A Framework for Physiological Response Prediction with Joint Activity State optimization

2018 ◽  
Author(s):  
Laura Gonzalez ◽  
Boxuan Zhong ◽  
Edgar Lobaton
Keyword(s):  
Physiological Response ◽  
Response Prediction ◽  
Joint Activity ◽  
Activity State

scholarly journals Activity-Aware Physiological Response Prediction Using Wearable Sensors

Inventions ◽  
2017 ◽  
Vol 2 (4) ◽  
pp. 32 ◽  
Author(s):  
Namita Lokare ◽  
Boxuan Zhong ◽  
Edgar Lobaton
Keyword(s):  
Physiological Response ◽  
Wearable Sensors ◽  
Response Prediction

Preliminary Report of a Comparative Study of Seminiferous Tubular Epithelium from Rats Flown on Cosmos 1887 and SL3

1988 ◽  
Vol 46 ◽  
pp. 276-277
Author(s):  
Walter J. Sapp ◽  
D.E. Philpott ◽  
C.S. Williams ◽  
K. Kato ◽  
J. Stevenson ◽  
...  
Keyword(s):  
Space Flight ◽  
Physiological Response ◽  
Preliminary Report ◽  
Complete Recovery ◽  
Environmental Constraints ◽  
Tubular Epithelium ◽  
Testicular Weight ◽  
Testicular Morphology ◽  
Normal Offspring ◽  
Rats And Mice

Space flight, with its unique environmental constraints such as immobilization, decreased and increased pressures, and radiation, is known to affect testicular morphology and spermatogenesis. Selye, summarized the manifestations of physiological response to nonspecific stress and he pointed out that atrophy of the gonads always occurred. Reports of data collected from two dogs flown in space for 22 days (Cosmos 110) indicate that there was an increase of 30 to 70% atypical spermatozoa when compared to ground based controls. Seventy-five days after the flight the abnormalities had decreased to the high normal value of 30% and mating of these dogs after this period produced normal offspring, suggesting complete recovery. Effects of immobilization and increased gravity were investigated by spinning rats and mice at 2x g for 8-9 weeks. A decrease in testicular weight was noted in spun animals when compared to controls. Immobilization has been show to cause arrest of spermatogenesis in Macaca meminstrins.

Reduction of spermatogonia and testosterone in rat testes flown on space lab-3

1986 ◽  
Vol 44 ◽  
pp. 248-249
Author(s):  
Delbert E. Philpott ◽  
W. Sapp ◽  
C. Williams ◽  
T. Fast ◽  
J. Stevenson ◽  
...  
Keyword(s):  
Social Interaction ◽  
Social Status ◽  
Population Size ◽  
Physiological Response ◽  
Social Rank ◽  
Reproductive Function ◽  
Testicular Development ◽  
Organ Weights ◽  
Reproductive Maturation ◽  
Metabolic Activities

Space Lab 3 (SL-3) was flown on Shuttle Challenger providing an opportunity to measure the effect of spaceflight on rat testes. Cannon developed the idea that organisms react to unfavorable conditions with highly integrated metabolic activities. Selye summarized the manifestations of physiological response to nonspecific stress and he pointed out that atrophy of the gonads always occurred. Many papers have been published showing the effects of social interaction, crowding, peck order and confinement. Flickinger showed delayed testicular development in subordinate roosters influenced by group numbers, social rank and social status. Christian reported increasing population size in mice resulted in adrenal hypertrophy, inhibition of reproductive maturation and loss of reproductive function in adults. Sex organ weights also declined. Two male dogs were flown on Cosmos 110 for 22 days. Fedorova reported an increase of 30 to 70% atypical spermatozoa consisting of tail curling and/or the absence of a tail.

