Sexually acquired HIV infections in the United States due to acute-phase HIV transmission: an update

AIDS ◽  
2009 ◽  
Vol 23 (13) ◽  
pp. 1792-1794 ◽  
Author(s):  
Vimalanand S Prabhu ◽  
Angela B Hutchinson ◽  
Paul G Farnham ◽  
Stephanie L Sansom
Keyword(s):  
United States ◽  
Acute Phase ◽  
Hiv Transmission ◽  
Hiv Infections ◽  
The United States

scholarly journals Challenges in evaluating the use of viral sequence data to identify HIV transmission networks for public health

2020 ◽  
Vol 12 (s1) ◽  
Author(s):  
Rami Kantor ◽  
John P. Fulton ◽  
Jon Steingrimsson ◽  
Vladimir Novitsky ◽  
Mark Howison ◽  
...  
Keyword(s):  
Public Health ◽  
United States ◽  
Hiv Transmission ◽  
Sequence Data ◽  
The United States ◽  
Viral Sequence ◽  
Transmission Networks ◽  
New Methods ◽  
Hiv Epidemic ◽  
The World

AbstractGreat efforts are devoted to end the HIV epidemic as it continues to have profound public health consequences in the United States and throughout the world, and new interventions and strategies are continuously needed. The use of HIV sequence data to infer transmission networks holds much promise to direct public heath interventions where they are most needed. As these new methods are being implemented, evaluating their benefits is essential. In this paper, we recognize challenges associated with such evaluation, and make the case that overcoming these challenges is key to the use of HIV sequence data in routine public health actions to disrupt HIV transmission networks.

Aflatoxin B1: Its Role in the Etiology of Reye's Syndrome

PEDIATRICS ◽  
1979 ◽  
Vol 64 (1) ◽  
pp. 71-75 ◽  
Author(s):  
Nell J. Ryan ◽  
Gwendolyn R. Hogan ◽  
A. Wallace Hayes ◽  
Peter D. Unger ◽  
Mohamed V. Siraj
Keyword(s):  
United States ◽  
Acute Phase ◽  
Aflatoxin B1 ◽  
Case Reports ◽  
The United States ◽  
Reye's Syndrome ◽  
Autopsy Specimens

Seven cases of Reye's syndrome in which aflatoxin B1 was isolated from the blood or liver or both are presented. In two cases aflatoxin B1 was found in the blood during the acute phase of the disease; a finding not previously reported. In six cases aflatoxin B1 was recovered from autopsy specimens of liver. A number of case reports linking aflatoxin B1 to Reye's syndrome have appeared in the literature but until now only one case has been reported from the United States. Aflatoxin B1 and its possible role in the etiology of Reye's syndrome is discussed. It is concluded that Reye's syndrome is the result of multiple interrelated factors.

scholarly journals Implementation of a Rapid Entry Program Decreases Time to Viral Suppression Among Vulnerable Persons Living With HIV in the Southern United States

2018 ◽  
Vol 5 (6) ◽  
Author(s):  
Jonathan Colasanti ◽  
Jeri Sumitani ◽  
C Christina Mehta ◽  
Yiran Zhang ◽  
Minh Ly Nguyen ◽  
...  
Keyword(s):  
United States ◽  
Viral Suppression ◽  
Hiv Transmission ◽  
Positive Impact ◽  
Population Level ◽  
The United States ◽  
Clinic Visit ◽  
Art Initiation ◽  
Persons Living With Hiv ◽  
Sex With Men

Abstract Background Rapid entry programs (REPs) improve time to antiretroviral therapy (ART) initiation (TAI) and time to viral suppression (TVS). We assessed the feasibility and effectiveness of a REP in a large HIV clinic in Atlanta, Georgia, serving a predominately un- or underinsured population. Methods The Rapid Entry and ART in Clinic for HIV (REACH) program was implemented on May 16, 2016. We performed a retrospective cohort study with the main independent variable being period of enrollment: January 1, 2016, through May 15, 2016 (pre-REACH); May 16, 2016, through July 31, 2016 (post-REACH). Included individuals were HIV-infected and new to the clinic with detectable HIV-1 RNA. Six-month follow-up data were collected for each participant. Survival analyses were conducted for TVS. Logistic and linear regression analyses were used to evaluate secondary outcomes: attendance at first clinic visit, viral suppression, TAI, and time to first attended provider visit. Results There were 117 pre-REACH and 90 post-REACH individuals. Median age (interquartile range [IQR]) was 35 (25–45) years, 80% were male, 91% black, 60% men who have sex with men, 57% uninsured, and 44% active substance users. TVS decreased from 77 (62–96) to 57 (41–70) days (P < .0022). Time to first attended provider visit decreased from 17 to 5 days, and TAI from 21 to 7 days (P < .0001), each remaining significant in adjusted models. Conclusions This is the largest rapid entry cohort described in the United States and suggests that rapid entry is feasible and could have a positive impact on HIV transmission at the population level.

