A Neighbor Immunization Strategy to Block Virus Spreading on Networks

Author(s):  
Hao Yaohui ◽  
Liu Yingze ◽  
Zhao Baole ◽  
Wang Qingxian
2007 ◽  
Vol 12 (02) ◽  
Author(s):  
A. Terceño Gómez ◽  
A. Fernández Bariviera ◽  
J. M. Brotons Martí­nez

Author(s):  
Ira Patriani

Border areas, is one of affected area on COVID_19 this present. Many of people cn not go out as usually, adding almost each country has to implement their territorial limitation (lockdown policy) to minimalize this virus spreading. One of Malaysia State, where very close and get direct border with Indonesia. This research took place at Sanggau District, Entikong, Gun Tembawang Village.The research approach used is qualitative, using data collection methods in the form of interviews, observations, and documentation supported by interviews with the theoretical approach to the negative and positive aspects on policy implementation. Research results, The results stated that the lockdown activities of Malaysia which were affected by the corona virus outbreak needed to be carried out in an effort to minimize the spread of the virus outbreak. Although of course it has a negative impact on the country's economic structure, social issues and other sector. In implementing this lockdown, there is a need for cooperation between the government and the community as well as an agreement with neighboring countries in terms of the mobility of residents closest to each other's territory on exemptions in order to realize social welfare and public health without limiting the origin of the state, religion, community and profession. Especially in border areas where mobility and kinship ties have always been closer than in other regions. Keywords: Border area, lockdown policy, covid_19


2010 ◽  
Vol 30 (7) ◽  
pp. 1775-1777
Author(s):  
Peng JI ◽  
Hong-wei GE

2021 ◽  
Vol 28 (1) ◽  
Author(s):  
Pei-Shan Sung ◽  
Shie-Liang Hsieh

AbstractDysregulated formation of neutrophil extracellular traps (NETs) is observed in acute viral infections. Moreover, NETs contribute to the pathogenesis of acute viral infections, including those caused by the dengue virus (DV) and severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Furthermore, excessive NET formation (NETosis) is associated with disease severity in patients suffering from SARS-CoV-2-induced multiple organ injuries. Dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN) and other members of C-type lectin family (L-SIGN, LSECtin, CLEC10A) have been reported to interact with viral glycans to facilitate virus spreading and exacerbates inflammatory reactions. Moreover, spleen tyrosine kinase (Syk)-coupled C-type lectin member 5A (CLEC5A) has been shown as the pattern recognition receptor for members of flaviviruses, and is responsible for DV-induced cytokine storm and Japanese encephalomyelitis virus (JEV)-induced neuronal inflammation. Moreover, DV activates platelets via CLEC2 to release extracellular vesicles (EVs), including microvesicles (MVs) and exosomes (EXOs). The DV-activated EXOs (DV-EXOs) and MVs (DV-MVs) stimulate CLEC5A and Toll-like receptor 2 (TLR2), respectively, to enhance NET formation and inflammatory reactions. Thus, EVs from virus-activated platelets (PLT-EVs) are potent endogenous danger signals, and blockade of C-type lectins is a promising strategy to attenuate virus-induced NETosis and intravascular coagulopathy.


2021 ◽  
Vol 13 (3) ◽  
pp. 1110
Author(s):  
Olga Semenova ◽  
Julia Apalkova ◽  
Marina Butovskaya

Despite the enforced lockdown regime in late March 2020 in Russia, the phenomenon of the continued virus spreading highlighted the importance of studies investigating the range of biosocial attributes and spectrum of individual motivations underlying the permanent presence of the substantial level of spatial activity. For this matter, we conducted a set of surveys between March and June 2020 (N = 492). We found that an individual’s health attitude is the most consistent factor explaining mobility differences. However, our data suggested that wariness largely determines adequate health attitudes; hence, a higher level of wariness indirectly reduced individual mobility. Comparative analysis revealed the critical biosocial differences between the two sexes, potentially rooted in the human evolutionary past. Females were predisposed to express more wariness in the face of new environmental risks; therefore, they minimize their mobility and outdoor contacts. In contrast to them, the general level of spatial activity reported by males was significantly higher. Wariness in the males’ sample was less associated with the novel virus threat, but to a great extent, it was predicted by the potential economic losses variable. These findings correspond to the evolutionary predictions of sexual specialization and the division of family roles.


Sign in / Sign up

Export Citation Format

Share Document