey Fatti ◽  
...  
Keyword(s):  
South Africa ◽  
Antiretroviral Therapy ◽  
Early Adolescence ◽  
Virologic Response ◽  
Perinatally Acquired

scholarly journals Pregnancy and Virologic Response to Antiretroviral Therapy in South Africa

PLoS ONE ◽  
2011 ◽  
Vol 6 (8) ◽  
pp. e22778 ◽  
Author(s):  
Daniel Westreich ◽  
Stephen R. Cole ◽  
Shashi Nagar ◽  
Mhairi Maskew ◽  
Charles van der Horst ◽  
...  
Keyword(s):  
South Africa ◽  
Antiretroviral Therapy ◽  
Virologic Response

scholarly journals The effect of eligibility for antiretroviral therapy on body mass index and blood pressure in KwaZulu-Natal, South Africa

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Aditi Kuber ◽  
Anna Reuter ◽  
Pascal Geldsetzer ◽  
Natsayi Chimbindi ◽  
Mosa Moshabela ◽  
...  
Keyword(s):  
South Africa ◽  
Blood Pressure ◽  
Body Mass Index ◽  
Antiretroviral Therapy ◽  
Body Mass ◽  
Treatment Guidelines ◽  
Causal Effect ◽  
Regression Discontinuity Design ◽  
National Treatment ◽  
Kwazulu Natal

AbstractWe use a regression discontinuity design to estimate the causal effect of antiretroviral therapy (ART) eligibility according to national treatment guidelines of South Africa on two risk factors for cardiovascular disease, body mass index (BMI) and blood pressure. We combine survey data collected in 2010 in KwaZulu-Natal, South Africa, with clinical data on ART. We find that early ART eligibility significantly reduces systolic and diastolic blood pressure. We do not find any significant effects on BMI. The effect on blood pressure can be detected up to three years after becoming eligible for ART.

scholarly journals Sociodemographic and lifestyle correlates of exclusive breastfeeding practices among mothers on antiretroviral therapy in the Eastern Cape, South Africa

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Daniel Ter Goon ◽  
Anthony Idowu Ajayi ◽  
Oladele Vincent Adeniyi
Keyword(s):  
South Africa ◽  
Antiretroviral Therapy ◽  
Exclusive Breastfeeding ◽  
Hiv Transmission ◽  
Cross Sectional Study ◽  
Sub Saharan Africa ◽  
Eastern Cape ◽  
Cross Sectional ◽  
Factors Associated ◽  
Breastfeeding Practice

Abstract Background Exclusive breastfeeding (EBF) is associated with a reduction of postnatal HIV transmission and optimal infant growth. Given that the factors influencing exclusive breastfeeding are multi-factorial and context-specific, we examined the prevalence and factors associated with exclusive breastfeeding practice in the first 6 months among mothers on antiretroviral therapy in the Eastern Cape, South Africa. Methods This was a cross-sectional study conducted between January to May 2018, on 469 parturient women enlisted in the prevention of mother-to-child HIV transmission cohort study in the Eastern Cape. Mothers were asked to recall whether they breastfed their infant exclusively with breast milk from birth and if so, to state how long they did. We collected relevant sociodemographic, lifestyle, and maternal information by interview. Bivariate and multivariable logistic regression analyses were fitted to determine the sociodemographic and lifestyle factors associated with exclusive breastfeeding practice. Results The prevalence of six-month exclusive breastfeeding, measured since birth, was 32.0%. E Exclusive breastfeeding’s prevalence was significantly higher among married women (36.8%), unemployed women (36.6%), non-smokers (32.7%), and those who never drank alcohol (37.0%). Unemployed women (adjusted odds ratio [AOR] 1.66, 95% Confidence Interval [CI] 1.08–2.56) and those with grade 12 or less level of education (AOR 2.76, 95% CI 1.02–7.49) had a higher likelihood of practising EBF for 6 months since birth while mothers who consumed alcohol (AOR 0.54, 95% CI 0.34–0.85) were less likely to practice EBF for 6 months. Conclusions The prevalence of six-month exclusive breastfeeding in the study, although comparable with sub-Saharan Africa and worldwide prevalence, remains suboptimal. Advocacy campaigns on EBF must target alcohol cessation and the creation of a favourable workplace environment for lactating mothers.

scholarly journals Cervical cancer risk and impact of Pap-based screening in HIV-positive women on antiretroviral therapy in Johannesburg, South Africa

2017 ◽  
Vol 141 (3) ◽  
pp. 488-496 ◽  
Author(s):  
Eliane Rohner ◽  
Mazvita Sengayi ◽  
Bridgette Goeieman ◽  
Pamela Michelow ◽  
Cynthia Firnhaber ◽  
...  
Keyword(s):  
South Africa ◽  
Cervical Cancer ◽  
Antiretroviral Therapy ◽  
Cancer Risk ◽  
Hiv Positive ◽  
Cervical Cancer Risk ◽  
Hiv Positive Women

scholarly journals Convergence of Mortality Rates among Patients on Antiretroviral Therapy in South Africa and North America

PLoS Medicine ◽  
2014 ◽  
Vol 11 (9) ◽  
pp. e1001719 ◽  
Author(s):  
Agnes Binagwaho ◽  
Cameron T. Nutt ◽  
Placidie Mugwaneza ◽  
Claire M. Wagner ◽  
Sabin Nsanzimana
Keyword(s):  
South Africa ◽  
Antiretroviral Therapy ◽  
North America ◽  
Mortality Rates

Lipodystrophy and reversal of facial lipoatrophy in perinatally HIV-infected children and adolescents after discontinuation of stavudine

2012 ◽  
Vol 23 (7) ◽  
pp. 497-501 ◽  
Author(s):  
N Sawawiboon ◽  
O Wittawatmongkol ◽  
W Phongsamart ◽  
W Prasitsuebsai ◽  
K Lapphra ◽  
...  
Keyword(s):  
Multivariate Analysis ◽  
Antiretroviral Therapy ◽  
Children And Adolescents ◽  
Median Duration ◽  
Early Adolescence ◽  
Noticeable Improvement ◽  
Facial Lipoatrophy

Lipodystrophy (LD) was evaluated in 205 children receiving antiretroviral therapy by a single investigator: 51 (24.9%) had LD; 46 peripheral lipoatrophy, three central lipohypertrophy and two combined type. All cases of peripheral and combined LD also had facial lipoatrophy. Serial photographs were provided by the families to confirm the severity of facial lipoatrophy. Forty-six (95.8%) children with peripheral or combined LD, and 75 (48.7%) without LD were exposed to stavudine (d4T) for a median duration of 45.9 versus 26.4 months (P = 0.005). In multivariate analysis, exposure to d4T for more than three months was the only factor associated with peripheral or combined LD (P < 0.001). Noticeable improvement of facial lipoatrophy was found in 11/48 (22.9%) children after a mean duration of 45.6 months following d4T discontinuation, mostly occurring during early adolescence.

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