Robust sequence proximity estimation by radial distance hashing

Author(s):  
M. Kertesz ◽  
Y. Yeshurun
Keyword(s):  
2020 ◽  
Vol 640 ◽  
pp. A53
Author(s):  
L. Löhnert ◽  
S. Krätschmer ◽  
A. G. Peeters

Here, we address the turbulent dynamics of the gravitational instability in accretion disks, retaining both radiative cooling and irradiation. Due to radiative cooling, the disk is unstable for all values of the Toomre parameter, and an accurate estimate of the maximum growth rate is derived analytically. A detailed study of the turbulent spectra shows a rapid decay with an azimuthal wave number stronger than ky−3, whereas the spectrum is more broad in the radial direction and shows a scaling in the range kx−3 to kx−2. The radial component of the radial velocity profile consists of a superposition of shocks of different heights, and is similar to that found in Burgers’ turbulence. Assuming saturation occurs through nonlinear wave steepening leading to shock formation, we developed a mixing-length model in which the typical length scale is related to the average radial distance between shocks. Furthermore, since the numerical simulations show that linear drive is necessary in order to sustain turbulence, we used the growth rate of the most unstable mode to estimate the typical timescale. The mixing-length model that was obtained agrees well with numerical simulations. The model gives an analytic expression for the turbulent viscosity as a function of the Toomre parameter and cooling time. It predicts that relevant values of α = 10−3 can be obtained in disks that have a Toomre parameter as high as Q ≈ 10.


2021 ◽  
Vol 5 (2) ◽  
pp. 12
Author(s):  
Matthew M. Schmitt ◽  
Daniel J. Savage ◽  
James J. Wall ◽  
John D. Yeager ◽  
Chanho Lee ◽  
...  

The US code of Federal Regulations mandates regular inspection of centrifugally cast austenitic stainless steel pipe, commonly used in primary cooling loops in light-water nuclear power plants. These pipes typically have a wall thickness of ~8 cm. Unfortunately, inspection using conventional ultrasonic techniques is not reliable as the microstructure strongly attenuates ultrasonic waves. Work is ongoing to simulate the behavior of acoustic waves in this microstructure and ultimately develop an acoustic inspection method for reactor inspections. In order to account for elastic anisotropy in the material, the texture in the steel was measured as a function of radial distance though the pipe wall. Experiments were conducted on two 10 × 12.7 × 80 mm radial sections of a cast pipe using neutron diffraction scans of 2 mm slices using the HIPPO time-of-flight neutron diffractometer at the Los Alamos Neutron Science Center (LANSCE, Los Alamos, NM, USA). Strong textures dominated by a small number of austenite grains with their (100) direction aligned in the radial direction of the pipe were observed. ODF analysis indicated that up to 70% of the probed volume was occupied by just three single-grain orientations, consistent with grain sizes of almost 1 cm. Texture and phase fraction of both ferrite and austenite phases were measured along the length of the samples. These results will inform the development of a more robust diagnostic tool for regular inspection of this material.


2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
G.J Lopes Da Cunha ◽  
B.M.L Rocha ◽  
P.N Freitas ◽  
P.M.D Lopes ◽  
A.C Santos ◽  
...  

