scholarly journals A Transparent Ultrasound Array for Real-time Optical, Ultrasound and Photoacoustic Imaging

2021 ◽  
Author(s):  
Haoyang Chen ◽  
Sumit Agrawal ◽  
Mohamed Osman ◽  
Josiah Minotto ◽  
Shubham Mirg ◽  
...  
Keyword(s):  
Real Time ◽  
Multimodal Imaging ◽  
Photoacoustic Imaging ◽  
Vascular Diseases ◽  
Ultrasound Transducer ◽  
Ultrasound Waves ◽  
Imaging Capability ◽  
Imaging Results ◽  
Potential Applications ◽  
Diagnostic Sensitivity And Specificity

Objective and Impact Statement: Simultaneous imaging of ultrasound and optical contrasts can help map structural, functional and molecular biomarkers inside living subjects with high spatial resolution. There is a need to develop a platform to facilitate this multimodal imaging capability to improve diagnostic sensitivity and specificity. Introduction: Currently, combining ultrasound, photoacoustic and optical imaging modalities is challenging due to complex arrangements, in order to co-align both optical and ultrasound waves within the same field of view, because conventional ultrasound transducer arrays are optically opaque. Methods: One elegant solution is to make the ultrasound transducer transparent to light. Here, we demonstrate a novel transparent ultrasound transducer (TUT) liner array fabricated using a transparent lithium niobate piezoelectric material for real-time multimodal imaging. Results: The TUT array consisted of 64 elements and centered at ~6 MHz frequency. We demonstrate a quad-mode ultrasound, Doppler ultrasound, photoacoustic and fluorescence imaging in real-time using the TUT array directly coupled to the tissue mimicking phantoms. Conclusion: The TUT array successfully showed a multimodal imaging capability, and has potential applications in diagnosing cancer, neuro and vascular diseases, including image-guided endoscopy and wearable imaging.

scholarly journals Double-Clad Optical Fiber-Based Multi-Contrast Noncontact Photoacoustic and Fluorescence Imaging System

Electronics ◽  
2021 ◽  
Vol 10 (23) ◽  
pp. 3008
Author(s):  
Jun Geun Shin ◽  
Jonghyun Eom
Keyword(s):  
Fluorescence Imaging ◽  
Multimodal Imaging ◽  
Imaging System ◽  
Imaging Technique ◽  
Photoacoustic Imaging ◽  
Imaging Systems ◽  
Complementary Information ◽  
Imaging Results ◽  
Fluorescence Imaging System ◽  
Fluorescence Images

A noncontact photoacoustic and fluorescence dual-modality imaging system is proposed, which integrates a fiber-based fluorescence imaging system with noncontact photoacoustic imaging using a specially fabricated double-cladding fiber (DCF) coupler and a DCF lens. The performance of the DCF coupler and lens was evaluated, and the feasibility of this new imaging system was demonstrated using simple tubing phantoms with black ink and fluorophore. Our imaging results demonstrated that the multimodal imaging technique can simultaneously acquire photoacoustic and fluorescence images without coming into contact with the sample. Consequently, the developed method is the first noncontact scheme among multimodal imaging systems that is integrated with a photoacoustic imaging system, which can provide varied and complementary information about the sample.

Contrast-enhanced ultrasound of the abdominal aorta – current status and future perspectives

VASA ◽  
2019 ◽  
Vol 48 (2) ◽  
pp. 115-125 ◽  
Author(s):  
Xin Li ◽  
Daniel Staub ◽  
Vasileios Rafailidis ◽  
Mohammed Al-Natour ◽  
Sanjeeva Kalva ◽  
...  
Keyword(s):  
Real Time ◽  
Vascular Diseases ◽  
Aneurysm Rupture ◽  
Vasa Vasorum ◽  
Current Status ◽  
Contrast Enhanced Ultrasound ◽  
Aortic Diseases ◽  
Cross Sectional ◽  
Vascular Abnormalities ◽  
Contrast Enhanced

Abstract. Ultrasound has been established as an important diagnostic tool in assessing vascular abnormalities. Standard B-mode and Doppler techniques have inherent limitations with regards to detection of slow flow and small vasculature. Contrast-enhanced ultrasound (CEUS) is a complementary tool and is useful in assessing both the macro- and microvascular anatomy of the aorta. CEUS can also provide valuable physiological information in real-time scanning sessions due to the physical and safety profiles of the administered microbubbles. From a macrovascular perspective, CEUS has been used to characterize aortic aneurysm rupture, dissection and endoleaks post-EVAR repair. With regard to microvasculature CEUS enables imaging of adventitial vasa vasorum thereby assessing aortic inflammation processes, such as monitoring treatment response in chronic periaortitis. CEUS may have additional clinical utility since adventitial vasa vasorum has important implications in the pathogenesis of aortic diseases. In recent years, there have been an increasing number of studies comparing CEUS to cross-sectional imaging for aortic applications. For endoleak surveillance CEUS has been shown to be equal or in certain cases superior in comparison to CT angiography. The recent advancement of CEUS software along with the ongoing development of drug-eluting contrast microbubbles has allowed improved targeted detection and real-time ultrasound guided therapy for aortic vasa vasorum inflammation and neovascularization in animal models. Therefore, CEUS is uniquely suited to comprehensively assess and potentially treat aortic vascular diseases in the future.

