scholarly journals Can CT imaging features of ground-glass opacity predict invasiveness? A meta-analysis

2018 ◽  
Vol 9 (4) ◽  
pp. 452-458 ◽  
Author(s):  
Jian Dai ◽  
Guoyou Yu ◽  
Jianqiang Yu
Keyword(s):  
Meta Analysis ◽  
Ground Glass Opacity ◽  
Ct Imaging ◽  
Ground Glass ◽  
Imaging Features

scholarly journals Early CT features of COVID-19 pneumonia, association with patients’ age and duration of presenting complaint

2021 ◽  
Vol 52 (1) ◽  
Author(s):  
Reem M. EL Kady ◽  
Hosam A. Hassan ◽  
Tareef S. Daqqaq ◽  
Rania Makboul ◽  
Hanan Mosleh Ibrahim
Keyword(s):  
Pleural Effusion ◽  
Ground Glass Opacity ◽  
Ct Imaging ◽  
Older Age ◽  
Ground Glass ◽  
Imaging Features ◽  
Age Group ◽  
Patient Age ◽  
Atypical Features ◽  
Patient Âgé

Abstract Background Coronavirus disease (COVID-19) is a respiratory syndrome with a variable degree of severity. Imaging is a vital component of disease monitoring and follow-up in coronavirus pulmonary syndromes. The study of temporal changes of CT findings of COVID-19 pneumonia can help in better understanding of disease pathogenesis and prediction of disease prognosis. In this study, we aim to determine the typical and atypical CT imaging features of COVID-19 and discuss the association of typical CT imaging features with the duration of the presenting complaint and patients’ age. Results The lesions showed unilateral distribution in 20% of cases and bilateral distribution in 80% of cases. The lesions involved the lower lung lobes in 30% of cases and showed diffuse involvement in 58.2% of cases. The lesions showed peripheral distribution in 74.5% of cases. The most common pattern was multifocal ground glass opacity found in 72.7% of cases. Atypical features like cavitation and pleural effusion can occur early in the disease course. There was significant association between increased number of the lesions, bilaterality, diffuse pattern of lung involvement and older age group (≥ 50 years old) and increased duration of presenting complaint (≥ 4 days). There was significant association between crazy-paving pattern and increased duration of presenting complaint. No significant association could be detected between any CT pattern and increased patient age. Conclusion The most common CT feature of COVID-19 was multifocal ground glass opacity. Atypical features like cavitation and pleural effusion can occur early in the course of the disease. Our cases showed more extensive lesions with bilateral and diffuse patterns of distribution in the older age group and with increased duration of presenting complaint. There was a significant association between crazy-paving pattern and increased duration of presenting complaint. No significant association could be detected between any CT pattern and increased patient age.

scholarly journals Computed Tomography Features of COVID-19 in Children: A Systematic Review and Meta-analysis

2020 ◽  
Author(s):  
Ji-Gan Wang ◽  
Yu-Fang Mo ◽  
Yu-heng Su ◽  
Li-chuang Wang ◽  
Guang-bing Liu ◽  
...  
Keyword(s):  
Pleural Effusion ◽  
Assessment Tool ◽  
Meta Analysis ◽  
Ct Imaging ◽  
Chest Ct ◽  
Ground Glass ◽  
Imaging Features ◽  
Lung Lesions ◽  
Lung Lobe ◽  
Lung Ct

