scholarly journals Action-outcome knowledge dissociates from behavior in obsessive-compulsive disorder following contingency degradation

2018 ◽  
Author(s):  
Matilde M. Vaghi ◽  
Rudolf N. Cardinal ◽  
Annemieke M. Apergis-Schoute ◽  
Naomi A. Fineberg ◽  
Akeem Sule ◽  
...  

ABSTRACTGoal-directed and habitual systems orchestrate action control. In disorders of compulsivity, their interplay seems disrupted and actions persist despite being inappropriate and without relationship to the overall goal. We manipulated action–outcome contingency to test whether actions are goal-directed or habitual in obsessive-compulsive disorder (OCD), the prototypical disorder of compulsivity, in which prominent theories have suggested that dysfunctional beliefs underlie the necessity for compulsive actions.OCD patients responded more than controls when an action was causally less related to obtaining an outcome, indicating excessive habitual responding. Patients showed intact explicit action–outcome knowledge but this was not translated normally into behavior; the relationship between causality judgment and responding was blunted. OCD patients’ actions were dissociated from explicit action-outcome knowledge, providing experimental support for the ego-dystonic nature of OCD and suggesting that habitual action is not sustained by dysfunctional belief.

2021 ◽  
Vol 18 (6) ◽  
pp. 545-552
Author(s):  
Seungho Kim ◽  
Sang Won Lee ◽  
Hyunsil Cha ◽  
Eunji Kim ◽  
Yongmin Chang ◽  
...  

Objective Although cognitive models of obsessive-compulsive disorder (OCD) fall into two categories: cognitive deficit models and dysfunctional belief models, these approaches have their own ways and have hardly been reconciled. Therefore, this study aimed to investigate the potential relationships between cognitive deficit (using the Wisconsin Card Sorting Task, WCST) and dysfunctional belief (measured by scales of dysfunctional beliefs) mediated by neural activity in OCD patients. Methods Thirty OCD patients and 30 healthy participants performed the WCST condition and a baseline MATCH condition during the 3T-functional magnetic resonance imaging (fMRI) acquisition. Results Engagement of additional frontoparietal networks with poorer performance of WCST was found during the fMRI scan in OCD patients. Selected regions of interest from activated regions have positive relationships with dysfunctional beliefs and with the unacceptable thoughts symptom dimension in the OCD group. Conclusion Findings suggest that alteration in frontoparietal networks related to cognitive deficits can be associated with dysfunctional beliefs while performing conventional neurocognitive tasks and this association with dysfunctional beliefs may be pronounced in the unacceptable thoughts domain-dominant OCD patients.


CNS Spectrums ◽  
2021 ◽  
pp. 1-33
Author(s):  
James McLauchlan ◽  
Emma M. Thompson ◽  
Ygor A. Ferrão ◽  
Euripedes C. Miguel ◽  
Lucy Albertella ◽  
...  

2021 ◽  
Vol 27 (1) ◽  
pp. 62-81
Author(s):  
Masoud Bagheri ◽  
◽  
Kazem Nematollah Zadeh Mahani ◽  
Maryam Pour Amrollahi ◽  
◽  
...  

Aims: Obsessive-Compulsive Disorder (OCD) is one of the severe psychological health problems imposing considerable social and economic costs on society. OCD debilitating symptoms can disrupt interpersonal relations, job performance, and life quality. The purpose of this study is to investigate the mediating role of alexithymia in the relationship between coping strategies and personality traits with OCD. Methods & Materials: This is a descriptive correlational study. The study population consists of all people with OCD referred to psychiatric clinics in Kerman City, Iran, during 2018-2019. Of this population, 200 patients were selected using a convenience sampling method. Research instruments included the ways of coping questionnaire, NEO five-factor personality inventory, Toronto alexithymia scale, and Maudsley obsessive-compulsive test. The obtained data were analyzed using the Pearson correlation test and simultaneous and hierarchical regression in SPSS v. 23. Findings: Personality traits had a negative significant correlation with alexithymia (r=0.523, P<0.000) and OCD (r=0.253, P<0.000). Alexithymia had a significant positive correlation with OCD (r=0.272, P<0.000). There was no correlation between problem-focused coping and alexithymia (r=-0.045, P<0.531). There was a positive correlation between emotion-focused coping and OCD (r=0.198, P<0.000). The fit indices indicated a good fit of the proposed model (P<0.005). Conclusion: Alexithymia, as a mediator of the relationship between coping styles and personality traits with OCD, plays an essential role in improving the psychological health of people with OCD.


