AAA screening in adults with ASD: a retrospective cohort study

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Marios Adamou ◽  
Sarah Louise Jones ◽  
Stephanie Wetherhill

Purpose The Adult Asperger Assessment (AAA), comprising the Autism Questionnaire, the Empathy Quiotient and the Relatives Questionnaire is a commonly used screening tool designed to identify adults who may benefit from a further clinical assessment for autism spectrum disorder. The purpose of this paper is to investigate the usefulness of this screening measure in a clinical setting. Design/methodology/approach This retrospective cohort study comprised of 192 service users referred for diagnostic assessment of Autism by a specialist service of the National Health Service. The authors evaluated the diagnostic accuracy of the AAA by investigating if the Autism Questionnaire, the Empathy Quiotient and the Relatives Questionnaire were able to predict the diagnostic outcome of Autism in a clinical setting. Findings Scores from the Relatives Questionnaire can accurately predict diagnostic outcome. No evidence of accuracy for the Autism Questionnaire or the Empathy Quotient was apparent. Based on the findings, the authors recommend clinicians are cautious when interpreting results of the AAA. Research limitations/implications It should be acknowledged that the results may not be generalisable to whole populations. Also, the authors used the full item versions of the scales; therefore, the findings are most applicable to studies which did similar. Originality/value This study highlights the need for investigation into the lack of validation of commonly used screening measures in autistic populations.

2012 ◽  
Vol 56 (11) ◽  
pp. 6041-6043 ◽  
Author(s):  
Tark Kim ◽  
Heungsup Sung ◽  
Yu-Mi Lee ◽  
Hyo-Lim Hong ◽  
Sung-Han Kim ◽  
...  

ABSTRACTThere are no data on the efficacy of secondary prophylaxis againstPneumocystispneumonia after solid organ transplantation. Therefore, we investigated the rate of recurrence ofPneumocystispneumonia after solid organ transplantation in a retrospective cohort study. Between 2005 and 2011, a total of 41 recipients recovered fromPneumocystispneumonia. Of these, 22 (53.7%) received secondary prophylaxis. None of the 41 recipients experienced recurrence ofPneumocystispneumonia during the follow-up, regardless of secondary prophylaxis.


2020 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Claire Johnson ◽  
Iva Bien-Aimé ◽  
Lise Dubois

Purpose Very little is known about how weight gain during incarceration influences the health of people living in Canadian federal penitentiaries. To fill this knowledge gap, this study aims to determine how the observed weight gain influenced the development of obesity-related chronic diseases during incarceration. Design/methodology/approach This retrospective cohort study examined the association between weight gain and obesity-related chronic diseases for 1,420 participants incarcerated in federal penitentiaries in Ontario, New Brunswick and Nova Scotia. To participate, individuals had to be incarcerated for at least six months at the time of the study (2016–2017). Current anthropometric data were measured or taken from medical records, then compared to anthropometric data at the beginning of incarceration (mean follow-up of 5.0 years) to determine weight change (kg) and body mass index change (kg/m2) during incarceration. Then, information about obesity-related chronic diseases was drawn from the participants’ medical records. Findings Chi-square and nonparametric median comparison tests were performed to detect statistically significant changes in anthropometric data, to determine if a relationship was present. This study observed a significant association between weight gain and disease development for many types of obesity-related chronic diseases (e.g. cancer, type 2 diabetes, hypertension, dyslipidemia and sleep apnea). This confirmed an association between weight gain and chronic disease development in the prison population. Originality/value Participants who gained a significant amount of weight, during incarceration, were also more frequently diagnosed with obesity-related chronic diseases. These findings suggest that weight gain may contribute to the deterioration of peoples’ health during incarceration.


2020 ◽  
Vol 158 (6) ◽  
pp. S-1161
Author(s):  
Amrit K. Kamboj ◽  
Amandeep Gujral ◽  
Elida Voth ◽  
Daniel Penrice ◽  
Jessica McGoldrick ◽  
...  

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