scholarly journals High-throughput production of functional prototissues capable of producing NO for vasodilation

2021 ◽  
Author(s):  
Xiangxiang Zhang ◽  
Chao Li ◽  
Fukai Liu ◽  
Wei Mu ◽  
Yongshuo Ren ◽  
...  
Keyword(s):  
High Throughput ◽  
Cellular Communications ◽  
Order Number ◽  
Enzyme Reactions ◽  
Field Distributions ◽  
Two Component ◽  
Biomedical Field ◽  
Living Tissues ◽  
The Magnetic Field ◽  
High Throughput Manner

Bottom-up synthesis of prototissues helps us to understand the internal cellular communications in the natural tissues and their functions, as well as to improve or repair the damaged tissues. The existed prototissues are rarely used to improve the function of living tissues. We demonstrated a methodology to produce spatially programmable prototissues based on the magneto-Archimedes effect in a high-throughput manner. More than 2000 prototissues are produced once within 2 hours. Two-component and three-component spatial coded prototissues are fabricated by varying the addition giant unilamellar vesicles (GUVs) order/number, and the magnetic field distributions. Two-step and three-step signal communications in the prototissues are realized using cascade enzyme reactions. More importantly, the two-component prototissues capable of producing nitric oxide (NO) cause vasodilation of rat blood vessels in the presence of glucose and hydroxyurea. The tension force decreases 2.59 g, meanwhile the blood vessel relaxation is of 31.2%. Our works pave the path to fabricate complicated programmable prototissues, and hold great potential in tissue transplantation in the biomedical field.

Kinetic Solvent Effects in Organic Reactions

2017 ◽  
Author(s):  
Belinda Slakman ◽  
Richard West
Keyword(s):  
Solvent Effect ◽  
Reaction Kinetics ◽  
Computational Methods ◽  
High Throughput ◽  
Kinetic Modeling ◽  
Solvent Effects ◽  
Reaction Rates ◽  
Prior Work ◽  
Solvent Phase ◽  
High Throughput Manner

<div> <div> <div> <p>This article reviews prior work studying reaction kinetics in solution, with the goal of using this information to improve detailed kinetic modeling in the solvent phase. Both experimental and computational methods for calculating reaction rates in liquids are reviewed. Previous studies, which used such methods to determine solvent effects, are then analyzed based on reaction family. Many of these studies correlate kinetic solvent effect with one or more solvent parameters or properties of reacting species, but it is not always possible, and investigations are usually done on too few reactions and solvents to truly generalize. From these studies, we present suggestions on how best to use data to generalize solvent effects for many different reaction types in a high throughput manner. </p> </div> </div> </div>

A centrifuge-based stepwise chemical loading disc for the production of multiplex anisotropic metallic nanoparticles

RSC Advances ◽  
2015 ◽  
Vol 5 (3) ◽  
pp. 1846-1851 ◽  
Author(s):  
Byung Hyun Park ◽  
Ji Hyun Lee ◽  
Jae Hwan Jung ◽  
Seung Jun Oh ◽  
Doh C. Lee ◽  
...  
Keyword(s):  
High Throughput ◽  
Metallic Nanoparticles ◽  
Au Nps ◽  
High Throughput Manner ◽  
Chemical Loading

We have proposed a novel rotary microdevice in which multiplex anisotropic Au NPs could be synthesized under diverse conditions in a high-throughput manner.

High-throughput hyaluronic acid hydrogels array for cell selective adhesion screening

2021 ◽  
Author(s):  
Cong Wang ◽  
Hongye Hao ◽  
Jing Wang ◽  
Yunfan Xue ◽  
Jun-jie Huang ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Extracellular Matrix ◽  
Hyaluronic Acid ◽  
High Throughput ◽  
Biomedical Field

As a component of extracellular matrix (ECM), hyaluronic acid (HA) has plenty of applications in biomedical field such as tissue engineering. Due to its non-adhesive nature, HA requires further functional...

scholarly journals The Two Component Magnetic Field of the Galaxy

1990 ◽  
Vol 140 ◽  
pp. 54-54
Author(s):  
R.R. Andreassian ◽  
A.N. Makarov
Keyword(s):  
Magnetic Field ◽  
Magnetic Fields ◽  
Field Configuration ◽  
Radio Sources ◽  
Magnetic Field Configuration ◽  
Spiral Arms ◽  
Two Component ◽  
The Galaxy ◽  
The Magnetic Field ◽  
Spiral Arm

