Clinical investigation of the effect of calcium hydroxide intracanal dressing on bacterial lipopolysaccharide reduction from infected root canals

2013 ◽  
Vol 41 (1) ◽  
pp. 12-16 ◽  
Author(s):  
Alireza Adl ◽  
Mohammad Motamedifar ◽  
Mahdi Sedigh Shams ◽  
Ahmad Mirzaie
Keyword(s):  
Calcium Hydroxide ◽  
Clinical Investigation ◽  
Bacterial Lipopolysaccharide ◽  
Root Canals ◽  
Infected Root

scholarly journals Effectiveness of calcium hydroxide in reducing bacterial load comparing with chemo-mechanical preparation- A systematic review

2019 ◽  
Author(s):  
SaiSiva Naga GayathriNaidu ◽  
B Vikram Simha ◽  
Koka Krishna Mohan ◽  
Rammohan Modem ◽  
Kommineni Harish Chowdary
Keyword(s):  
Clinical Trials ◽  
Calcium Hydroxide ◽  
Bacterial Load ◽  
Bacterial Reduction ◽  
Bacterial Populations ◽  
Hand Search ◽  
Root Canals ◽  
Mechanical Preparation ◽  
Infected Root ◽  
Significant Difference

Aim: To determine and compare to what extent the intra-canal medicament like calcium hydroxide along with chemo-mechanical preparation reduces the bacterial load in infected root canals. Methodology: PubMed Cental, Medline, Google Scholar and hand search was carried out using the keywords calcium hydroxide (Ca(OH)2) , intra-canal medicament(ICM) and chemo-mechanical preparation. Selection Criteria: Clinical trials in which bacterial samples were evaluated at 3 intervals (Baseline, after chemo-mechanical preparation, after dressing with intra canal medicament ICM and trials which use Ca(OH)2 with any vehicle as ICM, but not compared with any other ICM were selected for this review. The data collection form was customized. The primary outcome measures were reduction of bacterial populations in infected root canals. Results: Seven clinical trials that met all inclusion criteria involving 117 participants were reviewed. Included studies showed significant difference in bacterial reduction after chemo-mechanical preparation and placement of Ca(OH)2 dressing for a week. In all included trials, Ca(OH)2 reduced bacterial load further compared with chemo-mechanical preparation. Conclusion: Ca(OH)2 as an inter-appointment medication promoted further decrease in the bacterial bioburden to levels significantly below those achieved by the chemo-mechanical procedures alone. Intra-canal medicament such as Ca(OH)2 should be considered for bacterial reduction along with chemo-mechanical preparation for long term success. Key Words: Intra-canal medicament, calcium hydroxide, Root canal treatment, bacterial load, Pulpitis

Clinical Investigation of the Efficacy of Chemomechanical Preparation with Rotary Nickel-Titanium Files for Removal of Endotoxin from Primarily Infected Root Canals

2010 ◽  
Vol 36 (11) ◽  
pp. 1766-1769 ◽  
Author(s):  
Frederico C. Martinho ◽  
Wanderson M.M. Chiesa ◽  
Ariane C.S. Marinho ◽  
Alexandre A. Zaia ◽  
Caio C.R. Ferraz ◽  
...  
Keyword(s):  
Clinical Investigation ◽  
Nickel Titanium ◽  
Root Canals ◽  
Infected Root

scholarly journals Periradicular repair after two-visit endodontic treatment using two different intracanal medications compared to single-visit endodontic treatment

2007 ◽  
Vol 18 (4) ◽  
pp. 299-304 ◽  
Author(s):  
Adriana M. Vieira Silveira ◽  
Hélio P. Lopes ◽  
José F. Siqueira Jr ◽  
Sérgio B. Macedo ◽  
Alberto Consolaro
Keyword(s):  
Success Rate ◽  
Calcium Hydroxide ◽  
Enterococcus Faecalis ◽  
Endodontic Treatment ◽  
Controversial Issues ◽  
Single Visit ◽  
Root Canals ◽  
Infected Root

The number of appointments necessary to treat infected root canals is one of the most controversial issues in endodontics. This study evaluated, in dogs, the response of the periradicular tissues to the endodontic treatment of infected root canals performed in a single visit or in two visits, using different interappointment dressings. Periradicular lesions were induced by inoculating Enterococcus faecalis in the root canals. After confirming that a periradicular lesion developed, the root canals were treated within one or two visits, using either ozonized oil or calcium hydroxide in camphorated paramonochlorophenol (CMCP) as an intracanal medication. After 6 months, the animals were sacrificed and the specimens were processed for histological and histobacteriological analysis. The root canals treated in a single visit showed a success rate of 46%. When a calcium hydroxide/CMCP-based interappointment intracanal medication was used, 74% of the cases were categorized as success. In cases where ozonized oil was used as the intracanal medication, a success rate of 77% was observed. These results of the present study demonstrated that the two-visit treatment offered a higher success rate compared to one-visit therapy. In addition, ozonized oil may potentially be used as an intracanal medication.

