Phase-contrast X-ray CT image of breast tumor

1998 ◽  
Vol 5 (3) ◽  
pp. 1133-1135 ◽  
Author(s):  
Tohoru Takeda ◽  
Atsushi Momose ◽  
Ei Ueno ◽  
Yuji Itai
Keyword(s):  
Breast Tumor ◽  
Phase Contrast ◽  
Soft Tissues ◽  
Ct Images ◽  
Human Breast ◽  
Human Breast Tumor ◽  
Synchrotron Source ◽  
X Ray ◽  
Optical Images ◽  
Internal Structures

Phase-contrast X-ray CT images generated by differences in refractive indices can be used to visualize the internal structures of soft tissues without contrast enhancement. In this study, imaging of human breast tumor was performed on formalin-fixed samples. Experiments were carried out at the synchrotron source of the Photon Factory, Tsukuba, Japan. The X-ray energy was adjusted to 17.7 keV. Phase-contrast X-ray CT images revealed various structures of human breast tumor as clearly as optical images.

scholarly journals Principles of Different X-ray Phase-Contrast Imaging: A Review

2021 ◽  
Vol 11 (7) ◽  
pp. 2971
Author(s):  
Siwei Tao ◽  
Congxiao He ◽  
Xiang Hao ◽  
Cuifang Kuang ◽  
Xu Liu
Keyword(s):  
Biological Samples ◽  
Phase Contrast ◽  
Recent Progress ◽  
Phase Contrast Imaging ◽  
Contrast Imaging ◽  
X Ray ◽  
X Ray Imaging ◽  
Internal Structures ◽  
X Ray Absorption ◽  
Made In

Numerous advances have been made in X-ray technology in recent years. X-ray imaging plays an important role in the nondestructive exploration of the internal structures of objects. However, the contrast of X-ray absorption images remains low, especially for materials with low atomic numbers, such as biological samples. X-ray phase-contrast images have an intrinsically higher contrast than absorption images. In this review, the principles, milestones, and recent progress of X-ray phase-contrast imaging methods are demonstrated. In addition, prospective applications are presented.

scholarly journals A Method to Monitor mRNA Levels in Human Breast Tumor Cells Obtained by Fine-needle Aspiration

1997 ◽  
Vol 6 (6) ◽  
pp. 353-360 ◽  
Author(s):  
Majella S. de Lange ◽  
Bert Top ◽  
Caro Lambrechts ◽  
Riks A. Maas ◽  
Hans L. Peterse ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Fine Needle Aspiration ◽  
Breast Tumor ◽  
Needle Aspiration ◽  
Mrna Levels ◽  
Human Breast ◽  
Human Breast Tumor ◽  
Breast Tumor Cells ◽  
Fine Needle

Induction of Apoptosis by Hybrid Liposomes without Antitumor Drugs toward Human Breast Tumor Cells

2003 ◽  
Vol 36 (9) ◽  
pp. 1127-1129 ◽  
Author(s):  
Hideaki Nagami ◽  
Keiichi Yamamoto ◽  
Hideaki Ichihara ◽  
Yoko Matsumoto ◽  
Ryuichi Ueoka
Keyword(s):  
Tumor Cells ◽  
Breast Tumor ◽  
Antitumor Drugs ◽  
Human Breast ◽  
Human Breast Tumor ◽  
Breast Tumor Cells ◽  
Induction Of Apoptosis

Accumulation of99mTc-HMPAO and99mTc-ECD in rodent and human breast tumor cell linesin vitro

1997 ◽  
Vol 11 (2) ◽  
pp. 95-99 ◽  
Author(s):  
James R. Ballinger ◽  
Jill Duncan ◽  
H. Annie Hua ◽  
Masanori Ichise
Keyword(s):  
Tumor Cell ◽  
Breast Tumor ◽  
Human Breast ◽  
Breast Tumor Cell ◽  
Human Breast Tumor ◽  
Human Breast Tumor Cell

Visualization of microvasculature and thrombi by X-ray phase-contrast computed tomography in hepatocellular carcinoma

2016 ◽  
Vol 23 (2) ◽  
pp. 600-605 ◽  
Author(s):  
Jianbo Jian ◽  
Hao Yang ◽  
Xinyan Zhao ◽  
Ruijiao Xuan ◽  
Yujie Zhang ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Hepatocellular Carcinoma ◽  
Phase Contrast ◽  
Soft Tissues ◽  
Three Dimensional ◽  
X Ray ◽  
Density Distributions ◽  
Fine Structures ◽  
Tumor Growth And Metastasis ◽  
Micrometer Scale

Visualization of the microvascular network and thrombi in the microvasculature is a key step to evaluating the development of tumor growth and metastasis, and influences treatment selection. X-ray phase-contrast computed tomography (PCCT) is a new imaging technique that can detect minute changes of density and reveal soft tissues discrimination at micrometer-scale resolution. In this study, six human resected hepatocellular carcinoma (HCC) tissues were investigated with PCCT. A histological stain was added to estimate the accuracy of PCCT. The results showed that the fine structures of the microvasculature (measuring 30–100 µm) and thrombi in tiny blood vessels were displayed clearly on imaging the HCC tissues by PCCT. Moreover, density distributions of the thrombi were obtained, which could be reliably used to distinguish malignant from benign thrombi in HCC. In conclusion, PCCT can clearly show the three-dimensional subtle structures of HCC that cannot be detected by conventional absorption-based computed tomography and provides a new method for the imageology of HCC.

Total Synthesis of a Human Breast Tumor Associated Antigen

1995 ◽  
Vol 117 (29) ◽  
pp. 7840-7841 ◽  
Author(s):  
Mark T. Bilodeau ◽  
Tae Kyo Park ◽  
Shuanghua Hu ◽  
John T. Randolph ◽  
Samuel J. Danishefsky ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Breast Tumor ◽  
Human Breast ◽  
Human Breast Tumor ◽  
Tumor Associated Antigen

scholarly journals Polypyridyl Ruthenium Complexes: Novel DNA-Intercalating Agents against Human Breast Tumor

2017 ◽  
Author(s):  
João Barolli ◽  
Rodrigo Corrêa ◽  
Fabio Miranda ◽  
Juliana Ribeiro ◽  
Carlos Bloch Jr. ◽  
...  
Keyword(s):  
Breast Tumor ◽  
Ruthenium Complexes ◽  
Human Breast ◽  
Human Breast Tumor ◽  
Intercalating Agents

Subtle changes in network composition impact the biodistribution and tumor accumulation of nanogels

2018 ◽  
Vol 54 (83) ◽  
pp. 11777-11780 ◽  
Author(s):  
Ilona Zilkowski ◽  
Ioanna Theodorou ◽  
Krystyna Albrecht ◽  
Frederic Ducongé ◽  
Jürgen Groll
Keyword(s):  
Breast Tumor ◽  
Tumor Targeting ◽  
Near Infrared ◽  
Side Chain ◽  
Human Breast ◽  
Human Breast Tumor ◽  
Tumor Xenografts ◽  
Network Composition ◽  
Tumor Accumulation

We studied the effect of subtle changes in side-chain chemistry and labelling with near infrared fluorophores of nanogels (NGs) prepared from thiolated poly(glycidol) on in vivo biodistribution in mice bearing human breast tumor xenografts. Side chain chemistry as well as labelling clearly influenced tumor targeting and overall biodistribution.

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