The Periodic Cellular Behaviors Under the Physical Effects of Plasma Medicine

2021 ◽  
Author(s):  
Li Lin ◽  
Dayun Yan ◽  
Luis Martinez ◽  
Yi Liu ◽  
Michael Keidar
Keyword(s):  
Plasma Medicine ◽  
Cellular Behaviors ◽  
Physical Effects

Modeling Vibration-Induced Tire-Pavement Interaction Noise in the Mid-frequency Range

2020 ◽  
Author(s):  
Sterling McBride ◽  
Ricardo Burdisso ◽  
Corina Sandu
Keyword(s):  
Sound Intensity ◽  
Element Model ◽  
Dominant Frequency ◽  
Contact Forces ◽  
Surface Velocity ◽  
New Wave ◽  
Normal Surface ◽  
Radiated Noise ◽  
Physical Effects ◽  
Effects Of Rotation

ABSTRACT Tire-pavement interaction noise (TPIN) is one of the main sources of exterior noise produced by vehicles traveling at greater than 50 kph. The dominant frequency content is typically within 500–1500 Hz. Structural tire vibrations are among the principal TPIN mechanisms. In this work, the structure of the tire is modeled and a new wave propagation solution to find its response is proposed. Multiple physical effects are accounted for in the formulation. In an effort to analyze the effects of curvature, a flat plate and a cylindrical shell model are presented. Orthotropic and nonuniform structural properties along the tire's transversal direction are included to account for differences between its sidewalls and belt. Finally, the effects of rotation and inflation pressure are also included in the formulation. Modeled frequency response functions are analyzed and validated. In addition, a new frequency-domain formulation is presented for the computation of input tread pattern contact forces. Finally, the rolling tire's normal surface velocity response is coupled with a boundary element model to demonstrate the radiated noise at the leading and trailing edge locations. These results are then compared with experimental data measured with an on-board sound intensity system.

NUMERICAL STUDY OF DETONATION PROPAGATION IN VISCOUS TURBULENT FLOW IN A DUCT

2020 ◽  
Author(s):  
V. A. SABELNIKOV ◽  
◽  
V. V. VLASENKO ◽  
S. BAKHNE ◽  
S. S. MOLEV ◽  
...  
Keyword(s):  
Complex Geometry ◽  
Numerical Study ◽  
Navier Stokes ◽  
Detonation Waves ◽  
Detonation Propagation ◽  
Eddy Simulation ◽  
Detonation Structure ◽  
Classical Studies ◽  
Large Eddy ◽  
Physical Effects

Gasdynamics of detonation waves was widely studied within last hundred years - analytically, experimentally, and numerically. The majority of classical studies of the XX century were concentrated on inviscid aspects of detonation structure and propagation. There was a widespread opinion that detonation is such a fast phenomenon that viscous e¨ects should have insigni¦cant in§uence on its propagation. When the era of calculations based on the Reynolds-averaged Navier- Stokes (RANS) and large eddy simulation approaches came into effect, researchers pounced on practical problems with complex geometry and with the interaction of many physical effects. There is only a limited number of works studying the in§uence of viscosity on detonation propagation in supersonic §ows in ducts (i. e., in the presence of boundary layers).

scholarly journals Micro RNAs in Regulation of Cellular Redox Homeostasis

2021 ◽  
Vol 22 (11) ◽  
pp. 6022
Author(s):  
Sylwia Ciesielska ◽  
Izabella Slezak-Prochazka ◽  
Patryk Bil ◽  
Joanna Rzeszowska-Wolny
Keyword(s):  
Target Genes ◽  
Redox Homeostasis ◽  
Messenger Rnas ◽  
Cellular Redox ◽  
Cell Responses ◽  
Regulatory Circuits ◽  
Micro Rnas ◽  
Cellular Behaviors ◽  
Homeostasis Regulation ◽  
Thioredoxin Reductases

In living cells Reactive Oxygen Species (ROS) participate in intra- and inter-cellular signaling and all cells contain specific systems that guard redox homeostasis. These systems contain both enzymes which may produce ROS such as NADPH-dependent and other oxidases or nitric oxide synthases, and ROS-neutralizing enzymes such as catalase, peroxiredoxins, thioredoxins, thioredoxin reductases, glutathione reductases, and many others. Most of the genes coding for these enzymes contain sequences targeted by micro RNAs (miRNAs), which are components of RNA-induced silencing complexes and play important roles in inhibiting translation of their targeted messenger RNAs (mRNAs). In this review we describe miRNAs that directly target and can influence enzymes responsible for scavenging of ROS and their possible role in cellular redox homeostasis. Regulation of antioxidant enzymes aims to adjust cells to survive in unstable oxidative environments; however, sometimes seemingly paradoxical phenomena appear where oxidative stress induces an increase in the levels of miRNAs which target genes which are supposed to neutralize ROS and therefore would be expected to decrease antioxidant levels. Here we show examples of such cellular behaviors and discuss the possible roles of miRNAs in redox regulatory circuits and further cell responses to stress.

scholarly journals Possible Pitfalls in the Analysis of Minerals and Loose Materials by Portable XRF, and How to Overcome Them

Minerals ◽  
2020 ◽  
Vol 11 (1) ◽  
pp. 33
Author(s):  
Valérie Laperche ◽  
Bruno Lemière
Keyword(s):  
Fluorescence Spectroscopy ◽  
Laboratory Data ◽  
Data Sets ◽  
Light Elements ◽  
Portable Xrf ◽  
X Ray ◽  
Protective Films ◽  
The Matrix ◽  
Valuable Complement ◽  
Physical Effects

Portable X-ray fluorescence spectroscopy is now widely used in almost any field of geoscience. Handheld XRF analysers are easy to use, and results are available in almost real time anywhere. However, the results do not always match laboratory analyses, and this may deter users. Rather than analytical issues, the bias often results from sample preparation differences. Instrument setup and analysis conditions need to be fully understood to avoid reporting erroneous results. The technique’s limitations must be kept in mind. We describe a number of issues and potential pitfalls observed from our experience and described in the literature. This includes the analytical mode and parameters; protective films; sample geometry and density, especially for light elements; analytical interferences between elements; physical effects of the matrix and sample condition, and more. Nevertheless, portable X-ray fluorescence spectroscopy (pXRF) results gathered with sufficient care by experienced users are both precise and reliable, if not fully accurate, and they can constitute robust data sets. Rather than being a substitute for laboratory analyses, pXRF measurements are a valuable complement to those. pXRF improves the quality and relevance of laboratory data sets.

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