Cross-Contamination Control at MIT's Microsystems Technology Labs

Author(s):  
Vicky Diadiuk
Nutrients ◽  
2018 ◽  
Vol 10 (9) ◽  
pp. 1274 ◽  
Author(s):  
Priscila Farage ◽  
Renata Puppin Zandonadi ◽  
Verônica Cortez Ginani ◽  
Lenora Gandolfi ◽  
Eduardo Yoshio Nakano ◽  
...  

Gluten cross-contamination in gluten-free food may jeopardize treatment of celiac patients. Considering the deficit of appropriate instruments to enable the implementation of safe production practices for gluten-free food, this study aimed to evaluate the application of a check-list elaborated for gluten cross-contamination prevention in food services. The instrument was applied in 60 Brazilian food services. Interobserver reproducibility and internal consistency of the check-list were tested. A score classification was created for establishments according to the food contamination risk assessment. Subsequent to the application and statistical analysis, the original instrument was reduced to a 30-item check-list. In the reproducibility analysis, none of the 30 items showed significant divergence among the evaluators (p > 0.05 in the Cochran Q test). The 30-item version of the check-list presented Kuder–Richardson Formula 20 (KR-20) = 0.771, indicating good internal consistency. The proposed classification score is obtained by adding 1 point for each item with an “adequate” response; therefore, the final score may vary between 0 and 30 points. Establishments with up to 15 points exhibit risk of gluten contamination, while establishments with a score above 16 points exhibit low risk of contamination. The check-list displayed good reproducibility and internal consistency, suggesting that it could be a useful gluten contamination control instrument in food services.


2021 ◽  
Vol 13 (21) ◽  
pp. 12123
Author(s):  
Aleksandra Bogdanowicz ◽  
Monika Zubrowska-Sudol ◽  
Andrzej Krasinski ◽  
Miroslaw Sudol

Research conducted so far on the presence of microplastics in the environment shows that these items are ubiquitous pollutants and therefore constitute an inherent part of our lives. This constitutes a significant problem in many aspects, and one of them is the correct identification of microplastics in environmental samples. Environmental samples can be easily contaminated by plastic microparticles from other sources if proper precautions are not taken during sampling and analysis. The consequence of not taking this cross-contamination into account when analysing the results may be their significant overestimation. This review aims to draw attention to the problem of cross-contamination that accompanies the collection and analysis of samples for the presence of microplastics, and to discuss this issue in a comprehensive manner. The article indicates potential sources of cross-contamination, lists the mitigation methods, and describes the possibilities of assessing this type of contamination. Moreover, the review examines how cross-contamination control appears in practice, based on the available literature data.


2003 ◽  
Vol 17 (3) ◽  
pp. 254-260 ◽  
Author(s):  
Leonardo Eloy Rodrigues Filho ◽  
Antonio Muench ◽  
Carlos Francci ◽  
Angelika Katia Luebke ◽  
Andréia Aparecida Traina

The handling of vinyl polysiloxane (addition silicone) impression putties with latex gloves is said to interfere with the setting of these impression materials. The aim of this study is to evaluate the effect of handling techniques on the setting of vinyl polysiloxane impression putties using several types of gloves. The setting of these materials was evaluated by means of an elasticimeter. Four vinyl polysiloxane putty impression materials and five brands of gloves (one made of vinyl, one of synthetic rubber, and three of natural rubber) were studied. Based on the type of glove, they were previously washed or not, and a spatula was used or not for initial mixing (before handmixing). The vinyl, the synthetic and one of the natural rubber gloves did not require the previous washing procedure and/or the use of a spatula for initial mixing. Two other natural rubber gloves - depending on the silicone -, showed satisfactory results only when the initial mixing was performed with a spatula. It was concluded that setting inhibition depends on the kind of vinyl polysiloxane impression material and the kind of gloves used, but when the initial mixing was performed with the spatula this setting inhibition was overcome. The results of this study also showed that it is possible to associate cross-contamination control and satisfactory performance of addition silicone putty materials. When doubts arise from the compatibility between vinyl polysiloxane impression putties and gloves, the initial mixing should be performed with a spatula.


2020 ◽  
Vol 400 ◽  
pp. 109-116
Author(s):  
P. González-Aguirre ◽  
Minh Phuong Tran ◽  
Fernando Herrán ◽  
Sung In Moon ◽  
Jorgen Lundgren ◽  
...  

Sorption and outgassing mechanisms of corrosive gases in relation with wafers lost yield due to polymer container Front Opening Unified Pod (FOUP), is crucial information to understand the cross contamination between FOUP and wafers. This occurs when FOUPs (made in polymers) outgas contaminants into the wafer surrounding minienvironment. Gas sorption is governed by surface adsorption, followed by diffusion and solubility and then, permeability appears as a key parameter to understanding these cross contamination phenomena. In this work, we present the transport coefficients obtained for gaseous HF and HCl at cleanroom conditions (Patm, 21 ± 2°C & 40% RH) at two different HX concentrations using the sorption kinetic method, based on Fick’s law, for thin films (≈50μm) of PEI. Finally, we establish the relationship between the sorption parameters of a polymer thin film and the potential contamination transfer from a FOUP whose main polymer material is similar.


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