Physiological response of normal adult horses to a low-residue liquid diet

2003 ◽  
Vol 23 (7) ◽  
pp. 310-317
Author(s):  
Virginia A. Buechner-Maxwell ◽  
Francois Elvinger ◽  
Craig D. Thatcher ◽  
Micheal J. Murray ◽  
Nathanial A. White ◽  
...  
Keyword(s):  
Physiological Response ◽  
Liquid Diet ◽  
Normal Adult

A Comparison of Methods for the Measurement of Activated Factor VII

1992 ◽  
Vol 68 (03) ◽  
pp. 301-305 ◽  
Author(s):  
S Kitchen ◽  
R G Malia ◽  
F E Preston
Keyword(s):  
Factor Viia ◽  
Epidemiological Studies ◽  
Factor Vii ◽  
Haemophilia A ◽  
Reference Ranges ◽  
Activated Factor Vii ◽  
Normal Individuals ◽  
Antigen Assay ◽  
Activity State ◽  
Almost All

SummaryA number of different methods are available for the measurement of factor VIIa. Almost all of these employ ratios of two different measurements of factor VII. In order to determine which is the most sensitive to activated factor VII we have compared currently available methods in the following groups: two patients with haemophilia A following treatment with activated recombinant factor VII (rVII a); 6 normal plasmas during cold promoted activation of factor VII; normal individuals (n = 23); and patients with unequivocal disseminated intravascular coagulation (DIC, n = 19). Factor VII was measured in an amidolytic assay (VII: Amid) and an antigen assay (VII:Ag). Clotting activity was measured using rabbit (VII:C Rab), human (VII:C Hum) and bovine (VII:C Bov) thromboplastin.Of the clotting assays the most sensitive to the presence of factor VIIa was that which utilised bovine thromboplastin. Amidolytic and immunological measurements were unaffected by the activity state of factor VII. The ratios VII:C Rab/VII: Ag and VII:C Rab/VII:Amid were insensitive to activated factor VII. The ratios most sensitive to the presence of factor VII a were VII:C Bov/VII: Amid and VII: C Bov/VII:Ag. The ratios VII:C Bov/VII:C Rab and VII:C Bov/VII:C Hum are less sensitive but have the advantage for epidemiological studies of narrower reference ranges.

Liquid Biopsies in the Management of Bladder Cancer: Next-Generation Biomarkers for Diagnosis, Surveillance, and Treatment-Response Prediction

2017 ◽  
Vol 22 (5-6) ◽  
pp. 389-401 ◽  
Author(s):  
Yu Yang ◽  
Catherine R. Miller ◽  
Antonio Lopez-Beltran ◽  
Rodolfo Montironi ◽  
Monica Cheng ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Treatment Response ◽  
Response Prediction ◽  
Next Generation ◽  
Liquid Biopsies ◽  
Treatment Response Prediction

Tumor Necrosis Factor Alpha Converting Enzyme (TACE) as Possible Therapeutic Target in SARS-CoV-2 Induced Acute Respiratory Distress Syndrome (ARDS)

2020 ◽  
Author(s):  
Joao Batista Junior
Keyword(s):  
Tumor Necrosis Factor ◽  
Tumor Necrosis Factor Alpha ◽  
Tumor Necrosis ◽  
Inflammatory Responses ◽  
Converting Enzyme ◽  
Necrosis Factor Alpha ◽  
Tace Inhibitors ◽  
Factor Alpha ◽  
Activity State ◽  
Necrosis Factor

<div>This study reveals, for the first time, that rosiglitazone and pioglitazone, two thiazolidinedione drugs already approved as therapeutic agents to treat type II diabetes, were found to bind favorably to tumor necrosis factor alpha converting enzyme catalytic site with highlighted binding features.</div><div><br></div>This study suggests that rosiglitazone and pioglitazone, acting as TACE inhibitors agents might avoid or attenuate the hyperexcitability proteolytic activity state of TACE, represent a new potential therapeutic approach to treat SARS-CoV-2 infection-associated severe systemic inflammatory responses observed among severely or critically ill SARS-CoV-2 patients and, consequently, to diminish severe inflammatory‐induced lung injury, ARDS development and death rates.<br><br>

Sign in / Sign up

Export Citation Format

Share Document