Instrumentation and experiment design for in-vitro interface temperature measurement during the insertion of an orthopaedic implant

2008 ◽  
Author(s):  
W. Xu
Keyword(s):  
Temperature Measurement ◽  
Experiment Design ◽  
Interface Temperature ◽  
Orthopaedic Implant

Interface Temperature Measurement and Experimental Studies of Super-High Speed Polishing of CVD Diamond Films

2010 ◽  
Vol 135 ◽  
pp. 271-276
Author(s):  
Shu Tao Huang ◽  
Li Zhou ◽  
Li Fu Xu
Keyword(s):  
Stainless Steel ◽  
Temperature Measurement ◽  
Temperature Rise ◽  
Diamond Film ◽  
High Speed ◽  
Experimental Studies ◽  
Pure Titanium ◽  
Cvd Diamond ◽  
Interface Temperature ◽  
Cvd Diamond Film

Super-high speed polishing of diamond film is a newly proposed method due to its outstanding features such as low cost and simple apparatus. The interface temperature rise is due to the friction force and the relative sliding velocity between the CVD diamond film and the polishing metal plate surface. In this paper, the interface temperature rise in super-high speed polishing of CVD diamond film was investigated by using the single-point temperature measurement method. Additionally, the influence of polishing plate material on the characteristics of super-high speed polishing has been studied. The results showed that cast iron is not suitable for super-high polishing, while both 0Cr18Ni9 stainless steel and pure titanium can be used for the super-high polishing of CVD diamond film. The quality and efficiency of polishing with 0Cr18Ni9 stainless steel plate is much higher than those of pure titanium, and the material removal rate could reach to 36-51 m/h when the polishing speed and pressure are 100 m/s and 0.17-0.31 MPa, respectively.

scholarly journals Early Staphylococcal Biofilm Formation on Solid Orthopaedic Implant Materials: In Vitro Study

PLoS ONE ◽  
2014 ◽  
Vol 9 (10) ◽  
pp. e107588 ◽  
Author(s):  
Hironobu Koseki ◽  
Akihiko Yonekura ◽  
Takayuki Shida ◽  
Itaru Yoda ◽  
Hidehiko Horiuchi ◽  
...  
Keyword(s):  
Biofilm Formation ◽  
In Vitro Study ◽  
Vitro Study ◽  
Orthopaedic Implant ◽  
Implant Materials

Helical Rosette Nanotubes as a Potentially More Effective Orthopaedic Implant Material

2004 ◽  
Vol 845 ◽  
Author(s):  
Ai Lin Chun ◽  
Hicham Fenniri ◽  
Thomas J. Webster
Keyword(s):  
Tissue Engineering ◽  
Surface Roughness ◽  
Bone Cells ◽  
In Vitro Study ◽  
Orthopaedic Implant ◽  
Rosette Nanotubes ◽  
Osteoblast Adhesion ◽  
Organic Nanotubes ◽  
First Time

ABSTRACTOrganic nanotubes called helical rosette nanotubes (HRN) have been synthesized in this study for bone tissue engineering applications. They possess intriguing properties for various bionanotechnology applications since they can be designed to mimic the nanostructured constituent components in bone such as collagen fibers and hydroxyapatite (Ca5(PO4)3(OH)) which bone cells are naturally accustomed to interacting with. This is in contrast to currently used orthopaedic materials such as titanium which do not possess desirable nanometer surface roughness. The objective of this in vitro study was to determine bone-forming cell (osteoblasts) interactions on titanium coated with HRNs. Results of this study showed for the first time increased osteoblast adhesion on titanium coated with HRNs compared to those not coated with HRNs. In this manner, this study provided evidence that HRNs should be further considered for orthopaedic applications.

Congruent Melting Temperatures of Si-As Alloys Measured During Pulsed-Laser Melting and Rapid Solidification

1992 ◽  
Vol 279 ◽  
Author(s):  
J. A. Kittl ◽  
R. Reitano ◽  
M. J. Aziz ◽  
D. P. Brunco ◽  
M. O. Thompson
Keyword(s):  
Partition Coefficient ◽  
Temperature Measurement ◽  
Rutherford Backscattering Spectrometry ◽  
Pulsed Laser ◽  
Heat Of Fusion ◽  
Interface Temperature ◽  
Congruent Melting ◽  
Laser Melting ◽  
Time Resolved ◽  
Melting Temperatures

ABSTRACTThe solidification of Si-As alloys induced by pulsed laser melting was studied at regrowth velocities where the partition coefficient is close to unity. The congruent melting temperatures, TO, of Si-As alloys were determined using a temperature measurement technique developed for this work, and were confirmed with TOmeasurements using three other methods. The time-resolved temperature measurement uses a thin-film platinum thermistor, below and electrically isolated from the Si-As alloy layer, to directly measure the temperature during solidification. This, combined with measurements of transient conductance of the Si-As alloy, time-resolved reflectivity and Rutherford Backscattering Spectrometry, permitted the determination of the solid-liquid interface temperature, velocity and partition coefficient, the latent heat of fusion and TO for Si - 4.5 at. % As and Si - 9 at. % As alloys.

