How safe is Covishield (ChAdOx1nCoV-19) vaccine? Experience from a tertiary care hospital in South India

AbstractBackgroundCOVID vaccine has been recently rolled out for Health care workers in India. Though vaccine trials and data are available, people, including HCWs, need more real-life data from their contexts to get over the vaccine hesitancy. We aimed to determine the incidence of Adverse Event Following Immunisation (AEFI) among HCWs after their first dose of ChAdOx1nCoV-19 vaccineMethodsWe conducted a cross-sectional study among 218 staff of a tertiary care hospital. We circulated a google form with informed consent on the hospital WhatsApp platform and asked them to self-report their vaccination experience.ResultsTwo thirds (69.7% (152/218), 95% CI: 63.1-75.7) had minor AEFI, and none had severe AEFI. Body ache (46.8% (102/218), 95% CI :40 – 53.6) was the most common symptom followed by headache (30.3% (66/218), 95% CI :24.2 – 36.8) and fever (22% 948/218), 95% CI :16.7 – 28.1). Most of them (39.4% (87/218) 95% CI:32.9 – 46.2) experienced symptoms within 4-24 hours after taking the vaccine while 22.3% (49/218) (95% CI: 17.1 – 28.6) experienced it after a day. Majority of the HCWs (78.9% (172/218), 95% CI: 72.8 – 84.1) were anxious before the vaccination. Younger age group and female gender were significantly associated with AEFI compared to their counterparts.ConclusionHCWs experienced minor, self-limiting AEFI with the first dose of ChAdOx1nCoV-19. The hospital reported no serious AEFI following the vaccination

Download Full-text

Knowledge, attitude and practice regarding tuberculosis among the patients attending a tertiary care hospital in Maharashtra, India: a cross sectional study

International Journal of Advances in Medicine ◽

10.18203/2349-3933.ijam20191143 ◽

2019 ◽

Vol 6 (2) ◽

pp. 371

Author(s):

Nilesh S. Sonawane ◽

Chaitanya R. Patil

Keyword(s):

Tertiary Care Hospital ◽

Tertiary Care ◽

Cross Sectional Study ◽

Common Symptom ◽

Care Hospital ◽

Sectional Study ◽

Cross Sectional ◽

Female Ratio ◽

Attitude And Practice ◽

Knowledge Attitude And Practice

Background: Tuberculosis is major public health problem especially in the low and middle income countries like India. We conducted a study to assess the knowledge, attitude and practice related to tuberculosis among the patients attending our tertiary care institute.Methods: A cross sectional study was conducted in a tertiary care hospital on the patients attending OPD of tertiary care hospital in Maharashtra. The patients with debilitating illness or bed bound patients and those diagnosed and cured of tuberculosis or were on treatment of tuberculosis were excluded from the study. A pretested and designed questionnaire was used to assess the knowledge, attitude and practice about the cause, clinical features and treatment of tuberculosis.Results: The mean age of the study subjects was 43.34±11.23 years with male: female ratio of 1.45. About 16.67% of the subjects stated that cause of TB is bacteria, 51.33% reported that cough was the most common symptom, 58.67% believed that it spreads from person to person and among the people who said it spreads 58.67% said that it can be preventable.Conclusions: About 1/5th of the study subjects expressed the cause of TB is bacteria or germs, and more than ½ believed that TB spreads from person to person. About 2/3rd of the patients felt that TB was a very serious disease; more than ½ of them expressed fear if they were diagnosed with TB but more than ½ of them also expressed rejection if they have a TB patient as a closed one.

Download Full-text

Rational and irrational use of intra-venous infusions: a cross-sectional study among patients of a tertiary care hospital

International Journal of Advances in Medicine ◽

10.18203/2349-3933.ijam20193287 ◽

2019 ◽

Vol 6 (4) ◽

pp. 1286

Author(s):

Amber G. ◽

Muhammad J. Khan ◽

Amina K. ◽

Warda G. ◽

Murtaza G. ◽

...

Keyword(s):

Tertiary Care Hospital ◽

Tertiary Care ◽

Age Groups ◽

Female Gender ◽

Cross Sectional Study ◽

Care Hospital ◽

Sectional Study ◽

Cross Sectional ◽

Adult Age ◽

Significant Difference

Background: Intravenous infusions (IV) are a rapid mean of administering drugs. Hospitals are commonplace for their use, but at the same time they have many serious potential complications. This study aims to know the justified use of intravenous infusion among patients of a tertiary care hospital and awareness about its use.Methods: It was a cross-sectional study in which 249 subjects were conveniently studied. Nil per oral, severity of dehydration, vomiting, and diarrhoea was used as confirmatory criteria for using IV Infusions. Questionnaire with verbal consent was used to collect the data. Descriptive statistical analysis was applied to analyse the data and presented as means, frequencies and percentages in the form of tables and figure.Results: Total n249 (100%) subjects, n68 (27.3%) males and n181 (72.7%) females with average age was 24.05±14.21 years participated. Among n116 (46.6%) irrational users, females n76 (30.5%) were more then males n40 (16.1) with significant difference, p= 0.018. However, no significant difference was found among other variables (age groups, profession, education, awareness and rational or irrational use of IV infusion). Majority n249, n204 (81.9%) were not aware of the IV infusion medication error and doctors were most common unjustified prescribers of IV infusion, n105 (90.5%).Conclusions: The study concluded with the more prevalent irrational IV infusion use in our setup. Doctors appeared the dominant prescriber of irrational IV infusion. This statement is astonishing and must not be overlooked. Female gender, adult age, under-grade patients and students are more exposed to irrational IV infusion.

Download Full-text

Prevalence of peripheral artery disease in diabetic patients of a tertiary care hospital

International Journal of Advances in Medicine ◽

10.18203/2349-3933.ijam20193140 ◽

2019 ◽

Vol 6 (4) ◽

pp. 1074

Author(s):

Sangeetha Meena ◽

Manikandan R. C.

Keyword(s):

Tertiary Care Hospital ◽

Tertiary Care ◽

Ankle Brachial Index ◽

Female Gender ◽

Arterial Disease ◽

Cross Sectional Study ◽

Diabetic Patients ◽

Care Hospital ◽

Cross Sectional ◽

Peripheral Arterial

Background: Peripheral Arterial disease (PAD) is a major microvascular complication of diabetic mellitus. Patients with diabetes have an increased prevalence of PAD. The Ankle branchial Index (ABI) is an easy, noninvasive and often underutilized tool for diagnosis of PAD. The aim of this study is to detect the prevalence of PAD in diabetic patients using Ankle Brachial Index (ABI). Since most of the patients with PAD are asymptomatic, routine screening for the same is necessary to avoid lower limb ulcerations and amputation.Methods: In this cross-sectional study, 200 diabetic patients attending a tertiary care hospital in the Kancheepuram district of Tamilnadu were screened for the prevalence of PAD using ABI and to find out risk factors associated with it.Results: Among the 200 diabetic patients who underwent ABI measurements using handheld Doppler, 19.5% were found to be having PAD. Most of them were symptomatic. Age more than 50 years and female gender were considered as statistically significant (P<0.05) determinants of PAD.Conclusions: PAD is relatively common in elderly diabetics. ABI measurement is a valid tool in early detection of PAD and therefore regular follow up will decrease disabilities in the diabetic population.

Download Full-text