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2022 ◽  
Vol 11 (4) ◽  
pp. 511-517
Author(s):  
P Sean Morris*

While the debate on intellectual property and international investment law is relatively young, the role of historical cases will be important in offering some interpretative analysis. Due to the niche nature of both areas of law, where, often times, the legal luminaries found in both areas often speak past each other, in an earlier issue of this journal I offered an interpretative history of Chorzów Factory as an example of early case law by an international court illustrating the origins of the ISDS involving intellectual property. As with any interpretation, there are bound to be opposing views or explicit endorsement, but whatever the merits, that interpretative history has initiated a debate in the pages of this journal. That debate is in part, a response to my original analysis, to which I offer a response. This response is to endorse the fact that additional information has come forward that will enrich the debate on Chorzów Factory and its connection to intellectual property. Moreover, this response argues that the reply misses the point regarding the formal connection of international law to intellectual property in ISDS, a connection that I attempted to demonstrate through the example of the Chorzów Factory case – where a legal fight in the 1920s over nitrate, other chemical production and ownership still continue to be of relevance to international law.


2021 ◽  
Vol 28 (3-4) ◽  
pp. 125-152
Author(s):  
Miriam Feldmann Kaye

Abstract This paper explores the post-metaphysical theology of Richard Kearney (1954–) from a Jewish theological perspective. It seeks to provide an original analysis of his project “anatheism,” considering the prominence of Jewish texts in the development of the concept of anatheism. Rooted in deconstructionist and Continental philosophical discourses, Jewish hermeneutics also plays a central role in anatheism. This discursive intersection has received scarce scholarly attention to date. Biblical and other texts which he interprets, include the rabbinic exegesis of Rashi and of modern Jewish hermeneutical philosophy notably of Martin Buber, Franz Rosenzweig, and Emmanuel Levinas. I analyse elements of Kearney’s interpretation primarily of the “Burning Bush” biblical narrative as a test case for anatheistic reading of Jewish texts as they appear in one particular text “I Am Who May Be” in The God Who May Be: A Hermeneutics of Religion (2001). Kearney’s textual reading of the Burning Bush offers an unusual example of a Christian engagement with Jewish interpretations of the biblical parable as well as of Levinas, Derrida, and others. Kearney’s effort highlights an approach of a mutual search for ways of interpreting texts not “of” the other, but “with” the other, in a mutual engagement of post-metaphysical theology. More broadly, this examination offers an important contribution to the developing field of post-metaphysical theology in the Jewish and Christian traditions, ultimately posing questions as to how and whether elements of Jewish scriptural interpretative techniques might or can imbue contemporary Christian post-metaphysical theologies. Conversely, the question can be asked as to what a Jewish version of anatheism might look like. This examination presents a test case for possibilities of reading and learning from discourses across different religions.


Politeja ◽  
2021 ◽  
Vol 18 (5(74)) ◽  
pp. 177-192
Author(s):  
Ilona Dardzińska

The Symbolism of Urban Space Versus the Symbol of Public Space The article presents an original analysis of the symbolism of urban space and types of symbols complementing public space. It describes the symbolism of a space, what creates it, how it can be interpreted and what role it played in the past and now. Extremely interesting examples of symbolic structures in Poland and other European countries are presented. The features and functions of the symbol in the public space are distinguished and its meaning for the recipient is indicated.


2021 ◽  
Vol 2086 (1) ◽  
pp. 012141
Author(s):  
A Gavrilovich ◽  
D Sych ◽  
Y Kurochkin

Abstract Passive generation is a sophisticated way of state preparation in quantum key distribution (QKD) systems which is designed to exploit some internal physical process as a source of randomness. It can be profitable in a wide range of scenarios. However, the original analysis of the passive scheme implies an ideal interference which is almost impossible to assure in practice, therefore utilizing such method potentially compromises the security of the system. Here we develop a general technique to estimate decoy-state parameters for a passive protocol with an arbitrary experimental distribution of intensity. We compare this analysis with the original method and show that the proposed technique can provide higher key generation rates.


Mathematics ◽  
2021 ◽  
Vol 9 (21) ◽  
pp. 2777
Author(s):  
Ivan Arraut ◽  
João Alexandre Lobo Marques ◽  
Sergio Gomes

The spontaneous symmetry breaking phenomena applied to Quantum Finance considers that the martingale state in the stock market corresponds to a ground (vacuum) state if we express the financial equations in the Hamiltonian form. The original analysis for this phenomena completely ignores the kinetic terms in the neighborhood of the minimal of the potential terms. This is correct in most of the cases. However, when we deal with the martingale condition, it comes out that the kinetic terms can also behave as potential terms and then reproduce a shift on the effective location of the vacuum (martingale). In this paper, we analyze the effective symmetry breaking patterns and the connected vacuum degeneracy for these special circumstances. Within the same scenario, we analyze the connection between the flow of information and the multiplicity of martingale states, providing in this way powerful tools for analyzing the dynamic of the stock markets.