Abstract Background Inflammation plays a pivotal role in the atherogenic process and recently has been the target of successful clinical trials. A new CT angiography method allows the identification of inflammatory pericoronary fat, which is associated with cardiovascular events. We aimed to determine whether patients with obstructive coronary artery disease (CAD) have a higher pericoronary inflammatory milieu when compared to those without CAD. Methods From a prospective CT angiography registry of patients with suspected obstructive CAD, those with a luminal stenosis >70% confirmed by invasive coronary angiography were screened (previous coronary artery bypass grafting was an exclusion criteria). Subsequently, we applied a 1:1 propensity score (PS) without replacement protocol to match obstructive CAD patients with those without CAD (non-CAD), using age, gender, BMI, hypertension, dyslipidemia, diabetes and smoking status as covariates. Similar to previous reports, pericoronary fat characterization by CT angiography was performed by analyzing the fat attenuation index (FAI) at the −30 to −190 HU range. Inflammatory fat was defined by a FAI >−70 HU. The proximal 50mm of the right coronary artery (RCA) was used to perform fat quantification and characterization. The perivascular fat was defined as the adipose tissue within a radial distance from the outer vessel wall equal to the diameter of the vessel. Results A matched cohort of 48 patients was identified (mean age 63 years; 77% males) – 24 obstructive CAD and 24 non-CAD patients. Mean FAI was numerically higher in obstructive CAD compared to the non-CAD cohort (−74±7 vs −78±7; p=0.083). Although not statistically significant, those with obstructive CAD had an increased proportion of inflammatory fat (51±10 vs 46±10%; p=0.107). After adjustment for body surface area (BSA), differences in the inflammatory fat proportion became apparent between obstructive CAD and non-CAD patients (28±6 vs 24±5%/m2; p=0.024). Furthermore, we observed a significant correlation between the inflammatory fat proportion (both absolute value and BSA adjusted) and the total number of RCA plaques (r=0.458; p=0.003; and r=0.451; p=0.003, respectively). Finally, there was 1 additional plaque observed in the RCA for each increase in 10% of proportion of inflammatory fat (p=0.018). Conclusions Perivascular coronary inflammation, as measured by FAI, seems significantly heightened in patients with obstructive CAD compared to a matched cohort of non-CAD patients. Further studies are needed to ascertain the mechanisms and possible implications of this association. Funding Acknowledgement Type of funding source: None


2021 ◽  
Vol 87 (2) ◽  
Author(s):  
Arthur Carlton-Jones ◽  
Elizabeth J. Paul ◽  
William Dorland

Coil complexity is a critical consideration in stellarator design. The traditional two-step optimization approach, in which the plasma boundary is optimized for physics properties and the coils are subsequently optimized to be consistent with this boundary, can result in plasma shapes which cannot be produced with sufficiently simple coils. To address this challenge, we propose a method to incorporate considerations of coil complexity in the optimization of the plasma boundary. Coil complexity metrics are computed from the current potential solution obtained with the REGCOIL code (Landreman, Nucl. Fusion, vol. 57, 2017, 046003). While such metrics have previously been included in derivative-free fixed-boundary optimization (Drevlak et al., Nucl. Fusion, vol. 59, 2018, 016010), we compute the local sensitivity of these metrics with respect to perturbations of the plasma boundary using the shape gradient (Landreman & Paul, Nucl. Fusion, vol. 58, 2018, 076023). We extend REGCOIL to compute derivatives of these metrics with respect to parameters describing the plasma boundary. In keeping with previous research on winding surface optimization (Paul et al., Nucl. Fusion, vol. 58, 2018, 076015), the shape derivatives are computed with a discrete adjoint method. In contrast with the previous work, derivatives are computed with respect to the plasma surface parameters rather than the winding surface parameters. To further reduce the resolution required to compute the shape gradient, we present a more efficient representation of the plasma surface which uses a single Fourier series to describe the radial distance from a coordinate axis and a spectrally condensed poloidal angle. This representation is advantageous over the standard cylindrical representation used in the VMEC code (Hirshman & Whitson, Phys. Fluids, vol. 26, 1983, pp. 3553–3568), as it provides a uniquely defined poloidal angle, eliminating a null space in the optimization of the plasma surface. In comparison with previous spectral condensation methods (Hirshman & Breslau, Phys. Plasmas, vol. 5, 1998, p. 2664), the modified poloidal angle is obtained algebraically rather than through the solution of a nonlinear optimization problem. The resulting shape gradient highlights features of the plasma boundary that are consistent with simple coils and can be used to couple coil and fixed-boundary optimization.