Objectives: To systematically analyze the chest CT imaging features of children with COVID-19 and provide references for clinical practice. Methods: We searched PubMed, Web of Science, and Embase; data published by Johns Hopkins University; and Chinese databases CNKI, Wanfang, and Chongqing Weipu. Reports on chest CT imaging features of children with COVID-19 from January 1, 2020, to August 10, 2020, were analyzed retrospectively and a meta-analysis carried out using Stata12.0 software. Results: Thirty-seven articles (1747 children) were included in this study. The overall rate of abnormal lung CT findings was 63.2% (95% confidence interval [CI]: 55.8-70.6%), with a rate of 61.0% (95% CI: 50.8-71.2%) in China and 67.8% (95% CI: 57.1-78.4%) in the rest of the world in the subgroup analysis. The incidence of ground-glass opacities was 39.5% (95% CI: 30.7-48.3%), multiple lung lobe lesions 65.1% (95% CI: 55.1-67.9%), and bilateral lung lesions 61.5% (95% CI: 58.8-72.2%). Other imaging features included nodules (25.7%), patchy shadows (36.8%), halo sign (24.8%), consolidation (24.1%), air bronchogram signs (11.2%), cord-like shadows (9.7%), crazy-paving pattern (6.1%), and pleural effusion (9.1%). Two articles reported three cases of white lung, another reported two cases of pneumothorax, and another one case of bullae. CONCLUSION: The lung CT results of children with COVID-19 are usually normal or slightly atypica, with a low sensitivity and specificity compared with that in adults. The lung lesions of COVID-19 pediatric patients mostly involve both lungs or multiple lobes, and the common manifestations are patchy shadows, ground-glass opacities, consolidation, partial air bronchogram signs, nodules, and halo signs; white lung, pleural effusion, and paving stone signs are rare. CLINICAL IMPACT: Therefore, chest CT has limited value as a screening tool for children with COVID-19 and can only be used as an auxiliary assessment tool.

scholarly journals Computed Tomography (CT) Imaging Features of Patients with COVID-19: Systematic Review and Meta-Analysis

2020 ◽  
Vol 2020 ◽  
pp. 1-8 ◽  
Author(s):  
Ephrem Awulachew ◽  
Kuma Diriba ◽  
Asrat Anja ◽  
Eyob Getu ◽  
Firehiwot Belayneh
Keyword(s):  
Ground Glass Opacity ◽  
Ct Imaging ◽  
Chest Ct ◽  
Ground Glass ◽  
Cochrane Library ◽  
Imaging Features ◽  
Severe Respiratory Distress ◽  
Ct Findings ◽  
Open Access Journals ◽  
Bilateral Lung

Introduction. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly contagious disease, and its first outbreak was reported in Wuhan, China. A coronavirus disease (COVID-19) causes severe respiratory distress (ARDS). Due to the primary involvement of the respiratory system, chest CT is strongly recommended in suspected COVID-19 cases, for both initial evaluation and follow-up. Objective. The aim of this review was to systematically analyze the existing literature on CT imaging features of patients with COVID-19 pneumonia. Methods. A systematic search was conducted on PubMed, Embase, Cochrane Library, Open Access Journals (OAJ), and Google Scholar databases until April 15, 2020. All articles with a report of CT findings in COVID-19 patients published in English from the onset of COVID-19 outbreak to April 20, 2020, were included in the study. Result. From a total of 5041 COVID-19-infected patients, about 98% (4940/5041) had abnormalities in chest CT, while about 2% have normal chest CT findings. Among COVID-19 patients with abnormal chest CT findings, 80% (3952/4940) had bilateral lung involvement. Ground-glass opacity (GGO) and mixed GGO with consolidation were observed in 2482 (65%) and 768 (18%) patients, respectively. Consolidations were detected in 1259 (22%) patients with COVID-19 pneumonia. CT images also showed interlobular septal thickening in about 691 (27%) patients. Conclusion. Frequent involvement of bilateral lung infections, ground-glass opacities, consolidation, crazy paving pattern, air bronchogram signs, and intralobular septal thickening were common CT imaging features of patients with COVID-19 pneumonia.

scholarly journals Clinical and CT features of mild-to-moderate COVID-19 cases after two sequential negative nucleic acid testing results: a retrospective analysis

2020 ◽  
Author(s):  
Yan Rong ◽  
Jing Wang ◽  
Jinfei Tian ◽  
Xinhua Liang ◽  
Yang Zhou ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Clinical Laboratory ◽  
Clinical Symptoms ◽  
Ground Glass Opacity ◽  
Ct Imaging ◽  
Ground Glass ◽  
Imaging Features ◽  
Nucleic Acid Testing ◽  
Imaging Data ◽  
Negative Results