Temperature measurement within myocardium during in vitro RF catheter ablation

2000 ◽  
Vol 47 (11) ◽  
pp. 1518-1524 ◽  
Author(s):  
Hong Cao ◽  
V.R. Vorperian ◽  
Jang-Zem Tsai ◽  
S. Tungjitkusolmun ◽  
Eung Je Woo ◽  
...  
Keyword(s):  
Catheter Ablation ◽  
Temperature Measurement

scholarly journals Development of an Anti-infective Coating on the Surface of Intraosseous Implants Responsive to Enzymes and Bacteria

2021 ◽  
Author(s):  
Xin Liao ◽  
Xingfang Yu ◽  
Haiping Yu ◽  
Jiaqi Huang ◽  
Bi Zhang ◽  
...  
Keyword(s):  
Multilayer Films ◽  
Orthopaedic Implant ◽  
Inhibition Rate ◽  
Biofilm Inhibition ◽  
Bacterial Inhibition ◽  
Activity Effect ◽  
K Wires ◽  
Substrate Independent

Abstract BackgroundBacterial proliferation on the endosseous implants surface presents a new threat to the using of the bone implants. Unfortunately, there is no effective constructed antibacterial coating which is bacterial anti-adhesion substrate-independent or have long-term biofilm inhibition functions. MethodsDrug release effect was tested in CMS solution and S. aureus. We used bacterial inhibition rate assays and protein leakageexperiment to analyze the in vitro antibacterial effect of (MMT/PLL-CHX)10 multilayer film. We used the CCK-8 assay to analyze the effect of (MMT/PLL-CHX)10 multilayer films on the growth and proliferation of rat osteoblasts. Rat orthopaedic implant-related infections model was constructed to test the antimicrobial activity effect of (MMT/PLL-CHX)10 multilayer films in vivo.ResultsIn this study, the (MMT/PLL-CHX)10 multilayer films structure were progressively degraded and showed well concentration-dependent degradation characteristics following incubation with Staphylococcus aureus and CMS solution. Bacterial inhibition rate assays and protein leakageexperiment showed high levels of bactericidal activity. While the CCK-8 analysis proved that the (MMT/PLL-CHX)10 multilayer films possess perfect biocompatibility. It is somewhat encouraging that in the in vivo antibacterial tests, the K-wires coated with (MMT/PLL-CHX)10 multilayer films showed lower infections incidence and inflammation than the unmodified group, and all parameters are close to SHAM group. Conclusion(MMT/PLL-CHX)10 multilayer films provides a potential therapeutic method for orthopaedic implant-related infections.

scholarly journals A Bone-Targeting Enoxacin Delivery System to Eradicate Staphylococcus Aureus-Related Implantation Infections and Bone Loss

2021 ◽  
Vol 9 ◽  
Author(s):  
Cong Yao ◽  
Meisong Zhu ◽  
Xiuguo Han ◽  
Qiang Xu ◽  
Min Dai ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Bone Loss ◽  
Bone Tissue ◽  
Mesoporous Silica Nanoparticles ◽  
Osteoclast Differentiation ◽  
Osteoclast Formation ◽  
Bacterial Biofilm ◽  
Orthopaedic Implant

Post-operative infections in orthopaedic implants are severe complications that require urgent solutions. Although conventional antibiotics limit bacterial biofilm formation, they ignore the bone loss caused by osteoclast formation during post-operative orthopaedic implant-related infections. Fortunately, enoxacin exerts both antibacterial and osteoclast inhibitory effects, playing a role in limiting infection and preventing bone loss. However, enoxacin lacks specificity in bone tissue and low bioavailability-related adverse effects, which hinders translational practice. Here, we developed a nanosystem (Eno@MSN-D) based on enoxacin (Eno)-loaded mesoporous silica nanoparticles (MSN), decorated with the eight repeating sequences of aspartate (D-Asp8), and coated with polyethylene glycol The release results suggested that Eno@MSN-D exhibits a high sensitivity to acidic environment. Moreover, this Eno@MSN-D delivery nanosystem exhibited both antibacterial and anti-osteoclast properties in vitro. The cytotoxicity assay revealed no cytotoxicity at the low concentration (20 μg/ml) and Eno@MSN-D inhibited RANKL-induced osteoclast differentiation. Importantly, Eno@MSN-D allowed the targeted release of enoxacin in infected bone tissue. Bone morphometric analysis and histopathology assays demonstrated that Eno@MSN-D has antibacterial and antiosteoclastic effects in vivo, thereby preventing implant-related infections and bone loss. Overall, our study highlights the significance of novel biomaterials that offer new alternatives to treat and prevent orthopaedic Staphylococcus aureus-related implantation infections and bone loss.

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