2021 ◽  
Vol 87 (2) ◽  
Author(s):  
P. Kim ◽  
R. Jorge ◽  
W. Dorland

A simplified analytical form of the on-axis magnetic well and Mercier's criterion for interchange instabilities for arbitrary three-dimensional magnetic field geometries is derived. For this purpose, a near-axis expansion based on a direct coordinate approach is used by expressing the toroidal magnetic flux in terms of powers of the radial distance to the magnetic axis. For the first time, the magnetic well and Mercier's criterion are then written as a one-dimensional integral with respect to the axis arclength. When compared with the original work of Mercier, the derivation here is presented using modern notation and in a more streamlined manner that highlights essential steps. Finally, these expressions are verified numerically using several quasisymmetric and non-quasisymmetric stellarator configurations including Wendelstein 7-X.


2015 ◽  
Vol 08 (04) ◽  
pp. 1550012 ◽  
Author(s):  
Qinqin Zhang ◽  
Maureen Neitz ◽  
Jay Neitz ◽  
Ruikang K. Wang

Purpose: To provide a geographical map of choroidal thickness (CT) around the macular region among subjects with low, moderate and high myopia. Methods: 20 myopic subjects (n = 40 eyes) without other identified pathologies participated in this study: 20 eyes of ≤ 3 diopters (D) (low myopic), 10 eyes between -3 and -6D (moderate myopic), and 10 eyes of ≥ 6D (high myopic). The mean age of subjects was 30.2 years (± 7.6 years; range, 24 to 46 years). A 1050 nm spectral-domain optical coherence tomography (SD-OCT) system, operating at 120 kHz imaging rate, was used in this study to simultaneously capture 3D anatomical images of the choroid and measure intraocular length (IOL) in the subject. The 3D OCT images of the choroid were segmented into superior, inferior, nasal and temporal quadrants, from which the CT was measured, representing radial distance between the outer retinal pigment epithelium (RPE) layer and inner scleral border. Measurements were made within concentric regions centered at fovea centralis, extended to 5 mm away from fovea at 1 mm intervals in the nasal and temporal directions. The measured IOL was the distance from the anterior cornea surface to the RPE in alignment along the optical axis of the eye. Statistical analysis was performed to evaluate CT at each geographic region and observe the relationship between CT and the degree of myopia. Results: For low myopic eyes, the IOL was measured at 24.619 ± 0.016 mm. The CT (273.85 ± 49.01 μm) was greatest under fovea as is in the case of healthy eyes. Peripheral to the fovea, the mean CT decreased rapidly along the nasal direction, reaching a minimum of 180.65 ± 58.25μm at 5 mm away from the fovea. There was less of a change in thickness from the fovea in the temporal direction reaching a minimum of 234.25 ± 42.27 μm. In contrast to the low myopic eyes, for moderate and high myopic eyes, CTs were thickest in temporal region (where CT = 194.94 ± 27.28 and 163 ± 34.89 μm, respectively). Like the low myopic eyes, moderate and high myopic eyes had thinnest CTs in the nasal region (where CT = 100.84 ± 16.75 and 86.64 ± 42.6μm, respectively). High myopic eyes had the longest mean IOL (25.983 ± 0.021mm), while the IOL of moderate myopia was 25.413 ± 0.022 mm (**p < 0.001). The CT reduction rate was calculated at 31.28 μm/D (diopter) from low to moderate myopia, whilst it is 13.49 μm/D from moderate to high myopia. The similar tendency was found for the IOL reduction rate in our study: 0.265 mm/D from low to moderate myopia, and 0.137 mm/D from moderate to high myopia. Conclusion: The CT decreases and the IOL increases gradually with the increase of myopic condition. The current results support the theory that choroidal abnormality may play an important role in the pathogenesis of myopic degeneration.


