Novel Paradigm of Subdural Cortical Stimulation Does Not Cause Thermal Damage in Brain Tissue: A Simulation-Based Study

Author(s):  
J. Vrba ◽  
R. Janca ◽  
M. Blaha ◽  
P. Krsek ◽  
D. Vrba
2018 ◽  
Vol 63 (5) ◽  
pp. 587-594
Author(s):  
Martin Oelschlägel ◽  
Tobias Meyer ◽  
Gabriele Schackert ◽  
Matthias Kirsch ◽  
Stephan B. Sobottka ◽  
...  

AbstractBrain tumor resection is even today one of the most challenging disciplines in neurosurgery. The current state of the art for the identification of tumor tissue during the surgical procedure comprises a wide variety of different tools, each with its own limitations and drawbacks. In this paper, we present a novel approach, the use of optical imaging in connection with direct electrical cortical stimulation (DCS), for identification of impaired tumor tissue and functional intact normal brain tissue under intraoperative conditions. Measurements with an optical imaging setup were performed as a proof of concept on three patients who underwent tumor resection of superficial gliomas. Direct electrical stimulations were applied on tumor tissue and surrounding brain tissue in each patient and characteristic features from the observed changes in the optical properties were compared between the different groups. The results reveal that in all patients a differentiation between non-functional tumor tissue and functional intact brain tissue was possible, and the technique might be a useful clinical tool in the future.


1997 ◽  
Vol 12 (1) ◽  
pp. 21-30 ◽  
Author(s):  
R. Cubeddu ◽  
C. Sozzi ◽  
P. Taroni ◽  
G. Valentini ◽  
G. Bottiroli ◽  
...  

Author(s):  
Can Kerse ◽  
Seydi Yavas ◽  
Hamit Kalaycioglu ◽  
Mehmet D. Asik ◽  
Onder Akcaalan ◽  
...  

1994 ◽  
Vol 34 (4) ◽  
pp. 209-215 ◽  
Author(s):  
Nobuhiko MATSUMI ◽  
Kengo MATSUMOTO ◽  
Nobuya MISHIMA ◽  
Eiji MORIYAMA ◽  
Tomohisa FURUTA ◽  
...  

2007 ◽  
Vol 1 (4) ◽  
pp. 293-296 ◽  
Author(s):  
Calvin C. Silverstein

In a self-cooled drill, an especially designed bur is used to transport heat generated at the cutting edge into the handpiece, where it is dissipated into an air heat sink. The bur contains a sealed cavity partially filled with water, which transports heat via the principle of rotating heat pipe technology. The heat transport capability of burs fitted out as rotating heat pipes was established. A conceptual design for a representative bur was prepared, based on surgical drill sculpting criteria. It appears that a self-cooled surgical drill for sculpting can limit bone temperatures below levels for the initiation of thermal damage in bone, nerve, and brain tissue, without the need to employ an externally applied coolant.


2012 ◽  
Vol 13 (4) ◽  
pp. 284-293
Author(s):  
Egidijus Rytas Vaidogas ◽  
Lina Kisežauskienė

An assessment of risk posed by a road transportation of liquefied gases to roadside property is considered. The attention is focussed on an estimation of the probability of thermal damage to a roadside object. Such damage can be caused by a boiling-liquid expanding-vapour explosion (BLEVE) of a road tank. It is suggested to estimate this probability by a combined application of stochastic simulation and deterministic models used to predict a thermal effect of a BLEVE fireball. A development of a fragility function expressing the probability of ignition of the roadside object is discussed. The fragility function is integrated into the simulation-based procedure of an estimation of the thermal damage probability. The approach proposed in this study is illustrated by an example which considers an assessment of thermal damage to a reservoir built in the vicinity of a road used for transportation of liquefied gases.


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