The present paper is devoted to a study of the magnetic field configuration of our Galaxy based on Faraday rotation measures (RM) of 185 pulsars and 802 extragalactic radio sources. RM data of pulsars located near the plane of the Galaxy are used for the study of magnetic fields in neighbouring spiral arms. For the distribution of spiral arms the well-known model of Georgelin and Georgelin (1976) is used. The calculations show (for details see Andreassian and Makarov, 1987, 1989) that in the Perseus spiral arm and the local Orion arm the magnetic fields have approximately the same directions (lo;bo) ≈ (80°;0°), while in the Sagittarius-Carina arm the magnetic field has an opposite direction.

scholarly journals Comparative Study on Planetary Magnetosphere in the Solar System

Sensors ◽  
2020 ◽  
Vol 20 (6) ◽  
pp. 1673
Author(s):  
Ching-Ming Lai ◽  
Jean-Fu Kiang
Keyword(s):  
Magnetic Field ◽  
Solar Wind ◽  
Solar System ◽  
Comparative Study ◽  
Magnetic Reconnection ◽  
Tilt Angle ◽  
Planetary Magnetosphere ◽  
Field Distributions ◽  
Mhd Simulations ◽  
The Magnetic Field

The magnetospheric responses to solar wind of Mercury, Earth, Jupiter and Uranus are compared via magnetohydrodynamic (MHD) simulations. The tilt angle of each planetary field and the polarity of solar wind are also considered. Magnetic reconnection is illustrated and explicated with the interaction between the magnetic field distributions of the solar wind and the magnetosphere.

Orientation dependence of the magnetic field distributions in large single crystals of

2006 ◽  
Vol 374-375 ◽  
pp. 225-228 ◽  
Author(s):  
W.J. Kossler ◽  
A.J. Greer ◽  
R.N. Dickes ◽  
D. Sicilia ◽  
Y. Dai
Keyword(s):  
Magnetic Field ◽  
Single Crystals ◽  
Orientation Dependence ◽  
Field Distributions ◽  
The Magnetic Field

scholarly journals Effects of Vortex Pinning on the Temperature Dependence of the Magnetic Field Distributions in Superconductors

2012 ◽  
Vol 30 ◽  
pp. 245-248
Author(s):  
W.J. Kossler ◽  
Allan J. Greer ◽  
Dale R. Harshman ◽  
C.E. Stronach ◽  
A.C. Shockley ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Temperature Dependence ◽  
Vortex Pinning ◽  
Field Distributions ◽  
The Magnetic Field

scholarly journals Rapid formation of size-controllable multicellular spheroids via 3D acoustic tweezers

Lab on a Chip ◽  
2016 ◽  
Vol 16 (14) ◽  
pp. 2636-2643 ◽  
Author(s):  
Kejie Chen ◽  
Mengxi Wu ◽  
Feng Guo ◽  
Peng Li ◽  
Chung Yu Chan ◽  
...  
Keyword(s):  
High Throughput ◽  
Potential Field ◽  
Multicellular Spheroids ◽  
Rapid Formation ◽  
Acoustic Tweezers ◽  
High Throughput Manner

A 3D acoustic tweezers platform is developed to fabricate size-controllable multicellular spheroids in a rapid and high-throughput manner, utilizing the acoustic Gor'kov potential field and microstreaming.

A hollow fiber system for simple generation of human brain organoids

2017 ◽  
Vol 9 (9) ◽  
pp. 774-781 ◽  
Author(s):  
Yujuan Zhu ◽  
Li Wang ◽  
Fangchao Yin ◽  
Yue Yu ◽  
Yaqing Wang ◽  
...  
Keyword(s):  
Stem Cell ◽  
Human Brain ◽  
High Throughput ◽  
Hollow Fiber ◽  
Cell Biology ◽  
Hollow Fibers ◽  
Stem Cell Biology ◽  
Fiber System ◽  
Novel Approach ◽  
High Throughput Manner

Here we present a novel approach to engineer hiPSC-derived brain organoids within hollow fibers in a simple and high throughput manner by integrating biomaterials with stem cell biology.

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