2019 ◽  
Vol 76 (10) ◽  
pp. 3267-3283 ◽  
Author(s):  
Cheng-Ku Yu ◽  
Che-Yu Lin ◽  
Jhang-Shuo Luo

Abstract This study used radar and surface observations to track a long-lasting outer tropical cyclone rainband (TCR) of Typhoon Jangmi (2008) over a considerable period of time (~10 h) from its formative to mature stage. Detailed analyses of these unique observations indicate that the TCR was initiated on the eastern side of the typhoon at a radial distance of ~190 km as it detached from the upwind segment of a stratiform rainband located close to the inner-core boundary. The outer rainband, as it propagated cyclonically outward, underwent a prominent convective transformation from generally stratiform precipitation during the earlier period to highly organized, convective precipitation during its mature stage. The transformation was accompanied by a clear trend of surface kinematics and thermodynamics toward squall-line-like features. The observed intensification of the rainband was not simply related to the spatial variation of the ambient CAPE or potential instability; instead, the dynamical interaction between the prerainband vertical shear and cold pools, with progression toward increasingly optimal conditions over time, provides a reasonable explanation for the temporal alternation of the precipitation intensity. The increasing intensity of cold pools was suggested to play an essential role in the convective transformation for the rainband. The propagation characteristics of the studied TCR were distinctly different from those of wave disturbances frequently documented within the cores of tropical cyclones; however, they were consistent with the theoretically predicted propagation of convectively generated cold pools. The convective transformation, as documented in the present case, is anticipated to be one of the fundamental processes determining the evolving and structural nature of outer TCRs.


Author(s):  
Clifford A. Brown

Many configurations proposed for the next generation of aircraft rely on the wing or other aircraft surfaces to shield the engine noise from the observers on the ground. However, the ability to predict the shielding effect and any new noise sources that arise from the high-speed jet flow interacting with a hard surface is currently limited. Furthermore, quality experimental data from jets with surfaces nearby suitable for developing and validating noise prediction methods are usually tied to a particular vehicle concept and, therefore, very complicated. The Jet-Surface Interaction Tests are intended to supply a high quality set of data covering a wide range of surface geometries and positions and jet flows to researchers developing aircraft noise prediction tools. The initial goal is to measure the noise of a jet near a simple planar surface while varying the surface length and location in order to: (1) validate noise prediction schemes when the surface is acting only as a jet noise shield and when the jet-surface interaction is creating additional noise, and (2) determine regions of interest for future, more detailed, tests. To meet these objectives, a flat plate was mounted on a two-axis traverse in two distinct configurations: (1) as a shield between the jet and the observer and (2) as a reflecting surface on the opposite side of the jet from the observer. The surface length was varied between 2 and 20 jet diameters downstream of the nozzle exit. Similarly, the radial distance from the jet centerline to the surface face was varied between 1 and 16 jet diameters. Far-field and phased array noise data were acquired at each combination of surface length and radial location using two nozzles operating at jet exit conditions across several flow regimes: subsonic cold, subsonic hot, underexpanded, ideally expanded, and overexpanded supersonic. The far-field noise results, discussed here, show where the jet noise is partially shielded by the surface and where jet-surface interaction noise dominates the low frequency spectrum as a surface extends downstream and approaches the jet plume.


1965 ◽  
Vol 87 (4) ◽  
pp. 355-360 ◽  
Author(s):  
J. C. Chato

The general problem of condensation in a variable acceleration field was investigated analytically. The case of the linear variation, which occurs in a constant cross section, rotating thermosyphon, was treated in detail. The results show that the condensate thickness and Nusselt numbers approach limiting values as the radial distance increases. The effects of the temperature differential and the Prandtl number are similar to those in other condensation problems; i.e., the heat transfer increases slightly with increasing temperature differential if Pr > 1, but it decreases with increasing temperature differential if Pr ≪ 1.


2003 ◽  
Vol 36 (4) ◽  
pp. 1069-1074 ◽  
Author(s):  
D. Eberbeck ◽  
A. Lange ◽  
M. Hentschel

Different very dilute suspensions of magnetic nanoparticles (magnetite surrounded by an organic shell) in water (ferrofluids) were investigated using small-angle X-ray scattering. It is shown that the scattering originates not only from noncorrelated core–shell nanoparticles, but also from larger structures. By modelling, these structures can be identified as close-packed clusters consisting of core–shell particles (core diameter ∼10 nm). The analysis of the radial distance distribution function, obtained by Fourier transformation of the scattered intensity, reveals a lower bound of the mean cluster size of about 40 nm. The formation of clusters is persistent, even in very dilute suspensions.


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