2021 ◽  
Vol 8 (Supplement_1) ◽  
pp. S798-S798
Author(s):  
Anne Santerre Henriksen ◽  
Lindsay Nicolle ◽  
Anita F Das

Abstract Background In 2019, the FDA issued guidance on drug development for treatment of UTIs. To explore the impact of this guidance, we compared clinical and microbiological outcomes of the fluoroquinolones norfloxacin and ciprofloxacin and the β-lactams pivmecillinam and sulopenem for treatment of uUTIs from original publications versus recent analyses conducted in accordance with the FDA guidance. Methods The efficacy of pivmecillinam 400 mg twice daily (BID), 3 days (3d) versus norfloxacin 400 mg BID, 3d was reported in a 2002 publication. Patient-level data were used to re-analyze clinical and microbiological outcomes in the microbiological intent-to-treat population in accordance with the 2019 FDA guidance. For descriptive comparison, we present the efficacy of ciprofloxacin 250 mg BID, 3d vs sulopenem 500 mg BID, 5d in the 2020 SURE-1 trial (also conducted in accordance with FDA guidance) alongside historical efficacy data for ciprofloxacin. Results Re-analysis of data from the trial of pivmecillinam and norfloxacin showed microbiological responses for pivmecillinam and norfloxacin of 64% and 79%, respectively. Microbiological responses were higher, 75% for pivmecillinam and 91% for norfloxacin, in the original analysis. For clinical response, re-analysis showed 75% for pivmecillinam and 88% for norfloxacin, while historical data were 82% and 88%, respectively. In the SURE-1 trial, the microbiological response of patients assessed at Day 12 was 76.6% for sulopenem and 79.1% for ciprofloxacin. In a 2002 publication, bacterial eradication at 4 to 11 days after treatment was 93.7% for ciprofloxacin 250 mg, a higher response rate than that reported in SURE-1. For clinical response, rates were 78.7% for ciprofloxacin in SURE-1 and 92.7% for the historical ciprofloxacin data. Conclusion When assessed in accordance with the 2019 FDA guidance, clinical and microbiological efficacy of both fluoroquinolones and β-lactam antibiotics appears lower than has been published in the past. Healthcare providers should be aware that newer antibiotics may appear to have a lower efficacy than older antibiotics due to the application of more stringent definitions in the FDA guidance. Disclosures Anne Santerre Henriksen, MS, Advanz (Consultant)Shionogi BV (Consultant)UTILITY Therapeutics (Consultant) Lindsay Nicolle, MD, Entos (Consultant)GSK (Consultant)Iterum (Consultant)Utility Therapeutics (Consultant) Anita F. Das, PhD, Adagio Therapeutics, Inc. (Consultant)


2021 ◽  
Vol 17 (2) ◽  
Author(s):  
Kathryn Tabb

The biopsychosocial model, which was deeply influential on psychiatry following its introduction by George L. Engel in 1977, has recently made a comeback. Derek Bolton and Grant Gillett have argued that Engel’s original formulation offered a promising general framework for thinking about health and disease, but that this promise requires new empirical and philosophical tools in order to be realized. In particular, Bolton and Gillett offer an original analysis of the ontological relations between Engel’s biological, social, and psychological levels of analysis. I argue that Bolton and Gillett’s updated model, while providing an intriguing new metaphysical framework for medicine, cannot resolve some of the most vexing problems facing psychiatry, which have to do with how to prioritize different sorts of research. These problems are fundamentally ethical, rather than ontological. Without the right prudential motivation, in other words, the unification of psychiatry under a single conceptual framework seems doubtful, no matter how compelling the model. An updated biopsychosocial model should include explicit normative commitments about the aims of medicine that can give guidance about the sorts of causal connections to be prioritized as research and clinical targets.


2021 ◽  
Vol 4 ◽  
Author(s):  
Dániel Kondor ◽  
Nikola Bulatovic ◽  
József Stéger ◽  
István Csabai ◽  
Gábor Vattay

Bitcoin and Ethereum transactions present some of the largest real-world complex networks that are publicly available for study, including a detailed picture of their time evolution. As such, they have received a considerable amount of attention from the network science community along with analyses from economic and cryptographic perspectives. Among these studies, in an analysis on the early instance of the Bitcoin network, we have shown the clear presence of the preferential attachment, or the “rich-get-richer” phenomenon. Now, we revisit this question, using a recent version of the Bitcoin network that has grown almost 100-fold since our original analysis. Furthermore, we additionally carry out a comparison with Ethereum, the second most important cryptocurrency. Our results show that preferential attachment continues to be a key factor in the evolution of both the Bitcoin and Ethereum transactoin networks. To facilitate further analysis, we publish a recent version of both transaction networks, and an efficient software implementation that is able to evaluate linking statistics necessary for learn about preferential attachment on networks with several hundred million edges.


Author(s):  
Zbigniew Chojnowski

The article attempts to discuss and evaluate the book The Passion of the Tristan Myth in Modern Literature, Philosophy, and Music by Artur Żywiołek, which was published in Cracow in 2021. The reviewer starts with the legend of Tristan and Isolde, which the book explores through modernity. According to the author of the article, the book about Tristan myth combines methodologies of such fields as literary studies, musicology, history, cultural studies and philosophy in a great way. In the conclusions, the reviewer evaluates the book in a favourable light, and states that it constitutes an original analysis which will have a considerable influence on the comparative studies. 


2021 ◽  
pp. 002200272110267
Author(s):  
Robert A. Blair ◽  
Nicholas Sambanis

Beger, Morgan, and Ward (BM&W) call into question the results of our article on forecasting civil wars. They claim that our theoretically-informed model of conflict escalation under-performs more mechanical, inductive alternatives. This claim is false. BM&W’s critiques are misguided or inconsequential, and their conclusions hinge on a minor technical question regarding receiver operating characteristic (ROC) curves: should the curves be smoothed, or should empirical curves be used? BM&W assert that empirical curves should be used and all of their conclusions depend on this subjective modeling choice. We extend our original analysis to show that our theoretically-informed model performs as well as or better than more atheoretical alternatives across a range of performance metrics and robustness specifications. As in our original article, we conclude by encouraging conflict forecasters to treat the value added of theory not as an assumption, but rather as a hypothesis to test.


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