Antimicrobial Activity of Calcium Hydroxide Synthesized from Indonesian Limestone against Enterococcus faecalis

2021 ◽  
Vol 1044 ◽  
pp. 171-177
Author(s):  
Myrna Nurlatifah Zakaria ◽  
Ida Rodiyah Siti Halimah ◽  
Atia Nurul Sidiqa ◽  
Ira Artilia ◽  
Arief Cahyanto
Keyword(s):  
Calcium Hydroxide ◽  
Enterococcus Faecalis ◽  
Root Canal ◽  
Antimicrobial Property ◽  
Antimicrobial Effect ◽  
Antimicrobial Activities ◽  
Negative Control ◽  
Root Canals ◽  
Infected Root

Recurrent endodontic infections of treated teeth are mainly linked to microbial persistency in the root canal system. Enterococcus faecalis is a bacterium that is often identified in these recurrent infections. Calcium hydroxide (Ca(OH)2) is a widely used root canal medicament and is now being developed to be produced from natural materials. Ca(OH)2, which is synthesized from natural limestone from Palimanan, Indonesia, has a structure similar to Ca(OH)2, which is often used as a root canal medicament. The purpose of this study was to determine the antimicrobial property of Ca(OH)2 paste synthesized from natural limestone compared to conventional Ca(OH)2 paste. This study is an in vitro experimental study consists of 3 groups (n=24, namely, conventional Ca(OH)2 paste, limestone synthesized Ca(OH)2 paste, and saline as the negative control, for 2 intervals of time and evaluated by Total Plate Counting (TPC) method. Samples were mandibular first premolar root canal prepared by root canal preparation and contaminated with E. faecalis (ATCC 29212). The infected root canals of each group were treated by the medicaments, and samples from the root canals were taken on day 7 (n=4) and 14 (n=4). Results showed that both Ca(OH)2 groups had antimicrobial activities against E. faecalis. The limestone Ca(OH)2 paste group had the least amount of bacterial colonies on the 7th day compared to other groups. In contrast, on the 14th day, the conventional Ca(OH)2 paste had the least bacterial colonies. It can be concluded that the Ca(OH)2 paste synthesized from natural limestone has an antimicrobial effect on E. faecalis, the antimicrobial effect was higher on the 7th day but decreases on the 14th day, whereas the conventional Ca(OH)2 had a higher antimicrobial effect on day 14 compared to day 7. Further studies are expected to improve the long-term antimicrobial effectiveness and sustainability of the natural limestone synthesized Ca(OH)2 paste.

scholarly journals Antibacterial effectiveness in vitro of different formulations of calcium hydroxide paste

2017 ◽  
Vol 65 (4) ◽  
pp. 293-298
Author(s):  
Israel Alexandre De Araujo SENA ◽  
Isaac Jordão De Souza ARAÚJO ◽  
Marquiony Marques Dos SANTOS ◽  
Isabela Pinheiro Cavalcanti LIMA
Keyword(s):  
Antibacterial Activity ◽  
Calcium Hydroxide ◽  
Enterococcus Faecalis ◽  
Significant Inhibition ◽  
Diffusion Method ◽  
Significance Level ◽  
Root Canals ◽  
Infected Root ◽  
Inhibition Zones

ABSTRACT Objective: To evaluate the antibacterial activity of four formulations of calcium hydroxide paste against microorganisms commonly found in infected root canals. Methods: To evaluate antibacterial activity through the agar diffusion method, pastes of calcium hydroxide were made from its pro-analysis form, diffused into four separate vehicles: distilled water, camphorated p-monochlorophenol, propylene glycol and Otosporin®, testing the antimicrobial activity of these on strains of Staphylococcus aureus, Bacillus subtilis and Enterococcus faecalis. After the incubation period, the presence or otherwise of inhibition zones were observed and their sizes in three stages: 24h, 48h and 72h. With this data, the median between the four dishes was obtained and the consequent value was submitted to Kruskal-Wallis nonparametric statistical analysis, with post-tests of Mann-Whitney and Bonferroni correction, at a significance level of 5%. Results: Only pastes with camphorated p-monochlorophenol and Otosporin vehicles caused the formation of significant inhibition zones, with medians of 8.0 mm. Against the strains of Enterococcus faecalis, only pastes with the camphorated p-monochlorophenol vehicle resulted in the formation of significant inhibition zones, with a median of 3.0 mm. Conclusion : Otosporin and CMCP vehicles provide greater antimicrobial potential to calcium hydroxide against the studied bacteria. However, only the Ca(OH)2 and CMCP combination was effective against all the strains, and can thus be regarded as the paste formulation with the greatest antimicrobial effectiveness in this study.

Does Calcium Hydroxide Reduce Endotoxins in Infected Root Canals? Systematic Review and Meta-analysis

2020 ◽  
Vol 46 (11) ◽  
pp. 1545-1558 ◽  
Author(s):  
Natália Rocha Bedran ◽  
Patricia Nadelman ◽  
Marcela Baraúna Magno ◽  
Aline de Almeida Neves ◽  
Daniele Masterson Ferreira ◽  
...  
Keyword(s):  
Systematic Review ◽  
Calcium Hydroxide ◽  
Meta Analysis ◽  
Root Canals ◽  
Infected Root
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