Measurement Of Strain And Strain Rate Developed By Jumping Exercised In Vivo in Humans

Author(s):  
C. Milgrom ◽  
A. Finestone ◽  
N. Benjoya ◽  
A. Simkin ◽  
I. Ekenman ◽  
...  
2019 ◽  
Vol 19 (3) ◽  
pp. 1109-1130 ◽  
Author(s):  
Marzieh Hajiaghamemar ◽  
Taotao Wu ◽  
Matthew B. Panzer ◽  
Susan S. Margulies

AbstractWith the growing rate of traumatic brain injury (TBI), there is an increasing interest in validated tools to predict and prevent brain injuries. Finite element models (FEM) are valuable tools to estimate tissue responses, predict probability of TBI, and guide the development of safety equipment. In this study, we developed and validated an anisotropic pig brain multi-scale FEM by explicitly embedding the axonal tract structures and utilized the model to simulate experimental TBI in piglets undergoing dynamic head rotations. Binary logistic regression, survival analysis with Weibull distribution, and receiver operating characteristic curve analysis, coupled with repeated k-fold cross-validation technique, were used to examine 12 FEM-derived metrics related to axonal/brain tissue strain and strain rate for predicting the presence or absence of traumatic axonal injury (TAI). All 12 metrics performed well in predicting of TAI with prediction accuracy rate of 73–90%. The axonal-based metrics outperformed their rival brain tissue-based metrics in predicting TAI. The best predictors of TAI were maximum axonal strain times strain rate (MASxSR) and its corresponding optimal fraction-based metric (AF-MASxSR7.5) that represents the fraction of axonal fibers exceeding MASxSR of 7.5 s−1. The thresholds compare favorably with tissue tolerances found in in–vitro/in–vivo measurements in the literature. In addition, the damaged volume fractions (DVF) predicted using the axonal-based metrics, especially MASxSR (DVF = 0.05–4.5%), were closer to the actual DVF obtained from histopathology (AIV = 0.02–1.65%) in comparison with the DVF predicted using the brain-related metrics (DVF = 0.11–41.2%). The methods and the results from this study can be used to improve model prediction of TBI in humans.


2021 ◽  
Author(s):  
Chenxi Yan ◽  
Stuart Warden ◽  
Mariana E Kersh

The tibia is a common site for stress fractures, which are believed to develop from microdamage accumulation to repetitive sub-yield strains. There is a need to understand how the tibia is loaded in vivo to understand how stress fractures develop and design exercises to build a more robust bone. Here, we use subject-specific, muscle-driven, finite element simulations of 11 basketball players to calculate strain and strain rate distributions at the midshaft and distal tibia during six activities: walking, sprinting, lateral cut, jumping after landing, changing direction from forward-to-backward sprinting, and changing direction while side shuffling. Maximum compressive strains were at least double maximum tensile microstrains (mu) during the stance phase of all activities. Sprinting and lateral cut had the highest compressive (-2773 +/- 934 mu and -2266 +/- 815 mu, respectively) and tensile (999 +/- 381 mu and 907 +/- 261 mu, respectively) strains. These activities also had the highest strains rates (peak compressive strain rate = 46237 +/- 38217 mu/s and 41510 +/- 17245 mu/s, respectively). Compressive strains principally occurred in the posterior tibia for all activities; however, tensile strain location varied. In particular, activities involving a change in direction increased tensile loads in the anterior tibia. These observations may guide preventative and management strategies for tibial stress fractures. In terms of prevention, the strain distributions suggest individuals should perform activities involving changes in direction during growth to adapt different parts of the tibia and develop a more fatigue resistant bone. In terms of management, the greater strain and strain rates during sprinting than jumping suggests jumping activities may be commenced earlier than full pace running. The greater anterior tensile strains during changes in direction suggest introduction of these types of activities should be delayed during recovery from an anterior tibial stress fractures, which have a high-risk of healing complications.


