scholarly journals Distinct antibody profiles in HLA-B*57 + , HLA-B*57 - HIV controllers and chronic progressors

AIDS ◽  
2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Jéromine Klingler ◽  
Nicodème Paul ◽  
Géraldine Laumond ◽  
Sylvie Schmidt ◽  
Luzia M. Mayr ◽  
...  
2020 ◽  
Vol 222 (11) ◽  
pp. 1837-1842 ◽  
Author(s):  
Nikolaus Jilg ◽  
Pilar Garcia-Broncano ◽  
Michael Peluso ◽  
Florencia P Segal ◽  
Ronald J Bosch ◽  
...  

Abstract AIDS Clinical Trials Group study A5308 found reduced T-cell activation and exhaustion in human immunodeficiency virus (HIV) controllers start antiretroviral therapy (ART). We further assessed HIV-specific T-cell responses and post-ART viral loads. Before ART, the 31% of participants with persistently undetectable viremia had more robust HIV-specific T-cell responses. During ART, significant decreases were observed in a broad range of T-cell responses. Eight controllers in A5308 and the Study of the Consequences of the Protease Inhibitor Era (SCOPE) cohort showed no viremia above the level of quantification in the first 12 weeks after ART discontinuation. ART significantly reduced HIV-specific T-cell responses in HIV controllers but did not adversely affect controller status after ART discontinuation.


2021 ◽  
Vol 37 ◽  
pp. 100963
Author(s):  
Léo Plaçais ◽  
Faroudy Boufassa ◽  
Camille Lécuroux ◽  
Elise Gardiennet ◽  
Véronique Avettand-Fenoel ◽  
...  

Cell Reports ◽  
2021 ◽  
Vol 35 (8) ◽  
pp. 109167
Author(s):  
Evan D. Rossignol ◽  
Anne-Sophie Dugast ◽  
Hacheming Compere ◽  
Christopher A. Cottrell ◽  
Jeffrey Copps ◽  
...  

2011 ◽  
Vol 6 (3) ◽  
pp. 202-207 ◽  
Author(s):  
Barbara L Shacklett ◽  
April L Ferre

2016 ◽  
Vol 19 (1) ◽  
pp. 20524 ◽  
Author(s):  
Trevor A Crowell ◽  
Anuradha Ganesan ◽  
Stephen A Berry ◽  
Robert G Deiss ◽  
Brian K Agan ◽  
...  

2015 ◽  
Vol 6 ◽  
Author(s):  
TABORDA NATALIA ◽  
GONZALEZ SANDRA ◽  
ALVAREZ CRISTIAM ◽  
CORREA LUIS ◽  
MONTOYA CARLOS ◽  
...  

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