2021 ◽  
Author(s):  
Yanrong Wang ◽  
Shaohua Chang ◽  
Xiaomin Ma ◽  
Jiying Li ◽  
Ruixia Zhang ◽  
...  

Abstract We examined the relationship between facial morphological features and clinical characteristics of adolescents with obsessive-compulsive disorder (OCD). The enrolled study sample comprised 40 adolescents diagnosed with OCD using the Obsessive Compulsive Inventory Child Version (OCI-CV) and 38 healthy controls (HCs). Facial photos, 21 facial diameters, and nine facial angles were collected using image software. In males, lower lip red height was significantly lower in OCD patients than in HCs (P < 0.05); no significant differences were observed in other facial indicators (all P > 0.05). In females, the nasolabial angle was smaller in OCD patients than in HCs (P < 0.05); no significant differences were observed in other facial indicators (all P > 0.05). The difference in lower lip red height between the OCD group and HC group was positively correlated with mental neutralization symptoms (r = 0.401, P < 0.05). Our findings highlight the relationship between facial and clinical characteristics in OCD patients.


2008 ◽  
Vol 39 (9) ◽  
pp. 1491-1501 ◽  
Author(s):  
G. Nestadt ◽  
C. Z. Di ◽  
M. A. Riddle ◽  
M. A. Grados ◽  
B. D. Greenberg ◽  
...  

BackgroundObsessive–compulsive disorder (OCD) is probably an etiologically heterogeneous condition. Many patients manifest other psychiatric syndromes. This study investigated the relationship between OCD and co-morbid conditions to identify subtypes.MethodSeven hundred and six individuals with OCD were assessed in the OCD Collaborative Genetics Study (OCGS). Multi-level latent class analysis was conducted based on the presence of eight co-morbid psychiatric conditions [generalized anxiety disorder (GAD), major depression, panic disorder (PD), separation anxiety disorder (SAD), tics, mania, somatization disorders (Som) and grooming disorders (GrD)]. The relationship of the derived classes to specific clinical characteristics was investigated.ResultsTwo and three classes of OCD syndromes emerge from the analyses. The two-class solution describes lesser and greater co-morbidity classes and the more descriptive three-class solution is characterized by: (1) an OCD simplex class, in which major depressive disorder (MDD) is the most frequent additional disorder; (2) an OCD co-morbid tic-related class, in which tics are prominent and affective syndromes are considerably rarer; and (3) an OCD co-morbid affective-related class in which PD and affective syndromes are highly represented. The OCD co-morbid tic-related class is predominantly male and characterized by high conscientiousness. The OCD co-morbid affective-related class is predominantly female, has a young age at onset, obsessive–compulsive personality disorder (OCPD) features, high scores on the ‘taboo’ factor of OCD symptoms, and low conscientiousness.ConclusionsOCD can be classified into three classes based on co-morbidity. Membership within a class is differentially associated with other clinical characteristics. These classes, if replicated, should have important implications for research and clinical endeavors.