Abstract Background Numerous studies have been focused on the clinical and imaging features among COVID-19 patients positive for SARS-CoV-2, but the data after negative is limited. We aims to describe these features after negative respiratory nucleic acid testing results.Methods From January 31 to February 28, 2020, 51 mild-to-moderate COVID-19 cases (median: 34.0 years and 47.1% male) were retrospectively enrolled. Demographic, clinical, laboratory, and CT imaging data were collected before and after two sequential negative results for respiratory SARS-CoV-2 .Results After negative for respiratory SARS-CoV-2, the clinical symptoms continued to recover and the abnormal imaging were observed for all of the moderate cases. 77.4% of the moderate patients had multi-lobar involvement and lesions were more frequent in the lower lobes. The most common CT imaging manifestations were ground glass opacity (51.6%) and fibrous stripes (54.8%%). Among 12 out of 31 moderate patients with repeated chest CT scan after negative for SARS-CoV-2, 7 patients (58.3%) with ground-glass absorption reduced over 60% within one week, but there were still 4 cases (13.8%) with absorption less than 5%.Conclusions The clinical symptoms and abnormal imaging persisted but continued to recover after negative for respiratory SARS-CoV-2.

scholarly journals CT Imaging Features During Disease Progression of 2019 Novel Coronavirus (COVID-19) Pneumonia

2020 ◽  
Vol 17 (4) ◽  
Author(s):  
Nan Yu ◽  
Yong Yu ◽  
Shubo Cai ◽  
Cong Shen ◽  
Youmin Guo
Keyword(s):  
Disease Progression ◽  
Symptom Onset ◽  
Early Stage ◽  
Ground Glass Opacity ◽  
Ct Imaging ◽  
Imaging Features ◽  
Imaging Characteristics ◽  
Novel Coronavirus ◽  
Stage 1

Objectives: To describe the characteristics of computed tomography (CT) in patients with 2019 novel coronavirus (COVID-19) pneumonia and their changes during disease progression. Patients and Methods: A total of 96 chest CT scans of 61 pneumonia patients associated with COVID-19 were reviewed to identify CT features associated with the time of symptom onset and the evolution of disease. Results: The initial CTs of 61 patients were obtained during 1 to 11 days after the onset. The main CT pattern of initial CT obtained during 1 - 3 days after the symptom onset was single (7/23, 35%) or multiple ground-glass opacity (GGO, 8/23, 35%). At 4 - 7 days after the symptom onset, the main imaging features were crazy paving GGO mixed with partial consolidation pattern (15/32, 47%). At 8 - 11 days after the symptom onset, the CT images showed consolidation pattern (3/6, 50%). A total of 35 follow up CTs were collected. The mean interval time between each follow up CT was 3 ± 2 days. The CT patterns also changed with the evolution of the disease: the features of GGO manifested at the early stage (1 - 3d). The crazy paving GGO pattern, consolidation pattern and mixed with partial consolidation pattern were found 4 to 14 days after the onset. In the absorption stage (15 - 24d), both density and extent of lesions were reduced. Conclusion: The CT imaging features are associated with the time of symptom onset and evolution of disease. Understanding the imaging characteristics of each stage is very helpful for understanding the development of disease.

Investigation of HRCT Chest Severity in Patients with COVID-19: A Study of Tertiary Care Hospital in Pakistan

2021 ◽  
Vol 15 (5) ◽  
pp. 1084-1089
Author(s):  
Saulat Sarfraz ◽  
Kh. Bilal Waheed ◽  
Masood Akhtar ◽  
Sarfraz Latif ◽  
Muhammad Asif ◽  
...  
Keyword(s):  
Tertiary Care ◽  
Lower Lobe ◽  
Ground Glass Opacity ◽  
Pulmonary Involvement ◽  
Clinical Severity ◽  
Ground Glass ◽  
Care Hospital ◽  
Imaging Features ◽  
High Resolution Computed Tomography ◽  
Cross Sectional

