Age at death and comorbidity of dementia-related disorders among individuals with autism spectrum disorder

2019 ◽  
Vol 5 (4) ◽  
pp. 293-302 ◽  
Author(s):  
Lucy Barnard-Brak ◽  
David Richman ◽  
Zhanxia Yang

Purpose Autism spectrum disorder (ASD) is a lifelong disorder that requires intervention and support services for a growing geriatric population. The purpose of this paper is to examine the mean age at death of individuals with ASD and subsequent comorbidity with Alzheimer’s disease, and any form of dementia, as a whole and according to sex. Design/methodology/approach Data consisted of 1,754 individuals who had an ASD listed as one of the causes of deaths from the National Vital Statistics System with data from 1999 to 2015. In the current study, the authors present contradictory results with a mean age at death for individuals with ASD was 68 years by adjusting for changing prevalence rates. Findings Females with ASD had a higher mean age at death than males with ASD; consistent with the trend in the sex differences in the general population. The results of the current study also indicate that individuals with ASD were, in fact, less likely than the general population to have Alzheimer’s disease or a form of dementia. However, males with ASD were significantly more likely to have acquired Alzheimer’s disease or a form of dementia as compared to females with ASD. Originality/value Guan and Li (2017) reported a mean age at death of 36 years old for individuals with ASD, which was subsequently reported in the mass media, most notably CNN. The authors contend that this study provides a more accurate estimate mean age at death.

2018 ◽  
Vol 48 ◽  
pp. 117-130 ◽  
Author(s):  
Sarah Parisot ◽  
Sofia Ira Ktena ◽  
Enzo Ferrante ◽  
Matthew Lee ◽  
Ricardo Guerrero ◽  
...  

2018 ◽  
Vol 19 (9) ◽  
pp. 876-880 ◽  
Author(s):  
Athanasios Alexiou ◽  
Georgia Soursou ◽  
Nagendra Sastry Yarla ◽  
Ghulam Md Ashraf

2021 ◽  
Vol 292 ◽  
pp. 03062
Author(s):  
Siyang Wei ◽  
Zilan Xin ◽  
Yuankai Zhang

With the natural and social environment changing, people’s mental health is facing severe challenges. Many people are suffering from mental disorders in the present day. A large part of mental disorders can be linked with the nerve system. And nerve system disorders tend to be associated with the development of nerve systems. The gene and the environment can play an important role in the development of the body, and abnormal genes and detrimental environmental factors can contribute a lot to nerve system disorders. Previous research has studied the occurrence and gene-and-environmental impact of many nerve system disorders. Among them, this essay chooses three kinds of disorders: Alzheimer’s disease (AD), Phobia, and Autism Spectrum Disorder, which can cause a lot of trouble in people’s daily life. In this essay, we are to study the occurrence of some nerve systems’ disorders and hope to study the genetic and environmental contribution of these disorders. These three disorders gain a lot of attention as they are very common, and they can partly reflect the contribution of genes and the environment.


2019 ◽  
Vol 50 (1) ◽  
pp. 180-188 ◽  
Author(s):  
K. Jussila ◽  
M. Junttila ◽  
M. Kielinen ◽  
H. Ebeling ◽  
L. Joskitt ◽  
...  

Abstract Sensory abnormalities (SAs) are recognized features in Autism Spectrum Disorder (ASD), and a relationship between SAs and ASD traits is also suggested in general population. Our aims were to estimate the prevalence of SAs in three different settings, and to study the association between SAs and quantitative autism traits (QAT) using the Autism Spectrum Screening Questionnaire (ASSQ) and a parental questionnaire. In an epidemiological population of 8-year-old children (n = 4397), the prevalence of SAs was 8.3%, in an ASD sample (n = 28), 53.6%, and in a non-ASD sample (n = 4369), 8.0%, respectively. Tactile and auditory hypersensitivity predicted an ASD diagnosis. The ASSQ was able to differentiate children with and without SA. In conclusion, QAT level and SAs were associated in all study samples.


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