Author(s):  
Rebecca J. Hamblin ◽  
Jennifer Moonjung Park ◽  
Monica S. Wu ◽  
Eric A. Storch

Individuals with obsessive-compulsive disorder (OCD) often have good insight into the irrational nature of their obsessions and the excessive character of their compulsions, but insight exists along a continuum and is markedly poor in some patients. This chapter reviews the assessment and phenomenological correlates of variable insight in OCD in both pediatric and adult populations. It reviews the definition of insight and its relationship to the evolution of diagnostic criteria for obsessive-compulsive disorder, as well as the major assessment tools used to measure and quantify insight for clinical and research purposes. The relationships between insight and clinical characteristics of OCD, including symptom severity, comorbidity, and treatment response are reviewed, followed by a review of neurobiological correlates of insight and the relationship between poor insight and schizophrenia spectrum disorders.


Author(s):  
Barbara Cludius ◽  
Anna K. Mannsfeld ◽  
Alexander F. Schmidt ◽  
Lena Jelinek

Abstract According to psychodynamic and cognitive models of obsessive–compulsive disorder (OCD), anger and aggression play an important role in the development and maintenance of the disorder. (Sub-) clinical samples with OCD have reported higher anger and anger suppression. Patients with checking-related symptoms of OCD showed a less aggressive self-concept as assessed by an Implicit Association Test (IAT). This study assessed anger and aggressiveness self-concepts in OCD as well as possible mediators of the link between OCD and aggressiveness. A total of 48 patients with OCD and 45 healthy controls were included. Measures included the State-Trait Anger Expression Inventory-II and an aggressiveness self-concept IAT (Agg-IAT). An inflated sense of responsibility, non-acceptance of emotions, and social desirability were tested as mediators. As expected, patients with OCD reported higher trait anger and anger suppression compared to healthy controls. Contrary to hypotheses, the aggressiveness self-concept (Agg-IAT) did not differ between groups. The inflated sense of responsibility mediated the relationship between group and anger suppression. Non-acceptance of negative emotions mediated the relationship between group and trait anger, as well as anger suppression. However, comorbidities and medication may account for some effect in anger suppression. Elevated trait anger and anger suppression in OCD patients could be explained by dysfunctional beliefs or maladaptive emotion regulation strategies. Emotion regulation therapy might help to enhance awareness and acceptance of emotions and possibly improve treatment outcomes.


2020 ◽  
pp. 008124632096153
Author(s):  
Sadi Cordelia Bambo ◽  
Solomon Mashegoane

The study investigated the mediator role of death obsession in the relationship between pregnancy-related anxiety and prenatal obsessive-compulsive disorder among pregnant women in the Capricorn district, South Africa. Two hundred and six conveniently selected respondents completed questionnaires individually. Statistically significant associations were found between pregnancy-related anxiety and death obsession, death obsession and prenatal obsessive-compulsive disorder, and pregnancy-related anxiety and prenatal obsessive-compulsive disorder ( ps ⩽ .05). Analysis further showed that death obsession mediates the relationship between pregnancy-related anxiety and both composite scores of a prenatal obsessive-compulsive disorder measure (Obsessive-Compulsive Inventory–Revised) and most of its components. The findings suggest that death obsession is a likely mediator that has to be studied further.


2019 ◽  
Vol 94 ◽  
pp. 152116 ◽  
Author(s):  
Paula Vigne ◽  
Bruno F.T. Simões ◽  
Gabriela B. de Menezes ◽  
Pedro P. Fortes ◽  
Rafaela V. Dias ◽  
...  

1992 ◽  
Vol 7 (2) ◽  
pp. 53-59 ◽  
Author(s):  
P Ronchi ◽  
M Abbruzzese ◽  
S Erzegovesi ◽  
G Diaferia ◽  
G Sciuto ◽  
...  

SummaryThis study presents the clinical and demographic characteristics of a sample of 131 patients, who met DSM III-R criteria for obsessive-compulsive disorder (OCD). Our aim was to compare our epidemiological data with non-European research, and to investigate the relationship between OCD symptoms and other clinical features, ie other Axis I concomitant disturbances, personality disorders (Axis II) and family history. Furthermore, we evaluated the age at onset distribution according to sex, family history and presence/absence of a comorbid diagnosis of mood disorder, by means of survival analysis.


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