Peri-intraventricular hemorrhage and arterial blood pressure fluctuation in the critically ill preterm infant

Author(s):  
V.F. Puccio ◽  
M. Soliani ◽  
G. Carrera ◽  
M.L. Massone ◽  
A. Macerata ◽  
...  
2007 ◽  
Vol 104 (4) ◽  
pp. 853-856 ◽  
Author(s):  
Yoshihiro Fujiwara ◽  
Hiroshi Ito ◽  
Yusuke Asakura ◽  
Yuko Sato ◽  
Kimitoshi Nishiwaki ◽  
...  

PEDIATRICS ◽  
1992 ◽  
Vol 89 (4) ◽  
pp. 643-647 ◽  
Author(s):  
Lena Hellström-Westas ◽  
Nils W. Svenningsen ◽  
Angela H. Bell ◽  
Liselotte Skov ◽  
Gorm Greisen

During surfactant treatment of respiratory distress syndrome, 23 premature newborns were investigated with continuous amplitude-integrated electroencephalography (cerebral function monitors). Simultaneously, arterial blood pressure and transcutaneous blood gas values were recorded. A short(<10 minutes) but significant decrease in cerebral activity was seen in almost all neonates immediately after the surfactant instillation, in spite of an improved pulmonary function. In 21 of 23 neonates, a transient fall in mean arterial blood pressure of 9.3 mm Hg (mean) occurred coincidently with the cerebral reaction. Neonates in whom intraventricular hemorrhage developed tended to have lower presurfactant mean arterial blood pressure (P> .05), but they had a significantly lower mean arterial blood pressure after surfactant instillation (P < .05). No other differences were found between neonates in whom intraventricular hemorrhage developed and those without intraventricular hemorrhage. The present findings demonstrate that an acute cerebral dysfunction may occur after surfactant instillation. In some vulnerable neonates with arterial hypotension and severe pulmonary immaturity,the fall in mean arterial blood pressure may increase the risk of cerebral complications and could be related to an unchanged rate of intraventricular hemorrhage after surfactant treatment.


2010 ◽  
Vol 11 (1) ◽  
pp. 75-81 ◽  
Author(s):  
Philippe Chessex ◽  
Minesh Khashu ◽  
Adele Harrison ◽  
Martin Hosking ◽  
Michael Sargent ◽  
...  

PEDIATRICS ◽  
1990 ◽  
Vol 85 (1) ◽  
pp. 138-138
Author(s):  
JEFFREY PERLMAN

In Reply.— The purpose of the study cited by Dr Argent et al was to elucidate potential mechanisms for the fluctuations in arterial blood pressure observed previously. We agree with the authors that the cough-like Valsalva maneuvers contribute significantly to the circulatory variablility. The data also indicate the close temporal relationship between apneic pauses and stable blood pressure. We support the statement of the authors that ventilator support should be optimized before paralysis. Moreover, other "less noxious" interventions, such as sedation, might have similar beneficial effects regarding stabilization of blood pressure.


PEDIATRICS ◽  
1984 ◽  
Vol 74 (3) ◽  
pp. 350-353
Author(s):  
Daniel G. Batton ◽  
Jonathan Hellmann ◽  
Elizabeth E. Nardis

Pneumothorax has been associated with intraventricular hemorrhage in premature infants, although the mechanism for this relationship is not clear. Because alterations in cerebral blood flow are believed to be important in the pathogenesis of intraventricular hemorrhage, the effect of induced pneumothorax and subsequent evacuation on the cerebral circulation in 16 newborn dogs was evaluated. Continuous Doppler ultrasound was used to monitor changes in cerebral blood velocity. Pneumothorax was induced by slow infusion (5 cc/kg/min) or rapid infusion (5 to 10 seconds) of air to reduce mean arterial blood pressure to half of base-line levels. Both methods of pneumothorax induction resulted in significant elevations of central venous pressure and intrapleural pressure, whereas mean arterial blood pressure and cerebral blood velocity decreased significantly. In each group, the pneumothorax was evacuated either by slow withdrawal of air (10 cc/kg/min) or as rapidly as possible. Rapid evacuation of air resulted in an immediate increase in mean arterial blood pressure and cerebral blood velocity to supranormal levels. Slow evacuation led to a more gradual normalization of mean arterial blood pressure and cerebral blood velocity. It is suggested that the precipitous increases in mean arterial blood pressure and cerebral blood velocity following rapid evacuation of a tension pneumothorax may account for the observed association between pneumothorax and intraventricular hemorrhage in premature infants.


2021 ◽  
Vol 39 (3) ◽  
pp. 188-191
Author(s):  
Jiyong Shin ◽  
Jihee Ko ◽  
Minju Kim ◽  
Chul-Hoo Kang ◽  
Jay Chol Choi ◽  
...  

Cerebral intraventricular hemorrhage (IVH) is an extremely rare complication of carotid artery stenting (CAS). Fully dilated terminal arteries of a chronic, severely stenosed proximal artery could be ruptured by impaired autoregulation of cerebral blood flow. Hyperperfusion syndrome can occur even if there is no blood pressure fluctuation during the CAS. We report a case of an isolated IVH that occurred hours after CAS.


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