scholarly journals The ferrier lecture on problems connected with the principle of humoral transmission of nervous impulses

Mr. President, Ladies and Gentlemen,—I am deeply appreciative of the honour, which has been done me by the President and Council of the Royal Society, in inviting me to deliver here, in this ancient and famous institution, a lecture which commemorates the work of Sir David Ferrier; and my sense of the honour is enhanced by the thought that my predecessors, as lecturers on this Foundation, have been Sir Charles Sherrington and Professor Ariëns Kappers. Each of these lectures in memory of Sir David Ferrier is to deal with some subject related to the structure or function of the nervous system. Within recent years investigations in this field have dealt not only with the course of the specific nervous functions but, in an ever-increasing degree, with the analysis of nervous action into its fundamental factors, and especially those of a chemical nature. Having been mainly interested in these lines of development, and assuming that you have chosen the lecturer with a view to his own particular field of research, I have thought it proper that I should endeavour to deal with problems connected with the principle of the humoral transmission of nervous impulses.

1849 ◽  
Vol 139 ◽  
pp. 47-48

Since the communication above referred to was presented to the Royal Society, I have made a very minute dissection in alcohol of the whole nervous system of the young heifer’s heart. The distribution of the ganglia and nerves over the entire surface of the heart, and the relations of these structures to the blood-vessels and muscular substance, are far more fully displayed in these preparations than in any of my former dissections. On the anterior surface, there are distinctly visible to the naked eye ninety ganglia or ganglionic enlargements on the nerves, which pass obliquely across the arteries and the muscular fibres of the ventricles from their base to the apex. These ganglionic enlargements are observed on the nerves, not only where they are crossing the arteries, but where they are ramifying on the muscular substance without the blood-vessels. On the posterior surface, the principal branches of the coronary arteries plunge into the muscular substance of the heart near the base, and many nerves with ganglia accompany them throughout the walls to the lining membrane and columnse carneæ. From the sudden disappearance of the chief branches of the coronary arteries on the posterior surface, the nervous structure distributed over a consider­ able portion of the left ventricle is completely isolated from the blood-vessels, and on these, numerous ganglionic enlargements are likewise observed, but smaller in size than the chains of ganglia formed over the blood-vessels on the anterior surface of the heart. In the accompanying beautiful drawings, Mr. West has depicted with the greatest accuracy and minuteness the whole nervous structures demon­strable in these preparations on the surface of the heart. But the ganglia and nerves represented in these drawings constitute only a small portion of the nervous system of the heart, numerous ganglia being formed in the walls of the heart which no artist can represent. It can be clearly demonstrated that every artery distributed throughout the walls of the Uterus and Heart, and every muscular fasciculus of these organs, is supplied with nerves upon which ganglia are formed.


1823 ◽  
Vol 9 (2) ◽  
pp. 365-379 ◽  
Author(s):  
H. Dewar

The communication received from Dr Dyce chiefly consists of a description of a singular affection of the nervous system, and mental powers, to which a girl of sixteen was subject immediately before puberty, and which disappeared when that state was fully established. It exemplifies the powerful influence of the state of the uterus on the mental faculties; but its chief value arises from some curious relations which it presents to the phenomena of mind, and which claim the attention of the practical metaphysician. The mental symptoms of this affection are among the number of those which are considered as uncommonly difficult of explanation. It is a case of mental disease, attended with some advantageous manifestations of the intellectual powers; and these manifestations disappearing in the same individual in the healthy state.


2001 ◽  
Vol 82 (5) ◽  
pp. 321-325
Author(s):  
G. I. Poletaev

The mechanism of nerve-to-muscle transmission, as well as the trophic influence of the nervous system on effector organs, have always been in the focus of attention of scientists of the Kazan physiological school. Suffice it to recall the famous physiologist A.F. Samoilov, who in 1924 for the first time established the chemical nature of neuromuscular transmission.