scholarly journals HIV Transmission Dynamics Among Foreign-Born Persons in the United States

2017 ◽  
Vol 76 (5) ◽  
pp. 445-452 ◽  
Author(s):  
Eduardo E. Valverde ◽  
Alexandra M. Oster ◽  
Songli Xu ◽  
Joel O. Wertheim ◽  
Angela L. Hernandez
Keyword(s):  
United States ◽  
Hiv Transmission ◽  
The United States ◽  
Transmission Dynamics ◽  
Foreign Born

scholarly journals Association Between HIV-Related Tweets and HIV Incidence in the United States: Infodemiology Study

10.2196/17196 ◽  
2020 ◽  
Vol 22 (6) ◽  
pp. e17196 ◽  
Author(s):  
Robin Stevens ◽  
Stephen Bonett ◽  
Jacqueline Bannon ◽  
Deepti Chittamuru ◽  
Barry Slaff ◽  
...  
Keyword(s):  
United States ◽  
Social Media ◽  
Hiv Infection ◽  
Language Processing ◽  
Hiv Risk ◽  
Intraclass Correlation ◽  
Hiv Infections ◽  
The United States ◽  
Infection Rates ◽  
Age Range

Background Adolescents and young adults in the age range of 13-24 years are at the highest risk of developing HIV infections. As social media platforms are extremely popular among youths, researchers can utilize these platforms to curb the HIV epidemic by investigating the associations between the discourses on HIV infections and the epidemiological data of HIV infections. Objective The goal of this study was to examine how Twitter activity among young men is related to the incidence of HIV infection in the population. Methods We used integrated human-computer techniques to characterize the HIV-related tweets by male adolescents and young male adults (age range: 13-24 years). We identified tweets related to HIV risk and prevention by using natural language processing (NLP). Our NLP algorithm identified 89.1% (2243/2517) relevant tweets, which were manually coded by expert coders. We coded 1577 HIV-prevention tweets and 17.5% (940/5372) of general sex-related tweets (including emojis, gifs, and images), and we achieved reliability with intraclass correlation at 0.80 or higher on key constructs. Bivariate and multivariate analyses were performed to identify the spatial patterns in posting HIV-related tweets as well as the relationships between the tweets and local HIV infection rates. Results We analyzed 2517 tweets that were identified as relevant to HIV risk and prevention tags; these tweets were geolocated in 109 counties throughout the United States. After adjusting for region, HIV prevalence, and social disadvantage index, our findings indicated that every 100-tweet increase in HIV-specific tweets per capita from noninstitutional accounts was associated with a multiplicative effect of 0.97 (95% CI [0.94-1.00]; P=.04) on the incidence of HIV infections in the following year in a given county. Conclusions Twitter may serve as a proxy of public behavior related to HIV infections, and the association between the number of HIV-related tweets and HIV infection rates further supports the use of social media for HIV disease prevention.

scholarly journals Perinatal HIV Service Coordination: Closing Gaps in the HIV Care Continuum for Pregnant Women and Eliminating Perinatal HIV Transmission in the United States

2018 ◽  
Vol 133 (5) ◽  
pp. 532-542
Author(s):  
Mary-Margaret Andrews ◽  
Deborah S. Storm ◽  
Carolyn K. Burr ◽  
Erika Aaron ◽  
Mary Jo Hoyt ◽  
...  
Keyword(s):  
United States ◽  
Hiv Transmission ◽  
The United States ◽  
Comprehensive Care ◽  
Hiv Care ◽  
Service Coordination ◽  
Hiv Care Continuum ◽  
Care Continuum ◽  
Perinatal Hiv ◽  
Childbearing Women

Eliminating perinatal transmission of HIV and improving the care of childbearing women living with HIV in the United States require public health and clinical leadership. The Comprehensive Care Workgroup of the Elimination of Perinatal HIV Transmission Stakeholders Group, sponsored by the Centers for Disease Control and Prevention, developed a concept of perinatal HIV service coordination (PHSC) and identified 6 core functions through (1) semistructured exploratory interviews with contacts in 11 state or city health departments from April 2011 through February 2012, (2) literature review and summary of data on gaps in services and outcomes, and (3) group meetings from August 2010 through June 2017. We discuss leadership strategies for implementing the core functions of PHSC: strategic planning, access to services, real-time case finding, care coordination, comprehensive care, and data and case reviews. PHSC provides a systematic approach to optimize services and close gaps in perinatal HIV prevention and the HIV care continuum for childbearing women that can be individualized for jurisdictions with varying needs.

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