Comments on: “A comprehensive repertoire of tRNA-derived fragments in prostate cancer”
Keyword(s):
Rna Seq
◽
We evaluated the deep-sequencing (RNA-seq) data from human prostate tissue that were reported in [1] and the tRNA-derived fragments described in the original analysis. Our study of the same RNA-seq datasets reveals a considerably different pool of tRNA fragments, many of them with higher abundances than the fragments reported in [1]. We also evaluated the q-PCR approach proposed in [1]. As the approach lacks 5’-endpoint specificity, it will not estimate correctly the abundance of many of the tRFs that are present in the sampled RNA populations from human prostate tissue.
Keyword(s):
2019 ◽
Vol 11
◽
pp. 175628721985230
◽
2005 ◽
Vol 515
(1-3)
◽
pp. 20-27
◽
Keyword(s):
Keyword(s):
2003 ◽
Vol 23
(9)
◽
pp. 1183-1188
◽
Keyword(s):