Recent Developments of Ambulatory Assessment Methods

2014 ◽  
Vol 25 (4) ◽  
pp. 279-287 ◽  
Author(s):  
Stefan Hey ◽  
Panagiota Anastasopoulou ◽  
André Bideaux ◽  
Wilhelm Stork
Keyword(s):  
Real Time ◽  
Information And Communication Technologies ◽  
New Technologies ◽  
Psychological Research ◽  
Ambulatory Assessment ◽  
Emotional States ◽  
Recent Developments ◽  
Potential Applications ◽  
Information And Communication ◽  
Physiological Sensors

Ambulatory assessment of emotional states as well as psychophysiological, cognitive and behavioral reactions constitutes an approach, which is increasingly being used in psychological research. Due to new developments in the field of information and communication technologies and an improved application of mobile physiological sensors, various new systems have been introduced. Methods of experience sampling allow to assess dynamic changes of subjective evaluations in real time and new sensor technologies permit a measurement of physiological responses. In addition, new technologies facilitate the interactive assessment of subjective, physiological, and behavioral data in real-time. Here, we describe these recent developments from the perspective of engineering science and discuss potential applications in the field of neuropsychology.

X-Ray Tomography for Electronic Packages

2000 ◽  
Author(s):  
Deepak Goyal
Keyword(s):  
3D Imaging ◽  
Development Time ◽  
Analytical Techniques ◽  
Electronic Packages ◽  
X Ray ◽  
Imaging Capability ◽  
Imaging Results ◽  
Key Drivers ◽  
Analytical Tools ◽  
Non Destructive

Abstract Next generation assembly/package development challenges are primarily increased interconnect complexity and density with ever shorter development time. The results of this trend present some distinct challenges for the analytical tools/techniques to support this technical roadmap. The key challenge in the analytical tools/techniques is the development of non-destructive imaging for improved time to information. This paper will present the key drivers for the non-destructive imaging, results of literature search and evaluation of key analytical techniques currently available. Based on these studies requirements of a 3D imaging capability will be discussed. Critical breakthroughs required for development of such a capability are also summarized.

Real-time control of nanoparticle-mediated thermal therapy using photoacoustic imaging

2020 ◽  
pp. 1-1
Author(s):  
Hisham Assi ◽  
Celina Yang ◽  
Elyas Shaswary ◽  
Mareck Tam ◽  
Jahan Tavakkoli ◽  
...  
Keyword(s):  
Real Time ◽  
Photoacoustic Imaging ◽  
Thermal Therapy ◽  
Real Time Control ◽  
Time Control

A new photoacoustic imaging platform for potential applications in prostate cancer

2020 ◽  
Author(s):  
Nidhi Singh ◽  
Emmanuel Cherin ◽  
Yohannes Soenjaya ◽  
Maninder Matharoo ◽  
Brandon Brisbane ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Photoacoustic Imaging ◽  
Potential Applications

IIOT and Real Time Data Analytics - Maximizing the Impact on Safety and Productivity

2021 ◽  
Author(s):  
Ryan Daher ◽  
Nesma Aldash
Keyword(s):  
Real Time ◽  
Case Studies ◽  
Data Analytics ◽  
Contact Tracing ◽  
Time Data ◽  
Seamless Integration ◽  
Location Services ◽  
Industrial Internet ◽  
Potential Applications ◽  
The Impact

Abstract With the global push towards Industry 4.0, a number of leading companies and organizations have invested heavily in Industrial Internet of Things (IIOT's) and acquired a massive amount of data. But data without proper analysis that converts it into actionable insights is just more information. With the advancement of Data analytics, machine learning, artificial intelligence, numerous methods can be used to better extract value out of the amassed data from various IIOTs and leverage the analysis to better make decisions impacting efficiency, productivity, optimization and safety. This paper focuses on two case studies- one from upstream and one from downstream using RTLS (Real Time Location Services). Two types of challenges were present: the first one being the identification of the location of all personnel on site in case of emergency and ensuring that all have mustered in a timely fashion hence reducing the time to muster and lessening the risks of Leaving someone behind. The second challenge being the identification of personnel and various contractors, the time they entered in productive or nonproductive areas and time it took to complete various tasks within their crafts while on the job hence accounting for efficiency, productivity and cost reduction. In both case studies, advanced analytics were used, and data collection issues were encountered highlighting the need for further and seamless integration between data, analytics and intelligence is needed. Achievements from both cases were visible increase in productivity and efficiency along with the heightened safety awareness hence lowering the overall risk and liability of the operation. Novel/Additive Information: The results presented from both studies have highlighted other potential applications of the IIOT and its related analytics. Pertinent to COVID-19, new application of such approach was tested in contact tracing identifying workers who could have tested positive and tracing back to personnel that have been in close proximity and contact therefore reducing the spread of COVID. Other application of the IIOT and its related analytics has also been tested in crane, forklift and heavy machinery proximity alert reducing the risk of accidents.

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