2021 ◽  
Author(s):  
Chenxi Yan ◽  
Stuart Warden ◽  
Mariana E Kersh

The tibia is a common site for stress fractures, which are believed to develop from microdamage accumulation to repetitive sub-yield strains. There is a need to understand how the tibia is loaded in vivo to understand how stress fractures develop and design exercises to build a more robust bone. Here, we use subject-specific, muscle-driven, finite element simulations of 11 basketball players to calculate strain and strain rate distributions at the midshaft and distal tibia during six activities: walking, sprinting, lateral cut, jumping after landing, changing direction from forward-to-backward sprinting, and changing direction while side shuffling. Maximum compressive strains were at least double maximum tensile microstrains (mu) during the stance phase of all activities. Sprinting and lateral cut had the highest compressive (-2773 +/- 934 mu) and -2266 +/-815 mu, respectively) and tensile (999 +/- 381 mu and 907 +/- 261 mu, respectively) strains. These activities also had the highest strains rates (peak compressive strain rate = 46237 +/- 38217 mu/s and 41510 +/- 17245 mu/s, respectively). Compressive strains principally occurred in the posterior tibia for all activities; however, tensile strain location varied. In particular, activities involving a change in direction increased tensile loads in the anterior tibia. These observations may guide preventative and management strategies for tibial stress fractures. In terms of prevention, the strain distributions suggest individuals should perform activities involving changes in direction during growth to adapt different parts of the tibia and develop a more fatigue resistant bone. In terms of management, the greater strain and strain rates during sprinting than jumping suggests jumping activities may be commenced earlier than full pace running. The greater anterior tensile strains during changes in direction suggest introduction of these types of activities should be delayed during recovery from an anterior tibial stress fractures, which have a high-risk of healing complications.


Author(s):  
M. F. Stevens ◽  
P. S. Follansbee

The strain rate sensitivity of a variety of materials is known to increase rapidly at strain rates exceeding ∼103 sec-1. This transition has most often in the past been attributed to a transition from thermally activated guide to viscous drag control. An important condition for imposition of dislocation drag effects is that the applied stress, σ, must be on the order of or greater than the threshold stress, which is the flow stress at OK. From Fig. 1, it can be seen for OFE Cu that the ratio of the applied stress to threshold stress remains constant even at strain rates as high as 104 sec-1 suggesting that there is not a mechanism transition but that the intrinsic strength is increasing, since the threshold strength is a mechanical measure of intrinsic strength. These measurements were made at constant strain levels of 0.2, wnich is not a guarantee of constant microstructure. The increase in threshold stress at higher strain rates is a strong indication that the microstructural evolution is a function of strain rate and that the dependence becomes stronger at high strain rates.


Materials ◽  
2021 ◽  
Vol 14 (8) ◽  
pp. 2021
Author(s):  
Oleksandr Lypchanskyi ◽  
Tomasz Śleboda ◽  
Aneta Łukaszek-Sołek ◽  
Krystian Zyguła ◽  
Marek Wojtaszek

The flow behavior of metastable β titanium alloy was investigated basing on isothermal hot compression tests performed on Gleeble 3800 thermomechanical simulator at near and above β transus temperatures. The flow stress curves were obtained for deformation temperature range of 800–1100 °C and strain rate range of 0.01–100 s−1. The strain compensated constitutive model was developed using the Arrhenius-type equation. The high correlation coefficient (R) as well as low average absolute relative error (AARE) between the experimental and the calculated data confirmed a high accuracy of the developed model. The dynamic material modeling in combination with the Prasad stability criterion made it possible to generate processing maps for the investigated processing temperature, strain and strain rate ranges. The high material flow stability under investigated deformation conditions was revealed. The microstructural analysis provided additional information regarding the flow behavior and predominant deformation mechanism. It was found that dynamic recovery (DRV) was the main mechanism operating during the deformation of the investigated β titanium alloy.


1982 ◽  
Vol 104 (1) ◽  
pp. 41-46
Author(s):  
T. C. Hsu ◽  
I. M. Bidhendi

A superplastic Zn-Al alloy in sheet form is formed into a bulge over a circular hole by pneumatic pressure. The geometry, the stress, the strain, and the strain-rate are determined at various points covering the whole specimen and at various stages of the forming process. The complicated shape, and its complicated changes, are represented by introducing an index for the local geometry, called “prolateness,” which is also related to the local stress ratio in a simple way. The biaxial stress is analyzed into a strain-proportional and a strain-rate-proportional component, which represent, respectively, the quasi-solid and the quasi-liquid behavior of the superplastic material.


2012 ◽  
Vol 535-537 ◽  
pp. 633-638 ◽  
Author(s):  
Zheng Hai Zhu ◽  
Sheng Tao Qiu

It was analyzed by strain-induced precipitation model that Nb(C,N) precipitation in micro alloy steel slab was effected by strain rate during continuous casting process. The results are as follows: The changing of casting speed could effect the time for 5%precipitation of Nb(C,N), which was decreasing with increasing casting speed at certain temperature and strain rate. Slab strain and strain rate were too small in bending zone and leveling zone. The effect of slab strain rate on Nb(C,N) precipitation could be ignore when Nb(C,N) precipitation in continuous casting process was studied.


Sign in / Sign up

Export Citation Format

Share Document