Background: High-resolution computed tomography (HRCT) chest has a key role in diagnosis COVID-19, as it provides specific imaging features, i.e., bilateral, peripheral and sub-pleural, ground-glass opacity (GGO), consolidation and many associated findings. Aim: To provide the detailed chest HRCT findings along with clinical information in patients with COVID-19. Methods: A cross-sectional study was conducted in the Department of Radiology SZPGMI, Lahore. Information on clinical data, chest radiography appearance and comorbidities were recorded ona designed proforma. HRCT chest findings were recorded in terms of pattern, distribution, laterality, and other findings. HRCT chest severity was calculated using a 25 point CT severity score. Kendall’s Tau test applied to investigate the correlation between the severity of HRCT chest with clinical severity levels of COVID-19. Results: Fever (74%) was the most reported presenting symptom, followed by dry cough (70%). The majority of patients had abnormal chest X-ray (57%) as well as abnormal HRCT chest (90%). The majority of patients were in mild clinical scoring levels of disease (61%) and mild category (49%) of HRCT chest severity. In majority of the patients (46%), all five pulmonary lobes were involved, whereas the right lower lobe was most frequently affected. The pattern of ground-glass opacity (GGO) was found in 82% of patients. Most common distribution was ‘peripheral’, reported in 90% patients. Multiple lobe involvement was found in 82% of patients. The unilateral pulmonary involvement was observed in 12% of patients, whereas, bilateral was found in 78% of patients. Reticulations were reported in 22% followed by atelectasis in 18% patients. Conclusion: COVID-19 patients usually present with abnormal HRCT chest, mostly with a benign course. Multiple pulmonary lobes are commonly involved, especially basal lobes with ground glass opacities. Clinical severity of the disease is reflected in HRCT findings. Keywords: COVID-19 Pandemic, HRCT Chest Findings, Ground Glass Opacity (GGO), Consolidation

Clinical characteristics and CT imaging features of COVID-19 on admission: A retrospective study

2021 ◽  
Vol 17 ◽  
Author(s):  
Changchun Liu ◽  
Jianping Cai ◽  
Mengmeng Zhang ◽  
Huizhen Li ◽  
Chunyan Liu ◽  
...  
Keyword(s):  
Ground Glass Opacity ◽  
Ct Imaging ◽  
Imaging Features ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Erythrocyte Sedimentation ◽  
Severe Group ◽  
Common Group ◽  
The Common ◽  
Interlobular Septal Thickening

Background and aims: Coronavirus disease 2019 (COVID-19) pandemic has become a global health issue. This study aimed to explore the clinical characteristics and CT imaging features of patients with COVID-19 on admission. Methods: Consecutive patients with laboratory-confirmed COVID-19 were retrospectively recruited to this study from January 2020 to March 2020. According to the disease severity status on admission, patients were divided into two groups, the common group and the severe group. Results: Forty-four patients (F/M 20/24) confirmed with COVID-19 were enrolled in this study. The most common onset symptom was fever (90.9%), followed by cough (43.2%). As for the laboratory tests, common findings included increased C reactive protein (47.7%) and erythrocyte sedimentation rate (43.2%), and decreased lymphocyte (34.1%). Frequency of decreased lymphocyte count and increased lactate dehydrogenase were higher in the severe group (n=14) than in the common group (n=30). About 86% patients showed typical imaging findings of COVID-19 infection including ground-glass opacity with ill-defined margins, air bronchogram, interlobular septal thickening, and consolidation. Lesions mainly located peripherally and subpleurally with diffuse distribution and multiple lung lobes affected. Conclusion: Fever and cough are the most common onset symptoms of COVID-19. Increased C reactive protein and erythrocyte sedimentation rate were the most common laboratory findings. Typical signs of chest CT imaging of COVID-19 included ground-glass opacity with ill-defined margins, air bronchogram, interlobular septal thickening, and consolidation.

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