1864 ◽  
Vol s2-4 (15) ◽  
pp. 241-246
Author(s):  
WILLIAM HENDRY

The author stated that four years since, in attempting to substitute fusion by the blowpipe for cement, in fixing their glass covers to slides, he noticed masses of crystals produced in the covers after the treatment, and believing them to be unkown, he named them after himself. To obtain the crytals he heats a thin glass cover on a piece of mica, over a spirit-lamp, holding both with forceps; then quickly turning them to the side of the flame, applies a blowpipe, withdrawing the cover to the apex of the flame for a few moments. An examination with a 1 or ½inch objective will then show the crystals. Similar results were ottseryed in a thin glass slide, after a similar treatment, when examined with a 1/12th objective. Specimens were sent with the paper, and the author suggests that it would be desirable to ascertain the chemical nature of the crystals, whether a silicate of lead or soda.


Author(s):  
Michael J. Aminoff

Charles Bell and his wife both had ecclesiastical backgrounds. Like many contemporary scientists, Bell was a creationist who believed in intelligent design. He not only published notes and supplementary dissertations to William Paley’s Natural Theology but also wrote a treatise on Animal Mechanics and a Bridgewater Treatise on The Hand. Natural theology had begun to decline in importance in the 1830s, however, seeming increasingly tired and dated in an era of change. Bell’s anatomical teaching—framed on the concept of intelligent design—was thus overshadowed by the concepts of Buffon, Geoffroy, Lamarck, Robert Grant, and Charles Darwin and by the teachings of younger, more modern professors. Nevertheless, national honors came his way—the Gold (Royal) Medal of the Royal Society for his work on the nervous system and a knighthood in 1831.


1832 ◽  
Vol 122 ◽  
pp. 383-398 ◽  

In this paper it is proposed to describe the development and arrangement of the nerves, and the changes which they undergo, in the Sphinx Ligustri , Linn., during the last stage of the larva, and the earlier stages of the pupa state. The labours of that industrious naturalist Heroldt have already shown us, to a certain extent, in what manner similar changes occur in the Papilio Brassincæ Linn.; and therefore the author of the present essay would not have ventured to trespass upon the attention of the Royal Society, were it not that these changes are capable of more minute explanation than those which take place with such rapidity in the P. brassicæ . But the Sphinx ligustri , Linn., remaining as it does for several months in an apparently torpid condition, between its larva and perfect state, allows us an opportunity of more deliberately observing in what manner the changes are effected; while the superior bulk of the insect enables us to trace them with greater precision.


When the flattering invitation to deliver this year’s Croonian Lecture before your far-farmed Royal Society reached me, I first of all felt considerable hesitation as to whether I should be able to discharges so honourable a task. The very choice, out of the field of my investigations, of a subject which should be suitable for lecturing to you about, presented a very real difficulty. During the past 20 years I have been working principally in three departments of scientific research— the Nervous System of Vertebrata and Invertebrata, Physical Anthropology in Sweden , and the Spermia of Animals of all Orders .


1843 ◽  
Vol 133 ◽  
pp. 243-302 ◽  

The increasing importance that is daily attached to the study of the comparative anatomy of the Invertebrata, and the interest with which every microscopic exami­nation of structure is now regarded, as assisting to elucidate the great problems of life in the higher animals, have encouraged me through several years to prosecute a series of investigations, in the articulated classes, on two of the most important portions of the body,—the nervous and circulatory systems. These investigations have afforded me, from time to time, some interesting results, part of which, on one of these structures, I have already had the honour of communicating to the Royal Society. I now propose to communicate the results of my examinations of both these structures, and to illustrate their development, and the relations which they bear to each other, in some of the principal classes, commencing, in the present paper, with the Myriapoda and Arachnida. The objects to which my attention has been directed in this paper are three:— First , the minute anatomy of the nervous system in the Myriapoda and Macrourous Arachnida, more especially with regard to the structure of the cord and its ganglia, and the means which these afford us of explaining the physiology of the nervous system, and the phenomena of the reflected movements in articulated animals. Secondly , to demonstrate the existence of a complete system of circulatory vessels in the Myriapoda and Arachnida. Thirdly , to show the identity of the laws that regulate the development of the nervous and circulatory systems in these Articulata, and their dependence on the changes which take place in the muscular and tegu­mentary structures of the body, as I formerly showed in regard to the changes in the nervous system of insects.


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